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Effect of UGT1A1, UGT1A3, DIO1 and DIO2 polymorphisms on L-thyroxine doses required for TSH suppression in patients with differentiated thyroid cancer

Autor: Ana Beatriz Santoro, Ronaldo R. S. Neves, Ricardo M. R. Meirelles, Daniel Bulzico, Guilherme Suarez-Kurtz, Daniela D. Vargens, Daniela Polessa Paula, Luiz Paulo Kowalski, Mateus de Camargo Barros Filho, Claudio J. Struchine, Cencita H. C. N. Pessoa

Publikováno v: British Journal of Clinical Pharmacology. 78:1067-1075

Aim To evaluate the impact of genetic polymorphisms in uridine 5′-glucuronosylytansferases UGT1A1 and UGT1A3 and iodothyronine-deiodinases types 1 and 2 on levothyroxine (T4; 3,5,3′,5′-triiodo-L-thyronine) dose requirement for suppression of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ea0a079567fbd35d9827689efd908a5
https://doi.org/10.1111/bcp.12437

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An approach to provide visual information to support skin wounds therapy

Autor: Levy Aniceto Santana, R. S. Neves, R. Guadagnin, Lourdes Mattos Brasil

Publikováno v: Pattern Recognition and Image Analysis. 24:81-85

Availability of visual information means an effective way to improve specialized work in quite different areas. They enable reality modeling, a faster context analysis, a more successful search for problem solutions, an objective oriented decision ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0e53eb0d1d99d0718720a0c49c97c1f7
https://doi.org/10.1134/s1054661814010052

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Selective increase of angiotensin(1-7) and its receptor in hearts of spontaneously hypertensive rats subjected to physical training

Autor: Anderson J. Ferreira, Ary Gomes Filho, Sílvia R. S. Neves, Lenice Kappes Becker, Elizabeth R.S. Camargos, Marco Fabrício Dias-Peixoto, Sérgio Henrique Sousa Santos, Sérgio Veloso Brant Pinheiro, Hindiael Belchior, Robson A.S. Santos

Publikováno v: Experimental Physiology. 93:589-598

In the present study we investigated the effects of physical training on plasma and cardiac angiotensin(1-7) [Ang(1-7)] levels. In addition, possible changes in expression of the Ang(1-7) Mas receptor in the heart were also evaluated. Normotensive Wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4a48ca021d85fc1c92d750d3b3d80f92
https://doi.org/10.1113/expphysiol.2007.041293

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Selective increase of angiotensin(1-7) and its receptor in hearts of spontaneously hypertensive rats subjected to physical training

Autor: Ary Gomes, Filho, Anderson J, Ferreira, Sérgio Henrique S, Santos, Sílvia R S, Neves, Elizabeth R, Silva Camargos, Lenice K, Becker, Hindiael A, Belchior, Marco Fabricio, Dias-Peixoto, Sérgio V B, Pinheiro, Robson A S, Santos

Publikováno v: Experimental Physiology. 93:589-598

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b504f06f45795fafb7d147a48b6ca532
https://doi.org/10.1113/expphysiol.2007.014293

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Effect of UGT1A1, UGT1A3, DIO1 and DIO2 polymorphisms on L-thyroxine doses required for TSH suppression in patients with differentiated thyroid cancer

Autor: Ana B, Santoro, Daniela D, Vargens, Mateus de Camargo, Barros Filho, Daniel A, Bulzico, Luiz Paulo, Kowalski, Ricardo M R, Meirelles, Daniela P, Paula, Ronaldo R S, Neves, Cencita N, Pessoa, Claudio J, Struchine, Guilherme, Suarez-Kurtz

Publikováno v: British journal of clinical pharmacology. 78(5)

To evaluate the impact of genetic polymorphisms in uridine 5'-glucuronosylytansferases UGT1A1 and UGT1A3 and iodothyronine-deiodinases types 1 and 2 on levothyroxine (T4 ; 3,5,3',5'-triiodo-L-thyronine) dose requirement for suppression of thyrotropin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5dcc55d1c772f4896e0894249741afb8
https://pubmed.ncbi.nlm.nih.gov/24910925

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Association of the UGT1A1-53(TA)n polymorphism with L-thyroxine doses required for thyrotropin suppression in patients with differentiated thyroid cancer

Autor: Carolina Martins do Prado, Elida B. Ojopi, Ronaldo R. S. Neves, Ricardo M. R. Meirelles, Vera L.G. Leal, Guilherme Suarez-Kurtz, Daniela D. Vargens, Pedro A. Gonçalves, Cencita H. C. N. Pessoa, Daniel Bulzico

Publikováno v: Pharmacogenetics and genomics. 21(6)

There is a considerable interindividual variation in L-thyroxine [3,5,3',5'-tetraiodo-l-thyronine (T 4 )] dose required for thyrotropin (thyroid-stimulating hormone) suppression in patients with differentiated thyroid cancer. To investigate whether u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba057f7ff0db1e55e4a7f9b90b8843d
https://pubmed.ncbi.nlm.nih.gov/21317830

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Macrophage populations and cardiac sympathetic denervation during L-NAME-induced hypertension in rats

Autor: S R S, Neves, C R S, Machado, A M T, Pinto, A H D, Borges, F Q, Cunha, E R S, Camargos

Publikováno v: Histology and histopathology. 21(8)

The rat model of hypertension induced by prolonged treatment with Nomega-nitro-L-arginine methyl ester (L-NAME) has been extensively used. However, the effects on cardiac autonomic innervation are unknown. Here, the cardiac sympathetic innervation is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8b4e583ee2d03a203e82b7f48a48ba56
https://pubmed.ncbi.nlm.nih.gov/16691532

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