Zobrazeno 1 - 10
of 21
pro vyhledávání: '"R S, Jope"'
Publikováno v:
Translational Psychiatry
Suicide is one of the leading causes of death in the United States, yet it remains difficult to understand the mechanistic provocations and to intervene therapeutically. Stress is recognized as a frequent precursor to suicide. Psychological stress is
Stimulation of death receptors activates the extrinsic apoptotic signaling pathway that leads to cell death. Although many steps of this apoptotic signaling cascade are known, few mechanisms that counterbalance the death signal have been described. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96cf46c7fe4825a43cd064b660621533
https://europepmc.org/articles/PMC2662711/
https://europepmc.org/articles/PMC2662711/
Publikováno v:
Neurochemical research. 26(7)
Muscarinic receptor-mediated changes in protein tyrosine phosphorylation were examined in differentiated human neuroblastoma SH-SY5Y cells. Treatment of differentiated cells with 1 mM carbachol caused rapid increases in the tyrosine phosphorylation o
Publikováno v:
The Journal of biological chemistry. 275(11)
The potential role of glycogen synthase kinase-3beta in modulating apoptosis was examined in human SH-SY5Y neuroblastoma cells. Staurosporine treatment caused time- and concentration-dependent increases in the activities of caspase-3 and caspase-9 bu
Publikováno v:
Journal of neuroscience research. 55(3)
This study's goals were to more fully define the activation of protein tyrosine phosphorylation stimulated by muscarinic receptors, to test if this signaling process is affected by oxidative stress induced by H2O2, and to compare the effects of H2O2
Publikováno v:
The Journal of biological chemistry. 269(27)
We examined the regulation of an amiloride-sensitive sodium conductance expressed in human B lymphoid cells. This conductance was activated by two independent pathways, one involving cyclic adenylyl monophosphate (cAMP)-dependent protein kinase and t
Autor:
R S, Jope
Publikováno v:
Progress in brain research. 98
Publikováno v:
Neurotoxicology. 13(2)
Administration of 0.3% aluminum in drinking water elevated serum aluminum concentrations 8-fold in rats. Further, chronic treatment with aluminum for 2-3 mon, in both developing and adult rats, significantly decreased the levels of MAP-2 in brain, as
Publikováno v:
Neurotoxicology. 13(2)
The influence of seizures on phosphoinositide hydrolysis and protein kinase C activity was measured in rat hippocampus and cerebral cortex, primarily using a model in which generalized convulsive status epilepticus was induced by administration of Li
Autor:
R S, Jope, G V, Johnson
Publikováno v:
Ciba Foundation symposium. 169
Neurochemical responses to chronic oral aluminium administration have been studied in rats. Aluminium (0.3%) was added to drinking water of adult rats for four weeks or longer and weanling rats were given aluminium for eight weeks. Selective cognitiv