Zobrazeno 1 - 10
of 128
pro vyhledávání: '"R R, Dalvi"'
Autor:
R. R. Dalvi, D. P. Deoras
Publikováno v:
Acta Pharmacologica et Toxicologica. 58:38-42
Thiram, tetramethylthiuram disulfide, is used extensively as an agricultural fungicide whose toxicity is largely dependent on its metabolism. The following experiments were carried out to investigate whether carbon disulfide (CS2) is a metabolic prod
Publikováno v:
Pharmacology & Toxicology. 76:289-291
Publikováno v:
Veterinary and human toxicology. 42(4)
We examined the effect of 3-methylcholanthrene (3-MC) on the liver toxicity of sanguinarine in mice. Administration of 10 mg sanguinarine/kg bw ip to male mice resulted in significant decreases in liver glutathione and P450 enzymes activities, and in
Publikováno v:
Veterinary research communications. 21(5)
A single intraperitoneal dose (25 mg/kg) of gossypol given to male Sprague-Dawley rats caused marked changes in the activity of the hepatic and serum gamma-glutamyltransferase (GGT) and microsomal monooxygenases. The GGT activity in liver homogenate,
Autor:
J K, Vodela, R R, Dalvi
Publikováno v:
Veterinary and human toxicology. 39(1)
This study was conducted to determine and compare the activities of glutathione-S-transferase (GST) in red blood cells of cattle, horses, pigs, goats, dogs, rabbits, rats and mice. The highest GST activity was found in mouse red blood cells followed
Autor:
J K, Vodela, R R, Dalvi
Publikováno v:
Veterinary and human toxicology. 37(1)
Rats and chickens were given single oral doses of 50 mg chlorpyrifos/kg to compare toxic effects in these 2 species. Oral administration resulted in decreased cytochrome P-450 and aminopyrine N-demethylase activities and increased cytosolic glutathio
Autor:
R R, Dalvi
Publikováno v:
Veterinary and human toxicology. 34(3)
Monensin administered ip to male rats at a dosage of 2.5 mg/kg/d for 3 consecutive days did not change the liver levels of glutathione, but depressed significantly the amount of cytochrome P-450 and the activities of aniline hydroxylase and a cytosol
Publikováno v:
Veterinary and human toxicology. 33(6)
Intraperitoneal administration of 10 mg fenbendazole/kg bw daily for 5 d caused no significant alterations in the activities of hepatic microsomal drug-metabolizing enzymes viz aminopyrine N-demethylase, aniline hydroxylase and cytosolic glutathione
Autor:
P. S. Dalvi, R. R. Dalvi
Publikováno v:
Drug and chemical toxicology. 14(1-2)
An i.p. administration of rats with piperine (100 mg/kg) and piperonyl butoxide (400 mg/kg) produced a significant decrease in hepatic cyotchrome P-450, and activities of benzphetamine N-demethylase, aminopyrine N-demethylase and aniline hydroxylase
Autor:
Zhao R; State Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, Chemistry and Biomedicine Innovation Center, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210023, China., Chen Y; State Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, Chemistry and Biomedicine Innovation Center, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210023, China., Liang Y; State Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, Chemistry and Biomedicine Innovation Center, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210023, China.
Publikováno v:
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Jul 29; Vol. 63 (31), pp. e202400020. Date of Electronic Publication: 2024 Jun 25.