Design, Synthesis, Biological Evaluation and Molecular Docking Studies of a New Series of Maleimide Derivatives.

Autor: Eyilcim Ö; Department of Chemistry, Faculty of Arts & Science, Yıldız Technical University, Davutpaşa Campus, 34220, Esenler, Istanbul, Türkiye.; Food Technology Programme, Vocational School of Health Services, Üsküdar University, Carsi Campus, Üsküdar, Istanbul, Türkiye., Günay F; Department of Genetics and Bioengineering, Faculty of Engineering and Natural Sciences, Istanbul Bilgi University, Istanbul, Türkiye., Ng YY; Hogeshooldocent Life Science, Instıtue for Life Science & Chemistry, HU University of Applied Sciences Utrecht, Utrecht, Netherlands., Ulucan Açan Ö; Department of Genetics and Bioengineering, Faculty of Engineering and Natural Sciences, Istanbul Bilgi University, Istanbul, Türkiye., Turgut Z; Department of Chemistry, Faculty of Arts & Science, Yıldız Technical University, Davutpaşa Campus, 34220, Esenler, Istanbul, Türkiye., Günkara ÖT; Department of Chemistry, Faculty of Arts & Science, Yıldız Technical University, Davutpaşa Campus, 34220, Esenler, Istanbul, Türkiye.

Publikováno v: ChemistryOpen [ChemistryOpen] 2024 Sep 23, pp. e202400058. Date of Electronic Publication: 2024 Sep 23.

Integrated Single‐Cell RNA‐seq and ATAC‐seq Reveals Heterogeneous Differentiation of CD4⁺ Naive T Cell Subsets is Associated with Response to Antidepressant Treatment in Major Depressive Disorder.

Autor: Sun, Zuoli¹ (AUTHOR), Zhang, Bowen² (AUTHOR), Zhou, Jingjing¹ (AUTHOR), Luo, Yanting¹ (AUTHOR), Zhu, Xuequan¹ (AUTHOR), Wang, Yaping¹ (AUTHOR), He, Yi¹ (AUTHOR), Zheng, Peng^3,4 (AUTHOR), Zhang, Ling¹ (AUTHOR), Yang, Jian^1,5 (AUTHOR) yangjian@ccmu.edu.cn, Wang, Gang^1,5 (AUTHOR) gangwangdoc@ccmu.edu.cn

Publikováno v: Advanced Science. 8/14/2024, Vol. 11 Issue 30, p1-13. 13p.

Identification of an antiapoptotic protein complex at death receptors

Autor: Mianen Sun, Tong Zhou, Yi-Ping Li, Ling Song, R. S. Jope

Stimulation of death receptors activates the extrinsic apoptotic signaling pathway that leads to cell death. Although many steps of this apoptotic signaling cascade are known, few mechanisms that counterbalance the death signal have been described. W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96cf46c7fe4825a43cd064b660621533
https://europepmc.org/articles/PMC2662711/

Glycogen synthase kinase-3beta facilitates staurosporine- and heat shock-induced apoptosis. Protection by lithium

Autor: G N, Bijur, P, De Sarno, R S, Jope

Publikováno v: The Journal of biological chemistry. 275(11)

The potential role of glycogen synthase kinase-3beta in modulating apoptosis was examined in human SH-SY5Y neuroblastoma cells. Staurosporine treatment caused time- and concentration-dependent increases in the activities of caspase-3 and caspase-9 bu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7b17adb82fd0cd74ae182b430e8f2e1b
https://pubmed.ncbi.nlm.nih.gov/10713065

Stroke Related Brain–Heart Crosstalk: Pathophysiology, Clinical Implications, and Underlying Mechanisms.

Autor: Fan, Xuehui^1,2,3 (AUTHOR), Cao, Jianyang^4,5 (AUTHOR), Li, Mingxia^4,5 (AUTHOR), Zhang, Dechou⁶ (AUTHOR), El‐Battrawy, Ibrahim^7,8 (AUTHOR), Chen, Guiquan⁵ (AUTHOR) chenguiquankangfu@163.com, Zhou, Xiaobo^1,2,3 (AUTHOR) xiaobo.zhou@medma.uni-heidelberg.de, Yang, Guoqiang^2,3,5 (AUTHOR) guoqiang.yang@medma.uni-heidelberg.de, Akin, Ibrahim^2,3 (AUTHOR)

Publikováno v: Advanced Science. 4/10/2024, Vol. 11 Issue 14, p1-17. 17p.