Zobrazeno 1 - 10
of 470
pro vyhledávání: '"R Pine"'
Autor:
Vrushank Bhatt, Taijin Lan, Wenping Wang, Jerry Kong, Eduardo Cararo Lopes, Jianming Wang, Khoosheh Khayati, Akash Raju, Michael Rangel, Enrique Lopez, Zhixian Sherrie Hu, Xuefei Luo, Xiaoyang Su, Jyoti Malhotra, Wenwei Hu, Sharon R. Pine, Eileen White, Jessie Yanxiang Guo
Publikováno v:
Cell Death and Disease, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract LKB1 and KRAS are the third most frequent co-mutations detected in non-small cell lung cancer (NSCLC) and cause aggressive tumor growth. Unfortunately, treatment with RAS-RAF-MEK-ERK pathway inhibitors has minimal therapeutic efficacy in LKB
Externí odkaz:
https://doaj.org/article/5290d1394aaa48838b42a4b8a39fdce8
Autor:
Andrea M Chambers, Kyle B Lupo, Jiao Wang, Jingming Cao, Sagar Utturkar, Nadia Lanman, Victor Bernal-Crespo, Shadia Jalal, Sharon R Pine, Sandra Torregrosa-Allen, Bennett D Elzey, Sandro Matosevic
Publikováno v:
eLife, Vol 11 (2022)
Immunometabolic reprogramming due to adenosine produced by CD73 (encoded by the 5’-ectonucleotidase gene NT5E) is a recognized immunosuppressive mechanism contributing to immune evasion in solid tumors. Adenosine is not only known to contribute to
Externí odkaz:
https://doaj.org/article/97d6c81764a042458eef5e324c28f106
Autor:
Khadijah A. Mitchell, Noah Nichols, Wei Tang, Jennifer Walling, Holly Stevenson, Marbin Pineda, Roxana Stefanescu, Daniel C. Edelman, Andrew T. Girvin, Adriana Zingone, Sanju Sinha, Elise Bowman, Emily L. Rossi, Rony F. Arauz, Yuelin Jack Zhu, Justin Lack, Elizabeth Weingartner, Joshua J. Waterfall, Sharon R. Pine, John Simmons, Paul Meltzer, Bríd M. Ryan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
Lung cancer etiology has largely been studied in homogenous populations of European descent. Here, targeted sequencing in African American lung adenocarcinomas finds significantly higher prevalence of PTPRTand JAK2 mutations, validated independently
Externí odkaz:
https://doaj.org/article/cad556f170ba4c32bd112c041c7993c8
Publikováno v:
Heliyon, Vol 7, Iss 2, Pp e06234- (2021)
Prosthetic eyes are currently manufactured using Poly(methyl methacrylate) (PMMA) which is not an ideal material because it is hydrophobic. While significant research has investigated the benefits of hydrophilic materials for contact lenses, no such
Externí odkaz:
https://doaj.org/article/77871d923d844d7f9488cb6bfc796f51
Autor:
Allison R. Pine, Stefano M. Cirigliano, Richa Singhania, James Nicholson, Bárbara da Silva, Christina S. Leslie, Howard A. Fine
Publikováno v:
Cancer Research. 83:1581-1595
The tumor microenvironment is necessary for recapitulating the intratumoral heterogeneity and cell state plasticity found in human primary glioblastoma (GBM). Conventional models do not accurately recapitulate the spectrum of GBM cellular states, hin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfcf185a4ba3ba604b7d0a5e99ec9567
https://doi.org/10.1158/0008-5472.can-22-2872
https://doi.org/10.1158/0008-5472.can-22-2872
Autor:
Alexander C. Rokohl, Nicola S. Pine, Werner Adler, Lisa A. K. Bartenschlager, Philomena A. Wawer Matos, Marc Trester, Keith R. Pine, Timo-Kolja Pförtner, Ludwig M. Heindl
Publikováno v:
Current Eye Research. 48:11-17
To investigate general and electronic health literacy (HL) levels in prosthetic eye wearing patients, to define factors associated with reduced HL, and to identify a potential healthcare gap.In this prospective cross-sectional study 148 prosthetic ey
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c61faf62998ce7a300fc1a2f0751a65a
https://doi.org/10.1080/02713683.2022.2141783
https://doi.org/10.1080/02713683.2022.2141783
Autor:
Mijung Kwon, Genesaret Rubio, Haitao Wang, Gregory Riedlinger, Asha Adem, Hua Zhong, Daniel Slegowski, Louisa Post-Zwicker, Anshruta Chidananda, David S. Schrump, Sharon R. Pine, Steven K. Libutti
Publikováno v:
Cancer Research Communications. 2:1197-1213
Lung adenocarcinoma (LUAD) is the major subtype in lung cancer, and cigarette smoking is essentially linked to its pathogenesis. We show that downregulation of Filamin A interacting protein 1-like (FILIP1L) is a driver of LUAD progression. Cigarette
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd3003953980d758902a017f2a7195f3
https://doi.org/10.1158/2767-9764.crc-22-0233
https://doi.org/10.1158/2767-9764.crc-22-0233
Autor:
Howard A. Fine, Christina S. Leslie, Bárbara da Silva, James Nicholson, Richa Singhania, Stefano M. Cirigliano, Allison R. Pine
Supplementary Table (Table S1) and Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::511301121068c10ef80413340aa28b44
https://doi.org/10.1158/0008-5472.22820155
https://doi.org/10.1158/0008-5472.22820155
Autor:
Howard A. Fine, Christina S. Leslie, Bárbara da Silva, James Nicholson, Richa Singhania, Stefano M. Cirigliano, Allison R. Pine
Supplementary Figures (Figures S1-S5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28a98d41fc6378d7d17f7c4b36c3eb39
https://doi.org/10.1158/0008-5472.22746996.v1
https://doi.org/10.1158/0008-5472.22746996.v1
Autor:
Howard A. Fine, Christina S. Leslie, Bárbara da Silva, James Nicholson, Richa Singhania, Stefano M. Cirigliano, Allison R. Pine
The tumor microenvironment is necessary for recapitulating the intratumoral heterogeneity and cell state plasticity found in human primary glioblastoma (GBM). Conventional models do not accurately recapitulate the spectrum of GBM cellular states, hin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a46a448f8ea6c32553ca2fd3db3155b
https://doi.org/10.1158/0008-5472.c.6628632.v1
https://doi.org/10.1158/0008-5472.c.6628632.v1