Zobrazeno 1 - 10
of 108
pro vyhledávání: '"R S, Shakulov"'
Autor:
A. M. Shcherbakov, N. E. Vavilov, O. E. Andreeva, B. V. Tyaglov, A. S. Mironov, R. S. Shakulov, K. V. Lobanov, S. V. Yarotskiy, A. A. Shtil’
Publikováno v:
Успехи молекулярной онкологии, Vol 4, Iss 1, Pp 60-64 (2017)
The riboside derivative acadesine (5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside) is currently being tested in clinical trials as a promising anti-tumor drug. Intracellular target of acadesine is adenosine monophosphate-activated protein kinas
Externí odkaz:
https://doaj.org/article/27b9b4ec2bbf405bbd22e403365316d7
Publikováno v:
Molecular Biology. 56:572-579
Publikováno v:
Molecular biology. 56(5)
Counteraction of the origin and distribution of multidrug-resistant pathogens responsible for intra-hospital infections is a worldwide issue in medicine. In this brief review, we discuss the results of our recent investigations, which argue that many
Autor:
Evgeny Nudler, Konstantin Shatalin, T. A. Seregina, R. S. Shakulov, Alexander Mironov, Maxim Nagornykh
Publikováno v:
Proceedings of the National Academy of Sciences. 117:23565-23570
l-cysteine is the source of all bacterial sulfurous biomolecules. However, the cytoplasmic level of l-cysteine must be tightly regulated due to its propensity to reduce iron and drive damaging Fenton chemistry. It has been proposed that in Escherichi
Publikováno v:
Russian Journal of Genetics. 55:1573-1576
The effect of E. colicyoA and cydA mutations that diminish the activity of bo' and bd-I terminal oxidases, respectively, on the lifespan of C. elegans nematodes was examined. It was demonstrated that the mean lifespan of the nematodes feeding on the
Publikováno v:
Russian Journal of Genetics. 54:1259-1265
The paradoxical effect of deletion of the Escherichia coli genes cysK and cysM encoding cysteine synthase enzymes has been studied: such cysteine auxotrophs actively degrade the excess of cysteine transported from the medium to form H2S. We have show
Autor:
G. B. Zavilgelsky, R. S. Shakulov
Publikováno v:
Molecular Biology. 52:812-822
Autor:
R. S. Shakulov, G. B. Zavilgelsky
Publikováno v:
Молекулярная биология. 52:935-947
The origin of bioluminescence in living organisms was first mentioned by Charles Darwin (1859) and remains obscure despite significant success achieved over the past decades. Here we discuss the mechanisms of bacterial bioluminescence. We have the ma
Autor:
Alexander Mironov, Gennady Zavilgelsky, R. S. Shakulov, Maxim Nagornykh, Lyly Luhachack, Konstantin Shatalin, Evgeny Nudler, T. A. Seregina, Natalya Korolkova, Vera Kotova, Liubov Errais Lopes
Publikováno v:
Proceedings of the National Academy of Sciences. 114:6022-6027
Endogenous hydrogen sulfide (H 2 S) renders bacteria highly resistant to oxidative stress, but its mechanism remains poorly understood. Here, we report that 3-mercaptopyruvate sulfurtransferase (3MST) is the major source of endogenous H 2 S in Escher
Autor:
S. V. Antonova, R. S. Shakulov, N. F. Rumiantseva, I. I. Malakhova, B. V. Tyaglov, K. V. Lobanov, Alexander Mironov, T. A. Kuvaev, A. A. Pushkov, N. G. Demina, V. D. Krasikov
Publikováno v:
Applied Biochemistry and Microbiology. 52:714-721
Recently published data on the separation and quantification of natural nucleosides and some of their derivatives by thin-layer chromatography on silica gel have been summarized. The use of more than 20 mobile systems for the separation of more than