KAT2A complexes ATAC and SAGA play unique roles in cell maintenance and identity in hematopoiesis and leukemia

Autor: Antonio Curti, Liliana Arede, Elena Foerner, R Samarista, M Mollenhauer-Starkl, Ana Filipa Domingues, Laszlo Tora, Rashmi Kulkarni, Brian J. P. Huntly, E Scheer, H Davison, Shikha Gupta, S Kleinwaechter, Ryan Asby, S Wind, A Chandru, D Forte, George Giotopoulos, Cristina Pina

Publikováno v: Blood Advances
Blood Advances, The American Society of Hematology, 2022, 6 (1), pp.165-180. ⟨10.1182/bloodadvances.2020002842⟩
Blood Advances, 2021, 6 (1), pp.165-180. ⟨10.1182/bloodadvances.2020002842⟩
Blood Advances, The American Society of Hematology, 2021, ⟨10.1182/bloodadvances.2020002842⟩

Key Points KAT2A is required at different stages of human cord blood erythroid development with ATAC and SAGA complex specificity.KAT2A regulates leukemia cell maintenance and identity through specific participation in ATAC and SAGA complexes.
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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5befb0762a8f2ea745f9e5fd594bbba1
https://hal.archives-ouvertes.fr/hal-03552114

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