Zobrazeno 1 - 10
of 194
pro vyhledávání: '"R S K Chaganti"'
Autor:
James E Korkola, Sandy Heck, Adam B Olshen, Darren R Feldman, Victor E Reuter, Jane Houldsworth, George J Bosl, R S K Chaganti
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0142846 (2015)
Germ Cell Tumors (GCT) have a high cure rate, but we currently lack the ability to accurately identify the small subset of patients who will die from their disease. We used a combined genomic and expression profiling approach to identify genomic regi
Externí odkaz:
https://doaj.org/article/12cc09e6abed473e89953e6de7cf0eae
Autor:
Nirmala Jagadish, R. S. K. Chaganti, Rekha Soni, Manjunath Kustagi, James E. Korkola, Ritu Kushwaha, George J. Bosl, Geetu Mendiratta, Andrea Califano, Marco Seandel, Venkata Thodima
Publikováno v:
Stem Cell Reports, Vol 6, Iss 5, Pp 772-783 (2016)
Stem Cell Reports
Stem Cell Reports
Summary Human male germ cell tumors (GCTs) are derived from primordial germ cells (PGCs). The master pluripotency regulator and neuroectodermal lineage effector transcription factor SOX2 is repressed in PGCs and the seminoma (SEM) subset of GCTs. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d231770fcba92155122d38071a45d900
http://www.sciencedirect.com/science/article/pii/S221367111630008X
http://www.sciencedirect.com/science/article/pii/S221367111630008X
Autor:
R. S. K. Chaganti, Charles Ma, Venkata Thodima, Lizalynn M. Dias, Asha Guttapalli, Sergei Syrbu, Imran Siddiqi, Geetu Mendiratta, Julia Friedman, Jane Houldsworth
Publikováno v:
Leukemia & Lymphoma. 57:899-908
Genomic copy number alterations (CNAs) in diffuse large B-cell lymphoma (DLBCL) have roles in disease pathogenesis, but overall clinical relevance remains unclear. Herein, an unbiased algorithm was uniformly applied across three genome profiling data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05a52667042eaedcd2b21e2bc76d025
https://doi.org/10.3109/10428194.2015.1080364
https://doi.org/10.3109/10428194.2015.1080364
Autor:
Steven C. Campbell, Eric A. Klein, Jane Houldsworth, Subhadra V. Nandula, R. S. K. Chaganti, Cristina Magi-Galluzzi, Christopher G. Przybycin, Brian I. Rini, Banumathy Gowrishankar, Charles Ma
Publikováno v:
Journal of Urology. 193:1479-1485
Accurate discrimination of benign oncocytoma and malignant renal cell carcinoma is useful for planning appropriate treatment strategies for patients with renal masses. Classification of renal neoplasms solely based on histopathology can be challengin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1f0a78de3250ca0dd30aa690b399823
https://doi.org/10.1016/j.juro.2014.11.099
https://doi.org/10.1016/j.juro.2014.11.099
Publikováno v:
Stem Cells and Development. 23:1149-1156
MicroRNAs (miRNAs) regulate myriad biological processes; however, their role in cell fate choice is relatively unexplored. Pluripotent NT2/D1 embryonal carcinoma cells differentiate into an epithelial/smooth muscle phenotype when treated with bone mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b02130cdb1188d5c033d8d59d7b3d1
https://doi.org/10.1089/scd.2013.0262
https://doi.org/10.1089/scd.2013.0262
Autor:
Asha Guttapalli, Gouri Nanjangud, R. S. K. Chaganti, Nicholas Chiorazzi, Xiao-Jie Yan, Jane Houldsworth, Sujata Patil, Jennifer R. Brown, Tania Zielonka, Kanti R. Rai, Weiyi Chen, Venkata Thodima, Anthony R. Mato, Geetu Mendiratta
Publikováno v:
Leukemia & Lymphoma. 55:920-928
Array comparative genomic hybridization (aCGH) has yet to be fully leveraged in a prognostic setting in chronic lymphocytic leukemia (CLL). Genomic imbalance was assessed in 288 CLL specimens using a targeted array. Based on 20 aberrations in a hiera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed46ae61d253427f30354a44f87fa7f3
https://doi.org/10.3109/10428194.2013.845882
https://doi.org/10.3109/10428194.2013.845882
Autor:
R. S. K. Chaganti, Venkata Thodima, Shai Posner, Ana M. Molina, Robert J. Motzer, Miguel A. López-Lago
Publikováno v:
Oncogene
The mechanism by which renal cell carcinoma (RCC) colonizes the lung microenvironment during metastasis remains largely unknown. To investigate this process, we grafted human RCC cells with varying lung metastatic potential in mice. Gene expression p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef592b36e83bdbbbb58ae504c68e518
https://doi.org/10.1038/onc.2012.201
https://doi.org/10.1038/onc.2012.201
Publikováno v:
Leukemia & Lymphoma. 49:2170-2180
The principal curative agent in the front-line treatment of patients with diffuse large B-cell lymphoma (DLBCL) is the anthracycline, doxorubicin. To define pathways that may have a functional role in the response of DLBCL in vivo to doxorubicin-base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9ca6c1676775c74d4b4e2fb6afce240
https://doi.org/10.1080/10428190802428369
https://doi.org/10.1080/10428190802428369
Autor:
R. S. K. Chaganti, James E. Korkola, Victor E. Reuter, G. Varuni Kondagunta, Robert J. Motzer
Publikováno v:
Journal of Urology. 177:1264-1268
Purpose: We identified differentially expressed genes associated with response to pegylated interferon-α treatment in patients with renal cell carcinoma.Materials and Methods: We performed expression profiling on renal cell carcinoma specimens isola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80d835caef2113dfd0f2a9c4d7d3130d
https://doi.org/10.1016/j.juro.2006.11.087
https://doi.org/10.1016/j.juro.2006.11.087
Autor:
R. S. K. Chaganti, Pulivarthi H. Rao, Gouri Nanjangud, S. Mehra, Andrew D. Zelenetz, J. Qin, Gerard B. Donnelly, Suresh C. Jhanwar, Julie Teruya-Feldstein
Publikováno v:
Cytogenetic and Genome Research. 118:337-344
We analyzed a cohort of 61 follicular lymphomas (FL) with an abnormal G-banded karyotype by spectral karyotyping (SKY) to better define the chromosome instability associated with the t(14;18)(q32;q21) positive and negative subsets of FL and histologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e23d0ddc4de65b6300d6b609f8cea7a
https://doi.org/10.1159/000108318
https://doi.org/10.1159/000108318