Zobrazeno 1 - 10
of 19
pro vyhledávání: '"R S Birnbaum"'
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 81:3774-3782
Insulin-like growth factors (IGFs) and the type 1 IGF receptor (IGF-R) are involved in normal growth and development of the human prostate. Changes in levels of IGF-R and IGFs have been shown for several malignancies. Immunohistochemistry and in situ
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 81:618-624
Insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) is produced by prostate epithelial and stromal cells and either enhances or inhibits the effects of IGF on prostate epithelial cells. The levels of this protein in the male reproductive tra
Publikováno v:
Journal of cellular physiology. 175(1)
Recent studies have indicated that the insulin-like growth factors (IGFs) stimulate skeletal myoblast proliferation and differentiation. However, the question of whether IGFs are required for myoblast differentiation has not been resolved. To address
Publikováno v:
The Journal of clinical endocrinology and metabolism. 81(10)
Insulin-like growth factor (IGF)-binding proteins (IGFBPs) modulate the actions of IGF. We have previously reported that IGFBP-2 messenger ribonucleic acid (mRNA) and protein are increased, and IGFBP-3 protein decreased in malignant prostate epitheli
Publikováno v:
The Journal of clinical endocrinology and metabolism. 81(1)
Insulin-like growth factor (IGF)-binding proteins (IGFBPs) modulate the activity of IGFs. In vitro human prostate epithelial cells secrete IGFBP-2 and -3. In vivo IGFBP-2 is increased, and IGFBP-3 is decreased in the serum of patients with prostate c
Publikováno v:
Endocrinology. 136(3)
The network of androgen-dependent growth factors regulating the growth and function of normal or neoplastic prostate epithelium is largely unknown. To facilitate studies directed at investigating this issue, androgen receptor-negative (AR-) PC3 prost
Autor:
D L, Andress, R S, Birnbaum
Publikováno v:
The Journal of biological chemistry. 267(31)
Insulin-like growth factor (IGF)-binding proteins (IGFBPs) either inhibit or enhance IGF-stimulated cellular effects. While inhibition occurs by sequestration of IGF from cell-surface receptors, the exact mechanism of IGF-enhancement remains undefine
Publikováno v:
Journal of Biological Chemistry. 257:241-244
The terminal hexadecapeptide sequence of preprocalcitonin (termed carboxyl-adjacent peptide, CAP, for its position relative to calcitonin) has been synthesized to establish a radioimmunoassay for an investigation of cross-reacting peptides in extract
Publikováno v:
Journal of Biological Chemistry. 255:2645-2648
Messenger RNA from calcitonin-secreting rat medullary thyroid carcinoma lines directs the synthesis of a putative precursor of calcitonin when translated in wheat embryo lysate. The major translation product directed by mRNA isolated from a rat tumor
Autor:
P J, Gkonos, W, Born, B N, Jones, J B, Petermann, H T, Keutmann, R S, Birnbaum, J A, Fischer, B A, Roos
Publikováno v:
The Journal of biological chemistry. 261(31)
cDNA analyses predict that the human calcitonin gene encodes the two precursor proteins of calcitonin and calcitonin gene-related peptide (CGRP). The mRNAs for the putative precursors of these peptides are derived from alternative processing of the p