Zobrazeno 1 - 10
of 25
pro vyhledávání: '"R S Boger"'
Publikováno v:
Transplantation. 71(10)
The effects of three doses of RAD (40-O-[2-hydroxyethyl]-rapamycin), a novel macrolide with potent immunosuppressive and antiproliferative properties, on the incidence and severity of acute rejection episodes as well as its tolerability were evaluate
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 20(6)
This study describes the relationship between the measured effects (angiotensin I and renal plasma flow) and plasma drug levels using a combined pharmacokinetic-pharmacodynamic model after 90 min iv infusion of enalkiren in 15 healthy, salt-depleted
Publikováno v:
Clinical nephrology. 36(4)
The renin-angiotensin system (RAS) is an important modulator of blood pressure and fluid balance. The clinical success of angiotensin converting enzyme inhibitors (ACEIs) in the treatment of hypertension has stimulated the search for antagonists of r
Autor:
D Moyse, A Cohen, J H Cavanaugh, H D Kleinert, R R Luther, J Lamm, R S Boger, H N Glassman, P J Schmitz
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 15(6 Pt 2)
The effects of sustained renin inhibition by repeated administration of enalkiren (A-64662), the novel dipeptide renin inhibitor, were evaluated in a randomized, double-blind, placebo-controlled, parallel-group study of 32 inpatients (eight per group
Publikováno v:
Circulation. 81(6)
To evaluate the participation of the renin-angiotensin system in sustaining hypertension, we administered the specific dipeptide renin inhibitor enalkiren (A-64662) to 18 patients with essential hypertension. Ascending intravenous bolus doses (0.03,
Autor:
Jo l M nard, R. S. Boger, Than T. Guyenne, H D Kleinert, R. P. Manski, H. N. Glassman, R. R. Luther
Publikováno v:
Journal of Hypertension. 11:S457
Autor:
R R Luther, Jürg Nussberger, Bernard Waeber, H D Kleinert, H. R. Brunner, R S Boger, M Porchet, A. Delabays, P Hoyos, H N Glassman
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 13(6 Pt 2)
The effect of the renin inhibitor enalkiren (Abbott-64662) was evaluated in eight normal volunteer subjects on a standardized sodium diet (100 mmol/day) by measurement of various components of the renin-angiotensin system and drug levels in plasma. O
Autor:
Tashie, Worlanyo1 (AUTHOR), Fondjo, Linda Ahenkorah1 (AUTHOR), Owiredu, William K. B. A.1 (AUTHOR), Ephraim, Richard K. D.2 (AUTHOR), Asare, Listowell3 (AUTHOR), Adu-Gyamfi, Enoch Appiah4 (AUTHOR), Seidu, Laila3 (AUTHOR)
Publikováno v:
BioMed Research International. 10/22/2020, p1-9. 9p.
Autor:
Singh, Ashish Kumar1 (AUTHOR), Sharma, Rajni1,2 (AUTHOR), Singh, Minni3 (AUTHOR), Verma, Neelam1,4 (AUTHOR) verma.neelam2@gmail.com
Publikováno v:
Instrumentation Science & Technology. 2020, Vol. 48 Issue 4, p400-416. 17p.
Publikováno v:
VCOT: Veterinary & Comparative Orthopaedics & Traumatology; 2021, Vol. 34 Issue 4, p279-286, 8p