Výsledky vyhledávání

Second stage of a genome scan of schizophrenia: study of five positive regions in an expanded sample

Autor: B J, Mowry, K R, Ewen, D J, Nancarrow, D P, Lennon, D A, Nertney, H L, Jones, M S, O'Brien, C E, Thornley, M K, Walters, R R, Crowe, J M, Silverman, J, Endicott, L, Sharpe, N K, Hayward, M M, Gladis, S J, Foote, D F, Levinson

Publikováno v: American journal of medical genetics. 96(6)

In a previous genome scan of 43 schizophrenia pedigrees, nonparametric linkage (NPL) scores with empirically derived pointwise P-values less than 0.01 were observed in two regions (chromosomes 2q12-13 and 10q23) and less than 0.05 in three regions (4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::31df1597e929b69dc9637b3d5e1fa106
https://pubmed.ncbi.nlm.nih.gov/11121199

Zobrazit plný text záznamu

Family-based study of the association of the dopamine D2 receptor gene (DRD2) with habitual smoking

Autor: L J, Bierut, J P, Rice, H J, Edenberg, A, Goate, T, Foroud, C R, Cloninger, H, Begleiter, P M, Conneally, R R, Crowe, V, Hesselbrock, T K, Li, J I, Nurnberger, B, Porjesz, M A, Schuckit, T, Reich

Publikováno v: American journal of medical genetics. 90(4)

A recent study showed an association between the dopamine D2 receptor gene (DRD2) and smoking. The purpose of this study was to determine if the familial transmission of smoking is linked to variation at the DRD2 locus in a genetically informative sa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4ac6f2b1839837baa1d6f77b732f02ef
https://pubmed.ncbi.nlm.nih.gov/10710227

Zobrazit plný text záznamu

Heritability of BDNF alleles and their effect on brain morphology in schizophrenia

Autor: T H, Wassink, J J, Nelson, R R, Crowe, N C, Andreasen

Publikováno v: American journal of medical genetics. 88(6)

Accumulating evidence suggests that disturbed brain development may play a role in the etiology of schizophrenia, and that the illness is, to a significant degree, heritable. We therefore investigated brain derived neurotrophic factor (BDNF), a neuro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::88b5d5a1cdae44b5746e868e1aa2e1fe
https://pubmed.ncbi.nlm.nih.gov/10581496

Zobrazit plný text záznamu

Follow-up study on a susceptibility locus for schizophrenia on chromosome 6q

Autor: M, Martinez, L R, Goldin, Q, Cao, J, Zhang, A R, Sanders, D J, Nancarrow, J M, Taylor, D F, Levinson, A, Kirby, R R, Crowe, N C, Andreasen, D W, Black, J M, Silverman, D P, Lennon, D A, Nertney, D M, Brown, B J, Mowry, E S, Gershon, P V, Gejman

Publikováno v: American journal of medical genetics. 88(4)

Evidence for suggestive linkage to schizophrenia with chromosome 6q markers was previously reported from a two-stage approach. Using nonparametric affected sib pairs (ASP) methods, nominal p-values of 0.00018 and 0.00095 were obtained in the screenin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::13a80dfd98fa94cf91c9fdbb3f180a44
https://pubmed.ncbi.nlm.nih.gov/10402499

Zobrazit plný text záznamu

The life-time rates of three major mood disorders and four major anxiety disorders in alcoholics and controls

Autor: M A, Schuckit, J E, Tipp, K K, Bucholz, J I, Nurnberger, V M, Hesselbrock, R R, Crowe, J, Kramer

Publikováno v: Addiction (Abingdon, England). 92(10)

While psychiatric symptoms are common in the general population and even more prevalent in alcoholics, their clinical implications are not clear. The goal of this study was to establish the life-time rates of several independent and concurrent mood a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b22cd3bd50eca0934dd6018ba9de8868
https://pubmed.ncbi.nlm.nih.gov/9489046

Zobrazit plný text záznamu

Missense mutation of the cholecystokinin B receptor gene: lack of association with panic disorder

Autor: T, Kato, Z W, Wang, T, Zoega, R R, Crowe

Publikováno v: American journal of medical genetics. 67(4)

Cholecystokinin tetrapeptide (CCK4) is known to induce panic attacks in patients with panic disorder at a lower dose than in normal controls. Therefore, the cholecystokinin B (CCKB) receptor gene is a candidate gene for panic disorder. We searched fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::39d23d77476c5a7d171f0a1260117798
https://pubmed.ncbi.nlm.nih.gov/8837709

Zobrazit plný text záznamu

The application of genetic methods to the study of disease associations in psychiatry

Autor: R R, Crowe

Publikováno v: The Psychiatric clinics of North America. 13(4)

The problem of multiple diagnoses in the same patient is a very real one in psychiatry. Theoretical causes of disease associations are reviewed and illustrated with examples from a variety of psychiatric conditions. These include Huntington's disease

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::597d0e492cc0fc8c2c5a75fc568d012b
https://pubmed.ncbi.nlm.nih.gov/2281007

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání