Zobrazeno 1 - 6
of 6
pro vyhledávání: '"R S Boger"'
Publikováno v:
Transplantation. 71(10)
The effects of three doses of RAD (40-O-[2-hydroxyethyl]-rapamycin), a novel macrolide with potent immunosuppressive and antiproliferative properties, on the incidence and severity of acute rejection episodes as well as its tolerability were evaluate
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 20(6)
This study describes the relationship between the measured effects (angiotensin I and renal plasma flow) and plasma drug levels using a combined pharmacokinetic-pharmacodynamic model after 90 min iv infusion of enalkiren in 15 healthy, salt-depleted
Autor:
D Moyse, A Cohen, J H Cavanaugh, H D Kleinert, R R Luther, J Lamm, R S Boger, H N Glassman, P J Schmitz
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 15(6 Pt 2)
The effects of sustained renin inhibition by repeated administration of enalkiren (A-64662), the novel dipeptide renin inhibitor, were evaluated in a randomized, double-blind, placebo-controlled, parallel-group study of 32 inpatients (eight per group
Publikováno v:
Circulation. 81(6)
To evaluate the participation of the renin-angiotensin system in sustaining hypertension, we administered the specific dipeptide renin inhibitor enalkiren (A-64662) to 18 patients with essential hypertension. Ascending intravenous bolus doses (0.03,
Autor:
Jo l M nard, R. S. Boger, Than T. Guyenne, H D Kleinert, R. P. Manski, H. N. Glassman, R. R. Luther
Publikováno v:
Journal of Hypertension. 11:S457
Autor:
R R Luther, Jürg Nussberger, Bernard Waeber, H D Kleinert, H. R. Brunner, R S Boger, M Porchet, A. Delabays, P Hoyos, H N Glassman
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 13(6 Pt 2)
The effect of the renin inhibitor enalkiren (Abbott-64662) was evaluated in eight normal volunteer subjects on a standardized sodium diet (100 mmol/day) by measurement of various components of the renin-angiotensin system and drug levels in plasma. O