Zobrazeno 1 - 10
of 21
pro vyhledávání: '"R S Jope"'
Publikováno v:
Translational Psychiatry
Suicide is one of the leading causes of death in the United States, yet it remains difficult to understand the mechanistic provocations and to intervene therapeutically. Stress is recognized as a frequent precursor to suicide. Psychological stress is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cdaa291033aabc6eeca71df0276d77e
https://pubmed.ncbi.nlm.nih.gov/25514751
https://pubmed.ncbi.nlm.nih.gov/25514751
Stimulation of death receptors activates the extrinsic apoptotic signaling pathway that leads to cell death. Although many steps of this apoptotic signaling cascade are known, few mechanisms that counterbalance the death signal have been described. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96cf46c7fe4825a43cd064b660621533
https://europepmc.org/articles/PMC2662711/
https://europepmc.org/articles/PMC2662711/
Publikováno v:
Neurochemical research. 26(7)
Muscarinic receptor-mediated changes in protein tyrosine phosphorylation were examined in differentiated human neuroblastoma SH-SY5Y cells. Treatment of differentiated cells with 1 mM carbachol caused rapid increases in the tyrosine phosphorylation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::981ad760094b123350e0cbb29a47bd54
https://pubmed.ncbi.nlm.nih.gov/11565612
https://pubmed.ncbi.nlm.nih.gov/11565612
Publikováno v:
The Journal of biological chemistry. 275(11)
The potential role of glycogen synthase kinase-3beta in modulating apoptosis was examined in human SH-SY5Y neuroblastoma cells. Staurosporine treatment caused time- and concentration-dependent increases in the activities of caspase-3 and caspase-9 bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b17adb82fd0cd74ae182b430e8f2e1b
https://pubmed.ncbi.nlm.nih.gov/10713065
https://pubmed.ncbi.nlm.nih.gov/10713065
Publikováno v:
Journal of neuroscience research. 55(3)
This study's goals were to more fully define the activation of protein tyrosine phosphorylation stimulated by muscarinic receptors, to test if this signaling process is affected by oxidative stress induced by H2O2, and to compare the effects of H2O2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::97b5abe352d710542bbf2c5822bb378b
https://pubmed.ncbi.nlm.nih.gov/10348664
https://pubmed.ncbi.nlm.nih.gov/10348664
Publikováno v:
The Journal of biological chemistry. 269(27)
We examined the regulation of an amiloride-sensitive sodium conductance expressed in human B lymphoid cells. This conductance was activated by two independent pathways, one involving cyclic adenylyl monophosphate (cAMP)-dependent protein kinase and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d482da4488d5e9a3a16834bb46275202
https://pubmed.ncbi.nlm.nih.gov/8027031
https://pubmed.ncbi.nlm.nih.gov/8027031
Autor:
R S, Jope
Publikováno v:
Progress in brain research. 98
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::039f300cc0e15611859f3a9781ceb99b
https://pubmed.ncbi.nlm.nih.gov/8248521
https://pubmed.ncbi.nlm.nih.gov/8248521
Publikováno v:
Neurotoxicology. 13(2)
Administration of 0.3% aluminum in drinking water elevated serum aluminum concentrations 8-fold in rats. Further, chronic treatment with aluminum for 2-3 mon, in both developing and adult rats, significantly decreased the levels of MAP-2 in brain, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b683b56ed152b4ef70dbdf13d12bf1f8
https://pubmed.ncbi.nlm.nih.gov/1331920
https://pubmed.ncbi.nlm.nih.gov/1331920
Publikováno v:
Neurotoxicology. 13(2)
The influence of seizures on phosphoinositide hydrolysis and protein kinase C activity was measured in rat hippocampus and cerebral cortex, primarily using a model in which generalized convulsive status epilepticus was induced by administration of Li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c35e472b3946a15caac27e7c59c43c9
https://pubmed.ncbi.nlm.nih.gov/1331919
https://pubmed.ncbi.nlm.nih.gov/1331919
Autor:
R S, Jope, G V, Johnson
Publikováno v:
Ciba Foundation symposium. 169
Neurochemical responses to chronic oral aluminium administration have been studied in rats. Aluminium (0.3%) was added to drinking water of adult rats for four weeks or longer and weanling rats were given aluminium for eight weeks. Selective cognitiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1ed82f051d61a89af601daaacca8040d
https://pubmed.ncbi.nlm.nih.gov/1337035
https://pubmed.ncbi.nlm.nih.gov/1337035