Zobrazeno 1 - 10
of 19
pro vyhledávání: '"R R, Holson"'
Publikováno v:
Psychopharmacology. 127:187-194
Publikováno v:
Toxicological Sciences. 19:545-554
Publikováno v:
Neurotoxicology. 18(2)
To investigate the neurobehavioral and developmental effects of the mycotoxin, FB1, Sprague-Dawley rats were treated with FB1 on gestational days 13-20. In Experiment 1, FB1 was obtained from culture material and pregnant rats were gavaged with 0, 0.
Autor:
Z, Binienda, R R, Holson, F X, Chen, E, Oriaku, C S, Kim, T J, Flynn, W, Slikker, M G, Paule, R J, Feuers, S A, Ferguson
Publikováno v:
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 14(4)
The effects of acute perinatal ischemia-hypoxia on fetal liver and brain energy metabolism, fetal brain total free fatty acid concentration and subsequent offspring behavior were investigated in rats. Ischemia-hypoxia was induced at term either by li
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 268(3)
The depletion of striatal dopamine (DA) that can occur after methamphetamine (METH) administration has been linked to METH-induced hyperthermia. The relationship between METH-induced hyperthermia, neurotoxicity (striatal DA depletions) and compounds
Publikováno v:
Behavioral neuroscience. 107(6)
This study was prompted by reports of functionally normal humans with micrencephaly or cortical hypoplasia. Methylazoxymethanol acetate (MAM) treatment, which induces micrencephaly in rats, was administered by injection (20 mg/kg) on gestational day
Publikováno v:
Brain research. Developmental brain research. 73(1)
Phencyclidine (PCP) inhibits the uptake of the neurotransmitter dopamine (DA), and blocks N-methyl-D-aspartate (NMDA) receptor-regulated ion channels. PCP also binds to sigma receptors in vivo and in vitro in rat brain. Prolonged exposure to PCP in a
Publikováno v:
Annali dell'Istituto superiore di sanita. 29(1)
In an attempt to further develop basic principles to guide research in neurobehavioral teratology, six experiments were conducted to examine the effects of prenatal haloperidol (a D2 dopamine antagonist) exposure on striatal D1 and D2 binding sites.
Publikováno v:
Journal of craniofacial genetics and developmental biology. 12(4)
It is unknown whether orofacial clefting, one consequence of teratogenic exposure, results from a direct interaction between the teratogen and the embryonic palate, or indirectly from maternal alterations caused by the teratogen. In the current study
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 260(2)
When male rats were injected four times (once every 2 hr) with 5 mg/kg methamphetamine (METH) at an environmental temperature of 23 degrees C, transient changes occurred in the levels of striatal dopamine (DA) and the regulation of striatal DA releas