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Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1263:123-132
Hydroxyurea (HU) is an antitumor agent which also induces hemoglobinization during erythroid differentiation. In addition, HU stimulates the synthesis of fetal hemoglobin in sickle cell anemia patients. To further understand its mechanism of action,