Zobrazeno 1 - 10
of 48
pro vyhledávání: '"R Ryley, Parrish"'
Autor:
Rudhab Bahabry, Rebecca M. Hauser, Richard G. Sánchez, Silvienne Sint Jago, Lara Ianov, Remy J. Stuckey, R. Ryley Parrish, Lawrence Ver Hoef, Farah D. Lubin
Publikováno v:
Neurobiology of Disease, Vol 200, Iss , Pp 106638- (2024)
Temporal lobe epilepsy (TLE) is a type of focal epilepsy characterized by spontaneous recurrent seizures originating from the hippocampus. The epigenetic reprogramming hypothesis of epileptogenesis suggests that the development of TLE is associated w
Externí odkaz:
https://doaj.org/article/38770ea5960840009a2f4a3bb67c2e09
Publikováno v:
Physiological Reports, Vol 11, Iss 15, Pp n/a-n/a (2023)
Abstract We recently reported that strong activation of the optogenetic chloride pump, halorhodopsin leads to a secondary redistribution of K+ ions into the cell, through tonically open, “leak” K+ channels. Here we show that this effect is not un
Externí odkaz:
https://doaj.org/article/c5afedcc324347b09c85827ee6daf979
Autor:
Fred Mulroe, Wei-Hsiang Lin, Connie Mackenzie-Gray Scott, Najat Aourz, Yuen Ngan Fan, Graham Coutts, R. Ryley Parrish, Ilse Smolders, Andrew Trevelyan, Robert C. Wykes, Stuart Allan, Sally Freeman, Richard A. Baines
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 10 (2022)
Externí odkaz:
https://doaj.org/article/3c30c2a06d484e9abf1e1f9a183c7038
Autor:
Samrat Thouta, Matthew G. Waldbrook, Sophia Lin, Arjun Mahadevan, Janette Mezeyova, Maegan Soriano, Pareesa Versi, Samuel J. Goodchild, R. Ryley Parrish
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Voltage-gated sodium channels (Nav) are essential for the initiation and propagation of action potentials in neurons. Of the nine human channel subtypes, Nav1.1, Nav1.2 and Nav1.6 are prominently expressed in the adult central nervous system (CNS). A
Externí odkaz:
https://doaj.org/article/ec0db406855c4da79b69942688086629
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
High-density multi-electrode array (HD-MEA) has enabled neuronal measurements at high spatial resolution to record local field potentials (LFP), extracellular action potentials, and network-wide extracellular recording on an extended spatial scale. W
Externí odkaz:
https://doaj.org/article/e5577a0a17104892b69e9e625bd82eb9
Autor:
Catherine A. Schevon, Steven Tobochnik, Tahra Eissa, Edward Merricks, Brian Gill, R. Ryley Parrish, Lisa M. Bateman, Guy M. McKhann, Jr, Ronald G. Emerson, Andrew J. Trevelyan
Publikováno v:
Neurobiology of Disease, Vol 127, Iss , Pp 303-311 (2019)
The cellular activity underlying human focal seizures, and its relationship to key signatures in the EEG recordings used for therapeutic purposes, has not been well characterized despite many years of investigation both in laboratory and clinical set
Externí odkaz:
https://doaj.org/article/5caebf5e16d746baa98086d07c1ea240
Autor:
Richard G. Sánchez, R. Ryley Parrish, Megan Rich, William M. Webb, Roxanne M. Lockhart, Kazuhito Nakao, Lara Ianov, Susan C. Buckingham, Devin R. Broadwater, Alistair Jenkins, Nihal C. de Lanerolle, Mark Cunningham, Tore Eid, Kristen Riley, Farah D. Lubin
Publikováno v:
Neurobiology of Disease, Vol 124, Iss , Pp 531-543 (2019)
Temporal Lobe Epilepsy (TLE) is frequently associated with changes in protein composition and post-translational modifications (PTM) that exacerbate the disorder. O-linked-β-N-acetyl glucosamine (O-GlcNAc) is a PTM occurring at serine/threonine resi
Externí odkaz:
https://doaj.org/article/e85940fd44384bb39c36e9385352c0cb
Autor:
R. Ryley Parrish, Connie MacKenzie-Gray Scott, Tom Jackson-Taylor, Alex Grundmann, Faye McLeod, Neela K. Codadu, Alexandru Călin, Hannah Alfonsa, Rob C. Wykes, Juha Voipio, Andrew J. Trevelyan
Publikováno v:
The Journal of Neuroscience. 43:685-692
The movement of ions in and out of neurons can exert significant effects on neighboring cells. Here we report several experimentally important consequences of activation of the optogenetic chloride pump, halorhodopsin. We recorded extracellular K+con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::221d91b439c74cf82b768b7a54a6bf41
https://doi.org/10.1523/jneurosci.1141-22.2022
https://doi.org/10.1523/jneurosci.1141-22.2022
Publikováno v:
Data in Brief, Vol 20, Iss , Pp 226-233 (2018)
We provide notes on how to use a graphical user interface (GUI), implemented with MATLAB, for aligning imaging datasets of biological tissue. The original use was for matching two imaging data sets, where one set was taken of the living preparation a
Externí odkaz:
https://doaj.org/article/fe3c9bae03c64a5988fa41018302019d
Publikováno v:
Epilepsy Currents. 23:38-43
Investigations into seizure initiation, in recent years, have focused almost entirely upon alterations of interneuronal function, chloride homeostasis, and extracellular potassium levels. In contrast, little attention has been directed toward a possi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3a2f8b63bc18d4a5932147351b47625
https://doi.org/10.1177/15357597221127163
https://doi.org/10.1177/15357597221127163