Zobrazeno 1 - 9
of 9
pro vyhledávání: '"R S, Whitaker"'
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(3)
The molecular biology underlying the metastatic process in ovarian carcinoma remains poorly understood. For other neoplasms, the induction of angiogenesis by malignant cells has been shown to play a pivotal role in the process of tumor proliferation
Publikováno v:
Cancer research. 58(23)
Ovarian cancer is a highly lethal disease with metastases present in the majority of patients at the time of diagnosis. The molecular mechanisms underlying the metastatic process of this cancer are not well understood. One family of cell-associated a
Autor:
G C, Rodriguez, D K, Walmer, M, Cline, H, Krigman, B A, Lessey, R S, Whitaker, R, Dodge, C L, Hughes
Publikováno v:
Journal of the Society for Gynecologic Investigation. 5(5)
The apoptosis pathway is a vital mechanism in vivo that functions to eradicate genetically damaged cells prone to malignancy. The purpose of this study was to determine whether oral contraceptives, which confer significant protection against subseque
Autor:
L J, Havrilesky, J A, Hurteau, R S, Whitaker, A, Elbendary, S, Wu, G C, Rodriguez, R C, Bast, A, Berchuck
Publikováno v:
Cancer research. 55(4)
Previously, we found that transforming growth factor beta (TGF-beta) inhibits proliferation of normal human ovarian epithelial cells. In addition, although only 1 of 5 immortalized ovarian cancer cell lines was inhibited, TGF-beta inhibited prolifera
Publikováno v:
Cancer. 74(1)
Previously, the authors found that immortalized ovarian cancer cell lines generally were resistant to the growth inhibitory effect of transforming growth factor-beta and frequently had lost the ability to produce or activate this growth factor. In th
Autor:
S J, McKenzie, K A, DeSombre, B S, Bast, D R, Hollis, R S, Whitaker, A, Berchuck, C M, Boyer, R C, Bast
Publikováno v:
Cancer. 71(12)
The HER-2 neu (c-erbB-2) oncogene product p185neu is expressed by most ovarian cancers and overexpressed in approximately 30%.Sera from patients with ovarian cancer were evaluated for neu antigen using an enzyme-linked immunoassay and for CA 125 anti
Publikováno v:
American journal of obstetrics and gynecology. 164(3)
Previously we have shown that epidermal growth factor acts as a mitogen for some, but not all, ovarian cancer cells in culture. In this study we examined the effect of epidermal growth factor on proliferation of normal human ovarian epithelial cells
Publikováno v:
Journal of the Fisheries Research Board of Canada. 26:1694-1696
Ligation of an adult Atlantic salmon with a cord created a bruise in the epaxial muscles similar to that observed in a salmon caught by a nylon gillnet. There were no external manifestations of these lesions. Although only 10 such salmon have been ob
Publikováno v:
Nature. 205:621-622
THE dechlorination of 2,2-bis-(p-chlorophenyl)-1,1,1-trichloroethane (DDT) to 2,2-bis-(p-chlorophenyl)-1,1-di-chloroethane (DDD) by various animals has been reported recently1,2. The same detoxification reaction appears to be carried out by yeasts3.