Zobrazeno 1 - 10
of 16
pro vyhledávání: '"R S, Thies"'
Autor:
Hans Reinecke, Akiko Futakuchi-Tsuchida, Charles E. Murry, Xiulan Yang, Bjorn C. Knollmann, Alessandro Bertero, Silvia Marchianò, Kevin C. Cain, Dale Whittington, Faith A. Kalucki, Steven Kattman, Sarah K. Dupras, R. S. Thies, Lauren E. Neidig, Danny El-Nachef, Hiroshi Tsuchida, W. R. MacLellan, D. S. Nakamura, Melissa R. Robinson, Kenta Nakamura, G. J. Weber, Lil Pabon, A. Jayabalu
BackgroundEngraftment arrhythmias (EAs) are observed in large animal studies of intramyocardial transplantation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) for myocardial infarction. Although transient, the risk posed by EA prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fb14e6b2cda2c3ed4e2853292a7f301
https://doi.org/10.1101/2021.02.15.431108
https://doi.org/10.1101/2021.02.15.431108
Publikováno v:
Growth Factors. 18:251-259
GDF-8 is a new member of the TGF-beta superfamily which appears to be a negative regulator of skeletal muscle mass. Factors which regulate the biological activity of GDF-8 have not yet been identified. However, the biological activities of TGF-beta s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ab7d19465fbf45e5776cca1a8cdacb
https://doi.org/10.3109/08977190109029114
https://doi.org/10.3109/08977190109029114
Publikováno v:
Endocrinology. 136:4293-4297
A new member of the transforming growth factor (TGF)-beta superfamily, BMP-9, has recently been identified and shown to be expressed in the developing mouse liver. This report demonstrates that human HepG2 liver tumor cells bind recombinant human BMP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a5c2334fc7a582b08ab79ec2e925d1
https://doi.org/10.1210/endo.136.10.7664647
https://doi.org/10.1210/endo.136.10.7664647
Autor:
R. S. Thies
Publikováno v:
Endocrinology. 130:1318-1324
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed050c02e1885e1aae8ce6bff35dd590
https://doi.org/10.1210/en.130.3.1318
https://doi.org/10.1210/en.130.3.1318
Publikováno v:
Journal of Biological Chemistry. 265:10132-10137
To study the mechanism and role of ligand-dependent endocytosis, we have engineered a mutant insulin receptor that retains its insulin binding and insulin-stimulated tyrosine kinase activities but does not exhibit ligand-induced internalization. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32b3126eefbf0167b334b556804875c6
https://doi.org/10.1016/s0021-9258(19)38789-7
https://doi.org/10.1016/s0021-9258(19)38789-7
Publikováno v:
Diabetes. 39:250-259
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d813b4203083c3819f5c03aaf19be489
https://doi.org/10.2337/diabetes.39.2.250
https://doi.org/10.2337/diabetes.39.2.250
Publikováno v:
Journal of Biological Chemistry. 265:1678-1682
We have recently reported that the expression of an in vitro mutated, kinase-defective insulin receptor (A/K1018) leads to cellular insulin resistance when expressed in Rat 1 fibroblasts. That is, despite the presence of normal numbers of activatable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::795861bdbca280160ce875714df07823
https://doi.org/10.1016/s0021-9258(19)40069-0
https://doi.org/10.1016/s0021-9258(19)40069-0
Publikováno v:
The Journal of biological chemistry. 275(24)
Bone morphogenetic proteins (BMPs) occupy important roles during development serving to direct cells through specific differentiation programs. While several BMPs are essential for embryonic viability, their significance in mediating intercellular co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1444a01c614973c9821610834ce64359
https://pubmed.ncbi.nlm.nih.gov/10849432
https://pubmed.ncbi.nlm.nih.gov/10849432
Publikováno v:
Progress in clinical and biological research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3cc838fedbbaa3197321f74a44836ff5
https://pubmed.ncbi.nlm.nih.gov/8302904
https://pubmed.ncbi.nlm.nih.gov/8302904
Autor:
Vicki Rosen, R S Thies
Publikováno v:
Trends in genetics : TIG. 8(3)
From recent advances in the fields of bone biology and pattern formation, the first clues to our understanding of embryonic skeletal development are beginning to emerge. This complex process involves an integration of spatial patterning and the diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226604d9d0d3b1528a1d930cdba8d680
https://pubmed.ncbi.nlm.nih.gov/1579995
https://pubmed.ncbi.nlm.nih.gov/1579995