Zobrazeno 1 - 3
of 3
pro vyhledávání: '"R S Rivest"'
Publikováno v:
Biochemical Pharmacology. 31:2505-2511
The inhibition of protein synthesis by 8-azaguanine (azaG) in L1210 cells in culture was investigated. AzaG selectively inhibited protein synthesis at concentrations where viability was decreased significantly. AzaG altered the polyribosome sedimenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e5b6b706fd1c6d26f50b0f68bb13841
https://doi.org/10.1016/0006-2952(82)90061-2
https://doi.org/10.1016/0006-2952(82)90061-2
Autor:
C S Portlock, M. D. Carman, R S Rivest, T Duffy, S Srimatkandada, Jan H. Schornagel, Joseph R. Bertino
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2(1)
A patient is described with acute myelocytic leukemia refractory to conventional therapy, who also became highly resistant to methotrexate (MTX) after repeated courses of this drug. Leukemia cells from this patient were found to contain an elevated l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84782f8ca6db9b1428d9126f01877fff
https://pubmed.ncbi.nlm.nih.gov/6583326
https://pubmed.ncbi.nlm.nih.gov/6583326
Publikováno v:
Cancer research. 42(10)
In L1210 cells in culture, 3-deazaguanine (DG), a relatively new purine analog, was found to inhibit DNA and protein synthesis but not total RNA synthesis. The effect of the drug on protein synthesis was therefore further examined. Polyadenylic acid-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4da823086ee01e4812d42c64b9826bed
https://pubmed.ncbi.nlm.nih.gov/7105000
https://pubmed.ncbi.nlm.nih.gov/7105000