Zobrazeno 1 - 10
of 24
pro vyhledávání: '"R S, Houlston"'
Autor:
J M Allan, N J Sunter, J R Bailey, A R Pettitt, R J Harris, C Pepper, C Fegan, A G Hall, L Deignan, C M Bacon, J C Pointon, R S Houlston, P Broderick, T Mainou-Fowler, G H Jackson, G Summerfield, P A Evans, J C Strefford, A Parker, D Oscier, G Pratt, D J Allsup
Publikováno v:
Leukemia. 24:877-881
A low penetrance risk allele (defined by rs872071) for chronic lymphocytic leukaemia (CLL) has been identified at the interferon regulatory factor 4 (IRF4)|[sol]|multiple myeloma oncogene (MUM1) locus at 6p25.3.1 Given a putative role for IRF4 in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61d7c8917cdd7ab8a1fb3ac29e501f1a
https://doi.org/10.1038/leu.2009.298
https://doi.org/10.1038/leu.2009.298
Autor:
S, Bevan, R S, Houlston
Publikováno v:
Methods in molecular medicine. 41
This chapter details DNA extraction through polymerase chain reaction (PCR) amplification, gel running, allele assignment, and data management so that the genotyping data produced is suitable for use in linkage analysis programs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3cfccbf7b05464c6e7967686b05e9b95
https://pubmed.ncbi.nlm.nih.gov/21374429
https://pubmed.ncbi.nlm.nih.gov/21374429
Autor:
S, Bevan, R S, Houlston
Publikováno v:
Methods in molecular medicine. 41
Many disorders such as celiac disease do not conform to a simple Mendelian model of inheritance and display a complex pattern of inheritance indicative of the interaction of a number of distinct susceptibility genes. Susceptibility to celiac disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bac98fbcb78946906a7524bdbaeffd92
https://pubmed.ncbi.nlm.nih.gov/21374431
https://pubmed.ncbi.nlm.nih.gov/21374431
Autor:
S, Bevan, R S, Houlston
Publikováno v:
Methods in molecular medicine. 41
Linkage analysis in families containing affected individuals can be used to identify the location of disease susceptibility genes. The aim of this chapter is to provide an overview of the molecular methods employed to clone these susceptibility genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::90c41675195b526829a3aca0cd23dea2
https://pubmed.ncbi.nlm.nih.gov/21374430
https://pubmed.ncbi.nlm.nih.gov/21374430
Publikováno v:
Genetic Epidemiology. 7:199-210
Circulating levels of low-density lipoprotein (LDL) vary considerably within and between populations, paralleled by differing coronary heart disease (CHD) mortality rates. We have previously shown that variation in the apolipoprotein (apo) B gene as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88c08453f25ff81c540b6c2f7cd056dc
https://doi.org/10.1002/gepi.1370070304
https://doi.org/10.1002/gepi.1370070304
Autor:
L, Lipton, H J, Thomas, R A, Eeles, R S, Houlston, M, Longmuir, R, Davison, S V, Hodgson, V A, Murday, C G, Norbury, C, Taylor, I P, Tomlinson
Publikováno v:
Familial cancer. 1(3-4)
It is not uncommon for cancer geneticists to be referred families with apparently Mendelian co-inheritance of breast and bowel cancer. Such families present a particular problem as regards the intensity of their screening for these diseases and the u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::438a5327f23f3b3922cb1c722f05147d
https://pubmed.ncbi.nlm.nih.gov/14574178
https://pubmed.ncbi.nlm.nih.gov/14574178
Autor:
L E, Johns, R S, Houlston
Publikováno v:
BJU international. 91(9)
To identify published studies quantifying familial prostate cancer risks in relatives of prostate cancer cases and, by meta-analysis, obtain more precise estimates of familial risk according to the family history.Thirteen case-control and cohort stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::166b29cead1ffb16a2cf335e343942e8
https://pubmed.ncbi.nlm.nih.gov/12780833
https://pubmed.ncbi.nlm.nih.gov/12780833
Autor:
L E, Johns, R S, Houlston
Publikováno v:
Environmental and molecular mutagenesis. 36(3)
Interindividual differences in bladder cancer susceptibility may be partly mediated through polymorphic variability in the metabolism of carcinogens. N-acetyl transferase-2 (NAT2) has been extensively studied as a risk factor in this context, but the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8a88988d7a5b422627ac40ef8c9f733
https://pubmed.ncbi.nlm.nih.gov/11044903
https://pubmed.ncbi.nlm.nih.gov/11044903
Publikováno v:
British journal of haematology. 109(4)
B-cell chronic lymphocytic leukaemia (CLL) is the most common form of leukaemia. To gain insight into the role of inherited factors in the disease, we have conducted a survey of the family histories of 268 CLL patients and have reviewed published fam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f648cca95bf7744ffa0d4e5d2d044c72
https://pubmed.ncbi.nlm.nih.gov/10929032
https://pubmed.ncbi.nlm.nih.gov/10929032