Zobrazeno 1 - 10
of 1 059
pro vyhledávání: '"R Rokyta"'
Publikováno v:
Toxins, Vol 16, Iss 4, p 176 (2024)
The evolutionary interplay between predator and prey has significantly shaped the development of snake venom, a critical adaptation for subduing prey. This arms race has spurred the diversification of the components of venom and the corresponding eme
Externí odkaz:
https://doaj.org/article/dc6b34c65f0c48cb8604acb28c6404c1
Autor:
Andrew J. Mason, Mark J. Margres, Jason L. Strickland, Darin R. Rokyta, Mahmood Sasa, Christopher L. Parkinson
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-20 (2020)
Abstract Background Modularity is the tendency for systems to organize into semi-independent units and can be a key to the evolution and diversification of complex biological systems. Snake venoms are highly variable modular systems that exhibit extr
Externí odkaz:
https://doaj.org/article/04a129d68d7349e8b7fdcc83c544e312
Autor:
Mark J. Margres, Kenneth P. Wray, Dragana Sanader, Preston J. McDonald, Lauren M. Trumbull, Austin H. Patton, Darin R. Rokyta
Publikováno v:
Toxins, Vol 13, Iss 11, p 782 (2021)
Ecologically divergent selection can lead to the evolution of reproductive isolation through the process of ecological speciation, but the balance of responsible evolutionary forces is often obscured by an inadequate assessment of demographic history
Externí odkaz:
https://doaj.org/article/c10ec7caf4e340b19010283c077bb483
Autor:
Matthew L. Holding, Vivian C. Trevine, Oleksandr Zinenko, Jason L. Strickland, Rhett M. Rautsaw, Andrew J. Mason, Michael P. Hogan, Christopher L. Parkinson, Felipe G. Grazziotin, Sharlene E. Santana, Mark A. Davis, Darin R. Rokyta
Publikováno v:
Proceedings. Biological sciences. 289(1982)
Traits for prey acquisition form the phenotypic interface of predator–prey interactions. In venomous predators, morphological variation in venom delivery apparatus like fangs and stingers may be optimized for dispatching prey. Here, we determine ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49362165f3569d938d9f2cab2ca87704
https://pubmed.ncbi.nlm.nih.gov/36300520
https://pubmed.ncbi.nlm.nih.gov/36300520
Autor:
Tarek Mohamed Abd El-Aziz, Yucheng Xiao, Jake Kline, Harold Gridley, Alyse Heaston, Klaus D. Linse, Micaiah J. Ward, Darin R. Rokyta, James D. Stockand, Theodore R. Cummins, Luca Fornelli, Ashlee H. Rowe
Publikováno v:
Toxins, Vol 13, Iss 7, p 501 (2021)
The voltage-gated sodium channel Nav1.8 is linked to neuropathic and inflammatory pain, highlighting the potential to serve as a drug target. However, the biophysical mechanisms that regulate Nav1.8 activation and inactivation gating are not complete
Externí odkaz:
https://doaj.org/article/66078cee5d4c41428eff491c6e30d661
Publikováno v:
Toxicon. 210:132-140
As biochemical traits with clear fitness consequences, venoms serve a critical ecological role for the animals that produce them. Understanding how venoms are maintained and regenerated after use will, therefore, provide valuable insight into the eco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80501b3793c726197e097230a40bfdb9
https://doi.org/10.1016/j.toxicon.2022.02.022
https://doi.org/10.1016/j.toxicon.2022.02.022
Autor:
Christopher L. Parkinson, Taylor R. West, Darin R. Rokyta, Javier A. Ortiz-Medina, Rhett M. Rautsaw, Miguel Borja, Juan David Bayona Serrano, Inácio de Loiola Meirelles Junqueira de Azevedo, Marcos Meneses-Millán, Bianca Sabido-Alpuche, Tristan D. Schramer, Gunnar S. Nystrom
Publikováno v:
Toxicon. 205:38-52
Most traditional research on snake venoms has focused on front-fanged snake families (Viperidae, Elapidae, and Atractaspididae). However, venom is now generally accepted as being a much more broadly possessed trait within snakes, including species tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fefd531a1a8a42e931abf6a06b6ceb61
https://doi.org/10.1016/j.toxicon.2021.11.009
https://doi.org/10.1016/j.toxicon.2021.11.009
Autor:
Luciana A. Freitas-de-Sousa, Pedro G. Nachtigall, José A. Portes-Junior, Matthew L. Holding, Gunnar S. Nystrom, Schyler A. Ellsworth, Noranathan C. Guimarães, Emilly Tioyama, Flora Ortiz, Bruno R. Silva, Tobias S. Kunz, Inácio L. M. Junqueira-de-Azevedo, Felipe G. Grazziotin, Darin R. Rokyta, Ana M. Moura-da-Silva
Publikováno v:
Toxins, Vol 12, Iss 12, p 791 (2020)
Ontogenetic changes in venom composition have been described in Bothrops snakes, but only a few studies have attempted to identify the targeted paralogues or the molecular mechanisms involved in modifications of gene expression during ontogeny. In th
Externí odkaz:
https://doaj.org/article/d7b99a24002b49c8ab96caf83a2234b7
Autor:
Richard B. Schonour, Emma M. Huff, Matthew L. Holding, Natalie M. Claunch, Schyler A. Ellsworth, Michael P. Hogan, Kenneth Wray, James McGivern, Mark J. Margres, Timothy J. Colston, Darin R. Rokyta
Publikováno v:
Toxins, Vol 12, Iss 10, p 659 (2020)
Ontogenetic shifts in venom occur in many snakes but establishing their nature as gradual or discrete processes required additional study. We profiled shifts in venom expression from the neonate to adult sizes of two rattlesnake species, the eastern
Externí odkaz:
https://doaj.org/article/1e37456f77ae468ba671cd31287faa0a
Publikováno v:
European Heart Journal. 43
Background/Introduction In patients with heart failure with reduced ejection fraction (HFrEF), QRS duration is of the uttermost importance. Substantial proportion of patients with HFrEF and sufficiently prolonged QRS complex, especially those with le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a984772521081089553ec0e9b2cb3887
https://doi.org/10.1093/eurheartj/ehac544.398
https://doi.org/10.1093/eurheartj/ehac544.398