Zobrazeno 1 - 10
of 44
pro vyhledávání: '"R S, Negrin"'
Publikováno v:
Blood. 92:3318-3327
We have developed culture conditions for the efficient expansion of cytotoxic effector cells from peripheral blood mononuclear cells (PBMNCs) by the timed addition of interferon-γ (IFN-γ), interleukin-2 (IL-2), and the monoclonal antibody (MoAb) OK
Autor:
S H, Bernstein, A P, Nademanee, J M, Vose, G, Tricot, J W, Fay, R S, Negrin, J, DiPersio, G, Rondon, R, Champlin, M J, Barnett, K, Cornetta, G P, Herzig, W, Vaughan, G, Geils, A, Keating, H, Messner, S N, Wolff, K B, Miller, C, Linker, M, Cairo, S, Hellmann, M, Ashby, S, Stryker, R A, Nash
Publikováno v:
Blood. 91:3509-3517
An observational study was conducted at 18 transplant centers in the United States and Canada to characterize the platelet recovery of patients receiving myeloablative therapy and stem cell transplantation and to determine the clinical variables infl
Autor:
J R, Schriber, N J, Chao, G D, Long, R S, Negrin, D K, Tierney, C, Kusnierz-Glaz, K S, Lucas, K G, Blume
Publikováno v:
Blood. 84:1680-1684
Hematopoietic growth factors have been shown to be effective in reducing the period of neutropenia after autologous bone marrow transplantation (BMT). Initial concerns over potential aggravation of graft-versus-host disease (GVHD) and increase in the
Autor:
P H Lu, R S Negrin
Publikováno v:
The Journal of Immunology. 153:1687-1696
Recently, we have reported a novel protocol for the generation of highly efficient cytotoxic effector cells by culturing PBLs in the presence of IFN-gamma, IL-2, mAb against CD3, and IL-1 alpha. We have termed these cultures cytokine-induced killer (
Autor:
N J, Chao, J R, Schriber, K, Grimes, G D, Long, R S, Negrin, C M, Raimondi, S J, Horning, S L, Brown, L, Miller, K G, Blume
Publikováno v:
Blood. 81:2031-2035
Hematopoietic growth factors have been used to accelerate engraftment after bone marrow transplantation and to “mobilize” peripheral blood progenitor cells (PBPC). We report on the data in 85 consecutive patients with Hodgkin's disease who were t
Publikováno v:
Blood. 77:654-660
The polymerase chain reaction (PCR) was used to detect residual malignant disease before and after ex vivo purging with monoclonal antibodies and complement or immunomagnetic treatment of BM samples contaminated with known numbers of t(14;18)-carryin
Publikováno v:
Annals of hematology. 81
Autor:
T M, Cao, C, Kusnierz-Glaz, F, Valone, K E, Stockerl-Goldstein, W W, Hu, L, Johnston, K G, Blume, S, Strober, R S, Negrin
Publikováno v:
Cancer. 91(12)
Acute graft versus host disease (GVHD) remains a major cause of morbidity and mortality after allogeneic hematopoietic cell transplantation. Preclinical studies have suggested that a T-cell subset with a CD4-/CD8- double-negative (DN) T-cell phenotyp
Publikováno v:
Blood. 96(12)
The ability of human gamma delta-T cells to mediate a number of in vitro functions, including innate antitumor and antiviral activity, suggests these cells can be exploited in selected examples of adoptive immunotherapy. To date, however, studies to
Autor:
W W, Hu, G D, Long, K E, Stockerl-Goldstein, L J, Johnston, N J, Chao, R S, Negrin, K G, Blume
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(11)
Dose-intensive chemotherapy appears to be important in the treatment of patients with recurrent solid tumors. Expanding upon our prior experience, we report the results of our most recent approach to administering dose-intensive therapy using four cy