Zobrazeno 1 - 10
of 1 084
pro vyhledávání: '"R Rand"'
Autor:
Rebecca King, Felix L Struebing, Ying Li, Jiaxing Wang, Allison Ashley Koch, Jessica N Cooke Bailey, Puya Gharahkhani, International Glaucoma Genetics Consortium, NEIGHBORHOOD Consortium, Stuart MacGregor, R Rand Allingham, Michael A Hauser, Janey L Wiggs, Eldon E Geisert
Publikováno v:
PLoS Genetics, Vol 14, Iss 1, p e1007145 (2018)
Central corneal thickness (CCT) is one of the most heritable ocular traits and it is also a phenotypic risk factor for primary open angle glaucoma (POAG). The present study uses the BXD Recombinant Inbred (RI) strains to identify novel quantitative t
Externí odkaz:
https://doaj.org/article/52e401834a3e43f093af65653621c5f4
Autor:
Max A Stockslager, Brian C Samuels, R Rand Allingham, Zoe A Klesmith, Stephen A Schwaner, Craig R Forest, C Ross Ethier
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147020 (2016)
Pathologic changes in intracranial pressure (ICP) are commonly observed in a variety of medical conditions, including traumatic brain injury, stroke, brain tumors, and glaucoma. However, current ICP measurement techniques are invasive, requiring a lu
Externí odkaz:
https://doaj.org/article/1130b6992cba4321be86e0345255f4a1
Publikováno v:
New Journal of Physics, Vol 19, Iss 9, p 093010 (2017)
Modern high performance circular accelerators require sophisticated corrections of nonlinear lattices. The beam betatron tune footprint may cross many resonances, reducing dynamic aperture and causing particle loss. However, if particles cross a reso
Externí odkaz:
https://doaj.org/article/f7c6fafa9a6d4c569a511d50ace195c3
Autor:
Monisha E Nongpiur, Chiea Chuen Khor, Hongyan Jia, Belinda K Cornes, Li-Jia Chen, Chunyan Qiao, K Saidas Nair, Ching-Yu Cheng, Liang Xu, Ronnie George, Do Tan, Khaled Abu-Amero, Shamira A Perera, Mineo Ozaki, Takanori Mizoguchi, Yasuo Kurimoto, Sancy Low, Liza-Sharmini A Tajudin, Ching-Lin Ho, Clement C Y Tham, Ileana Soto, Paul T K Chew, Hon-Tym Wong, Balekudaru Shantha, Masako Kuroda, Essam A Osman, Guangxian Tang, Sujie Fan, Hailin Meng, Hua Wang, Bo Feng, Victor H K Yong, Serena M L Ting, Yang Li, Ya-Xing Wang, Zheng Li, Raghavan Lavanya, Ren-Yi Wu, Ying-Feng Zheng, Daniel H Su, Seng-Chee Loon, Vernon K Y Yong, R Rand Allingham, Michael A Hauser, Nagaswamy Soumittra, Vedam L Ramprasad, Naushin Waseem, Azhany Yaakub, Kee-Seng Chia, Govindasamy Kumaramanickavel, Tina T Wong, Alicia C How, Tran Nguyen Bich Chau, Cameron P Simmons, Jin-Xin Bei, Yi-Xin Zeng, Shomi S Bhattacharya, Mingzhi Zhang, Donald T Tan, Yik-Ying Teo, Saleh A Al-Obeidan, Do Nhu Hon, E-Shyong Tai, Seang-Mei Saw, Paul J Foster, Lingam Vijaya, Jost B Jonas, Tien-Yin Wong, Simon W M John, Chi-Pui Pang, Eranga N Vithana, Ningli Wang, Tin Aung
Publikováno v:
PLoS Genetics, Vol 10, Iss 3, p e1004089 (2014)
Anterior chamber depth (ACD) is a key anatomical risk factor for primary angle closure glaucoma (PACG). We conducted a genome-wide association study (GWAS) on ACD to discover novel genes for PACG on a total of 5,308 population-based individuals of As
Externí odkaz:
https://doaj.org/article/877cd4c646ac4df2b2fcf327072cf4be
Autor:
Megan Ulmer Carnes, Yangfan P Liu, R Rand Allingham, Benjamin T Whigham, Shane Havens, Melanie E Garrett, Chunyan Qiao, NEIGHBORHOOD Consortium Investigators, Nicholas Katsanis, Janey L Wiggs, Louis R Pasquale, Allison Ashley-Koch, Edwin C Oh, Michael A Hauser
Publikováno v:
PLoS Genetics, Vol 10, Iss 5, p e1004372 (2014)
Glaucoma is a leading cause of blindness worldwide. Primary open-angle glaucoma (POAG) is the most common subtype and is a complex trait with multigenic inheritance. Genome-wide association studies have previously identified a significant association
Externí odkaz:
https://doaj.org/article/09a059fa35e943d39c6a161436730c9a
Autor:
Joel A Dietz, Margaret E Maes, Shuang Huang, Brian S Yandell, Cassandra L Schlamp, Angela D Montgomery, R Rand Allingham, Michael A Hauser, Robert W Nickells
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93564 (2014)
The Rgcs1 quantitative trait locus, on mouse chromosome 5, influences susceptibility of retinal ganglion cells to acute damage of the optic nerve. Normally resistant mice (DBA/2J) congenic for the susceptible allele from BALB/cByJ mice exhibit suscep
Externí odkaz:
https://doaj.org/article/9f5b02ad14dc4ceba5cfe49d6a15feba
Autor:
Janey L Wiggs, Brian L Yaspan, Michael A Hauser, Jae H Kang, R Rand Allingham, Lana M Olson, Wael Abdrabou, Bao J Fan, Dan Y Wang, Wendy Brodeur, Donald L Budenz, Joseph Caprioli, Andrew Crenshaw, Kristy Crooks, Elizabeth Delbono, Kimberly F Doheny, David S Friedman, Douglas Gaasterland, Terry Gaasterland, Cathy Laurie, Richard K Lee, Paul R Lichter, Stephanie Loomis, Yutao Liu, Felipe A Medeiros, Cathy McCarty, Daniel Mirel, Sayoko E Moroi, David C Musch, Anthony Realini, Frank W Rozsa, Joel S Schuman, Kathleen Scott, Kuldev Singh, Joshua D Stein, Edward H Trager, Paul Vanveldhuisen, Douglas Vollrath, Gadi Wollstein, Sachiko Yoneyama, Kang Zhang, Robert N Weinreb, Jason Ernst, Manolis Kellis, Tomohiro Masuda, Don Zack, Julia E Richards, Margaret Pericak-Vance, Louis R Pasquale, Jonathan L Haines
Publikováno v:
PLoS Genetics, Vol 8, Iss 4, p e1002654 (2012)
Optic nerve degeneration caused by glaucoma is a leading cause of blindness worldwide. Patients affected by the normal-pressure form of glaucoma are more likely to harbor risk alleles for glaucoma-related optic nerve disease. We have performed a meta
Externí odkaz:
https://doaj.org/article/c0f601961fb1441ea4c7117937edd651
Autor:
David Fleischman, John P Berdahl, Jana Zaydlarova, Sandra Stinnett, Michael P Fautsch, R Rand Allingham
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52664 (2012)
Clinical studies implicate low cerebrospinal fluid pressure (CSFP) or a high translaminar pressure difference in the pathogenesis of primary open angle glaucoma (POAG) and normal tension glaucoma (NTG). This study was performed to examine the effect
Externí odkaz:
https://doaj.org/article/f71611f90b85431bac02b032a35fd732
Autor:
Yi-Ju Li, Mollie A Minear, Jacqueline Rimmler, Bei Zhao, Elmer Balajonda, Michael A Hauser, R Rand Allingham, Allen O Eghrari, S Amer Riazuddin, Nicholas Katsanis, John D Gottsch, Simon G Gregory, Gordon K Klintworth, Natalie A Afshari
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18044 (2011)
Fuchs endothelial corneal dystrophy (FECD) is a common, late-onset disorder of the corneal endothelium. Although progress has been made in understanding the genetic basis of FECD by studying large families in which the phenotype is transmitted in an
Externí odkaz:
https://doaj.org/article/6728000597c34a7097af38dd6639c715