Zobrazeno 1 - 10
of 13
pro vyhledávání: '"R S, Greenfield"'
Publikováno v:
The Journal of Immunology. 150:5241-5251
Granulocyte-macrophage (GM)-CSF is an important hematopoietic cytokine that regulates proliferation and differentiation of macrophages, neutrophils, and eosinophils. In this study, we generated mAb to five synthetic peptides that correspond to region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3d40ebdd5d87f9ca08405bb97549cae
https://doi.org/10.4049/jimmunol.150.12.5241
https://doi.org/10.4049/jimmunol.150.12.5241
Autor:
P A, Trail, D, Willner, J, Knipe, A J, Henderson, S J, Lasch, M E, Zoeckler, M D, TrailSmith, T W, Doyle, H D, King, A M, Casazza, G R, Braslawsky, J, Brown, S J, Hofstead, R S, Greenfield, R A, Firestone, K, Mosure, K F, Kadow, M B, Yang, K E, Hellström, I, Hellström
Publikováno v:
Cancer research. 57(1)
The internalizing anti-Le(y) monoclonal antibody (MAb) BR64 was conjugated to the anticancer drug doxorubicin (DOX) using an acid-labile hydrazone bond to the DOX and either a disulfide or thioether bond to the MAb. The resulting disulfide (BR64-SS-D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c2f4c6c39908d2e124f01054ccecb092
https://pubmed.ncbi.nlm.nih.gov/8988048
https://pubmed.ncbi.nlm.nih.gov/8988048
Autor:
P A, Trail, D, Willner, S J, Lasch, A J, Henderson, R S, Greenfield, D, King, M E, Zoeckler, G R, Braslawsky
Publikováno v:
Cancer research. 52(20)
The anticarcinoma antibody BR64 was conjugated to a doxorubicin derivative, doxorubicin 13-[3-(2-pyridyldithio)propionyl]hydrazone, and the resulting conjugates (BR64-DOX) were evaluated for activity and immunological specificity in vitro and in huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::18e7b6be668738c2e2a95366d27a40ae
https://pubmed.ncbi.nlm.nih.gov/1382845
https://pubmed.ncbi.nlm.nih.gov/1382845
Publikováno v:
Cancer research. 50(20)
Adriamycin (ADM) was chemically coupled to two monoclonal antibodies (MAb) expressed on human B-cell lymphomas. Immunoconjugates were prepared by linking to the MAb an ADM derivative, Adriamycin 13-[3-(2-pyridyldithio)propionyl]hydrazone (ADM-HZN), w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e4b21db7fa281b8caae2af36334b694
https://pubmed.ncbi.nlm.nih.gov/2208123
https://pubmed.ncbi.nlm.nih.gov/2208123
Autor:
R S, Greenfield, T, Kaneko, A, Daues, M A, Edson, K A, Fitzgerald, L J, Olech, J A, Grattan, G L, Spitalny, G R, Braslawsky
Publikováno v:
Cancer research. 50(20)
A novel method for linking Adriamycin (ADM) to monoclonal antibodies is described in which the 13-keto position of the anthracycline is used as the attachment site to the linker arm. A new ADM acylhydrazone derivative, Adriamycin 13-[3-(2-pyridyldith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3813fdc24b38433188d99ad8281524bb
https://pubmed.ncbi.nlm.nih.gov/2208122
https://pubmed.ncbi.nlm.nih.gov/2208122
Publikováno v:
Circulation. 56:181-187
Technetium-99m stannous pyrophosphate (99mTc-PYP) myocardial scintigrams were obtained in 68 patients during acute myocardial infarction (AMI) and at follow-up 15.9 +/- 8.8 weeks later. All patients with AMI had a positive scintigram (2+ or greater);
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ffe3041e6bc672ffd0612d7de5cd06e
https://doi.org/10.1161/01.cir.56.2.181
https://doi.org/10.1161/01.cir.56.2.181
Publikováno v:
The Journal of Immunology. 138:3159-3166
T191, a monoclonal antibody reactive with the T200 common leukocyte antigen, profoundly inhibits an early event(s) associated with alpha-immunoglobulin M (alpha IgM)/T cell replacing factor (TRF) or alpha IgM/recombinant interleukin 1 and 2 (rIL 1 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87d0b93f65f08d6cc72f4b49dd764876
https://doi.org/10.4049/jimmunol.138.10.3159
https://doi.org/10.4049/jimmunol.138.10.3159
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 138(10)
T191, a monoclonal antibody reactive with the T200 common leukocyte antigen, profoundly inhibits an early event(s) associated with alpha-immunoglobulin M (alpha IgM)/T cell replacing factor (TRF) or alpha IgM/recombinant interleukin 1 and 2 (rIL 1 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::53be1e0f43f5dd71aeacddbf3560871a
https://pubmed.ncbi.nlm.nih.gov/2952710
https://pubmed.ncbi.nlm.nih.gov/2952710
Publikováno v:
Virology. 97(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fb8670936e40296036bc576db9f77bb7
https://pubmed.ncbi.nlm.nih.gov/224580
https://pubmed.ncbi.nlm.nih.gov/224580
Autor:
D, Wellner, R S, Greenfield
Publikováno v:
Cancer treatment reports. 63(6)
In vitro studies with L-threonine deaminase purified from sheep liver demonstrated that the enzyme was cytotoxic toward two lines of murine leukemia cells but not toward L cells or normal human fibroblasts. When L-threonine deaminase was injected int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b8a7247d6bcc5bedf18859b3e8a1127
https://pubmed.ncbi.nlm.nih.gov/466649
https://pubmed.ncbi.nlm.nih.gov/466649