Zobrazeno 1 - 10
of 21
pro vyhledávání: '"R S, Bourke"'
Publikováno v:
Progress in clinical and biological research. 361
The work described in this chapter has indicated that improved outcome from an experimental head injury model can be achieved by drugs which are non-diuretic derivatives of loop diuretics, namely indanyl and fluorenyl compounds which are derivatives
Publikováno v:
Acta Neuropathologica. 47:175-181
Histochemical, electron microscopic, and morphometrical techniques were employed in the determination of the effects attributed to K+-induced cerebrocortical swelling on cat cerebrocortical capillary diameter, length, surface area, volume, and minima
Autor:
R. S. Bourke, K. M. Nelson
Publikováno v:
Journal of Neurochemistry. 19:663-685
— The swelling of intact, exposed primate cerebral cortex perfused in vioo under, isosmotic conditions was a linear function of the concentration of K+ in perfusate over the range 25–117 mM. The K+-dependent swelling was manifested throughout the
Autor:
R. S. Bourke, K. M. Nelson
Publikováno v:
Journal of Neurochemistry. 19:1225-1232
— In monkeys we measured the steady-state concentrations of Cl− in endogenous CSF, in artificial CSF (which had equilibrated with the underlying exposed surface of the cerebral cortex but was not in diffusion equilibrium with endogenous CSF), and
Autor:
R. S. Bourke, G. L. Klein
Publikováno v:
Journal of Applied Meteorology. 6:419-424
An instrument for the detailed study of temperature-height profiles within the lower 500 m of the atmosphere is described. The instrument is carried aloft by tethered balloon and, unlike most other tethered sounding instruments, transmits a continual
Autor:
R. S. Bourke, G. L. Klein
Publikováno v:
Journal of Applied Meteorology. 6:707-716
A tethered sonde for obtaining detailed micrometeorological soundings in the lower 500 m of the atmosphere is described. The instrument was developed to be directly compatible with the current audio-modulated radiosonde used extensively in North Amer
Publikováno v:
Cancer research. 35(1)
The mechanism of excretion of methotrexate (MTX) has been investigated in the monkey. Under steady-state conditions of varied plasma levels of MTX, it was determined that MTX was excreted by renal tubular transport as well as by glomerular filtration
Publikováno v:
Cancer research. 36(8)
Entrapment of methotrexate (MTX) plus [3',5', 9(n)-3H]methotrexate into positively charged liposomes greatly alters the subsequent distribution of [3H]MTX in a cynomologous monkey (Macaca irus) after a single i.v. injection ([3H]MTX; refers to total
Publikováno v:
Advances in neurology. 28
Most studies of clinically relevant cerebral edema emphasize the effect of added tissue fluid in white matter on gross distortion with transtentorial and subfalcine brain herniation. Our recent studies on altered tissue fluid compartmentation in cere
Publikováno v:
Surgical neurology. 9(5)
A drop in the arterial PO2 occurring 24 hours after head injury was identified in eight patients. Traditional modes of therapy include administration of supplemental oxygen and provision of an unobstructed airway. The latter proved to be inadequate t