Zobrazeno 1 - 10
of 290
pro vyhledávání: '"R S, Gilmour"'
Publikováno v:
European Journal of Histochemistry, Vol 44, Iss 1, Pp 45-50 (2009)
The nucleus of eukaryotic cells contains all the information needed for cell proliferation and differentiation, however the initiation of these programmes are dependent on the signalling pathway elicited by different agonists. The existence of a nucl
Publikováno v:
The Journal of Physiology. 541:581-589
Insulin-like growth factor (IGF)-I has an important role in myogenesis but its developmental regulation in skeletal muscle before birth remains unknown. In other tissues, cortisol modulates IGF gene expression and is responsible for many of the prepa
Publikováno v:
The FASEB Journal. 13:545-552
The developmental and tissue-specific regulation of growth hormone receptor (GHR) mRNA expression is complex and involves alternate leader exon usage. The transcript composition of hepatic GHR mRNA has therefore been determined in fetal sheep during
Autor:
R. S. Gilmour, Julie A. Owens, Karen L. Kind, Fong Lok, K. J. Quinn, J. S. Robinson, Linda Mundy, Phillip C. Owens
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 271:R1632-R1637
Liver contains the highest concentrations of insulin-like growth factor (IGF) I mRNA in adult rats and sheep and is a major source of circulating IGF-I. In rats, inhibition of hepatic IGF-I production by exogenous IGF-I has been reported. In fetal sh
Autor:
Andrew M. Salter, Jennifer M. Pell, John M. Brameld, T.J. Budd, Peter J. Buttery, J. C. Saunders, J.L. Atkinson, R. S. Gilmour
Publikováno v:
Animal Science. 62:555-559
The work described was carried out to study the expression of insulin-like growth factor 1 (IGF-1) and growth hormone-receptor (GHR) mRNA in liver, skeletal muscle and adipose tissue from three breeds of pig with varying growth characteristics. The t
Publikováno v:
Endocrinology. 137:1650-1657
The effects of cortisol on hepatic GH receptor and insulin-like growth factor-I (IGF-I) gene expression were investigated in sheep fetuses during late gestation and after experimental manipulation of plasma cortisol levels by fetal adrenalectomy and
Autor:
M. J. Dauncey, R. S. Gilmour
Publikováno v:
Proceedings of the Nutrition Society. 55:543-559
Publikováno v:
Animal Science. 61:333-339
The growth hormone-insulin-like growth factor (GH-IGF) axis is involved in the control of postnatal growth in all animals studied to date. At birth, blood levels of IGF-1 are low, although levels of GH are high. Thus a switching occurs during the pos
Autor:
J. S. Robinson, K. J. Quinn, P. A. Grant, Phillip C. Owens, Julie A. Owens, Karen L. Kind, R. S. Gilmour, P. E. Walton
Publikováno v:
Journal of Endocrinology. 146:23-34
To determine whether tissue production of the IGFs is altered when fetal growth is retarded, IGF-I and -II mRNAs were measured in tissues of fetal sheep subjected to placental restriction and the relationships between IGF gene expression, circulating
Publikováno v:
Cellular Signalling. 6:481-485