Zobrazeno 1 - 10
of 34
pro vyhledávání: '"R S Mittler"'
Autor:
H. R. Cho, B. Kwon, H. Yagita, S. La, E. A. Lee, J.-E. Kim, H. Akiba, J. Kim, J.-H. Suh, D. S. Vinay, S.-A. Ju, B.-S. Kim, R. S. Mittler, K. Okumura, B. S. Kwon
Publikováno v:
Transplant International. 17:351-361
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e259b3532fc9635e092b7eb103bfe172
https://doi.org/10.1111/j.1432-2277.2004.tb00454.x
https://doi.org/10.1111/j.1432-2277.2004.tb00454.x
Publikováno v:
The Journal of Immunology. 153:84-96
Transfection of a CD4- Jurkat leukemic T cell line with the human wild-type CD4 gene resulted in the constitutive mobilization of calcium by these cells. The altered calcium phenotype was dependent on expression of a completely functional CD4 molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78c287df2e9e658df603d7daf4abbe80
https://doi.org/10.4049/jimmunol.153.1.84
https://doi.org/10.4049/jimmunol.153.1.84
Publikováno v:
The Journal of Immunology. 150:605-616
The binding and subsequent cross-linking of murine IgG2a or human IgG to the Fc gamma R on the monocytic cell line THP-1 induced a rapid, dose-dependent increase in tyrosine phosphorylation of several proteins (a doublet centered around 110 kDa, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a1162c63ee8c9b1de144357f49d759e
https://doi.org/10.4049/jimmunol.150.2.605
https://doi.org/10.4049/jimmunol.150.2.605
Publikováno v:
The Journal of Immunology. 148:2159-2162
By fluorescence resonance energy transfer, we have previously demonstrated that upon anti-CD3 mAb-mediated activation of a murine T cell hybridoma expressing human CD4, CD4 moves into close association with the TCR/CD3 complex. It was shown that this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2305800786b3c0e6ea8915965bdc4c7
https://doi.org/10.4049/jimmunol.148.7.2159
https://doi.org/10.4049/jimmunol.148.7.2159
Publikováno v:
The Journal of Immunology. 147:3434-3440
Activation of human PBL T cells with solid phase anti-CD3 mAb or during the course of an MLR response gives rise to the association of CD4 or CD8 molecules with the protein tyrosine phosphatase, CD45, on the cell surface. This paired association of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd6f789b1fa3f7e7b8f2b5044b14b9fb
https://doi.org/10.4049/jimmunol.147.10.3434
https://doi.org/10.4049/jimmunol.147.10.3434
Publikováno v:
The Journal of Immunology. 145:794-803
We describe the requirements for T cell activation by a mAb termed 4-10 that recognizes a novel determinant on MHC class I molecules. The determinant recognized by mAb 4-10 appears on resting T cells of all individuals tested (n greater than 30). Unl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::307a42426e7e38855ede4ebac08643bc
https://doi.org/10.4049/jimmunol.145.3.794
https://doi.org/10.4049/jimmunol.145.3.794
Publikováno v:
The Journal of Immunology. 144:1361-1368
Aggregation (e.g., through cross-linkage) of cell surface molecules is in various biologic systems a necessary event in cellular activation. Examining the Ia molecule on B cells we found that aggregation is a function of the surface Ag mobility; the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b1c67524612ebe8e1728f8e88de74de
https://doi.org/10.4049/jimmunol.144.4.1361
https://doi.org/10.4049/jimmunol.144.4.1361
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 37(9)
BACKGROUND Allergic asthma is a T-helper type 2 (Th2) cell-mediated chronic disease that is characterized by airway hyperreactivity (AHR) and chronic eosinophilic airway inflammation. Several studies suggest co-stimulatory molecules like CD137 as pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194408addbb00e8e6fa31c22a329f94c
https://pubmed.ncbi.nlm.nih.gov/17845419
https://pubmed.ncbi.nlm.nih.gov/17845419
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(9)
After recognition of Ag/MHC and ligation of a costimulatory molecule, resting T cells will clonally expand and then delete to very low levels. Previously, it was shown that deletion can be prevented by coinjection of cytokines or proinflammatory agen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c696ff2bc95e79265e5bb522859d858
https://pubmed.ncbi.nlm.nih.gov/10227968
https://pubmed.ncbi.nlm.nih.gov/10227968
Autor:
J A, Ledbetter, J A, Francisco, C B, Siegall, L K, Gilliland, D, Hollenbaugh, A, Aruffo, A W, Siadak, N, Mischel-Petty, L S, Grosmaire, M L, Gordon, T J, Brown, P, Moran-Davis, R S, Mittler, P A, Kiener, S G, Nadler
Publikováno v:
Critical reviews in immunology. 17(5-6)
A single-chain Fv (sFv) was expressed from the variable regions of the CD40-specific mAb G28-5. The molecule bound CD40 with a high affinity (2.2 nM) and was a monomer in solution. Surprisingly, G28-5 sFv was a potent CD40 agonist that rapidly crossl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::171a70b06a698b40ba223ec40c0805fd
https://pubmed.ncbi.nlm.nih.gov/9419430
https://pubmed.ncbi.nlm.nih.gov/9419430