Zobrazeno 1 - 10
of 423
pro vyhledávání: '"R Peinado"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Neuronal aging may be, in part, related to a change in DNA methylation. Thus, methyl donors, like folate and methionine, may play a role in cognitive changes associated to neuronal aging. To test the role of these metabolites, we performed s
Externí odkaz:
https://doaj.org/article/a44a16c88c7a4280bfc4093a52447d18
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Externí odkaz:
https://doaj.org/article/29e577fdc4544d72ab43587ffdf178f1
Autor:
G. Gutiérrez Gutiérrez, J. Díaz-Manera, M. Almendrote, S. Azriel, J. Eulalio Bárcena, P. Cabezudo García, A. Camacho Salas, C. Casanova Rodríguez, A.M. Cobo, P. Díaz Guardiola, R. Fernández-Torrón, M.P. Gallano Petit, P. García Pavía, M. Gómez Gallego, A.J. Gutiérrez Martínez, I. Jericó, S. Kapetanovic García, A. López de Munaín Arregui, L. Martorell, G. Morís de la Tassa, R. Moreno Zabaleta, J.L. Muñoz-Blanco, J. Olivar Roldán, S.I. Pascual Pascual, R. Peinado Peinado, H. Pérez, J.J. Poza Aldea, M. Rabasa, A. Ramos, A. Rosado Bartolomé, M.Á. Rubio Pérez, J.A. Urtizberea, G. Zapata-Wainberg, E. Gutiérrez-Rivas
Publikováno v:
Neurología, Vol 35, Iss 3, Pp 185-206 (2020)
Resumen: Antecedentes y objetivos: La enfermedad de Steinert o distrofia miotónica tipo 1 (DM1), (OMIM 160900) es la miopatía más prevalente en el adulto. Es una enfermedad multisistémica con alteración de prácticamente todos los órganos y tej
Externí odkaz:
https://doaj.org/article/9d1caa957ea848ef9d4dc050fb45812a
Autor:
G. Gutiérrez Gutiérrez, J. Díaz-Manera, M. Almendrote, S. Azriel, J. Eulalio Bárcena, P. Cabezudo García, A. Camacho Salas, C. Casanova Rodríguez, A.M. Cobo, P. Díaz Guardiola, R. Fernández-Torrón, M.P. Gallano Petit, P. García Pavía, M. Gómez Gallego, A.J. Gutiérrez Martínez, I. Jericó, S. Kapetanovic García, A. López de Munaín Arregui, L. Martorell, G. Morís de la Tassa, R. Moreno Zabaleta, J.L. Muñoz-Blanco, J. Olivar Roldán, S.I. Pascual Pascual, R. Peinado Peinado, H. Pérez, J.J. Poza Aldea, M. Rabasa, A. Ramos, A. Rosado Bartolomé, M.Á. Rubio Pérez, J.A. Urtizberea, G. Zapata-Wainberg, E. Gutiérrez-Rivas
Publikováno v:
Neurología (English Edition), Vol 35, Iss 3, Pp 185-206 (2020)
Background and objectives: Steinert's disease or myotonic dystrophy type 1 (MD1), (OMIM 160900), is the most prevalent myopathy in adults. It is a multisystemic disorder with dysfunction of virtually all organs and tissues and a great phenotypical va
Externí odkaz:
https://doaj.org/article/196b7b9402d34ccd938bfec8b69442c1
Autor:
M. Carmen Navarro-Ruiz, M. Carmen Soler-Vázquez, Alberto Díaz-Ruiz, Juan R. Peinado, Andrea Nieto Calonge, Julia Sánchez-Ceinos, Carmen Tercero-Alcázar, Jaime López-Alcalá, Oriol A. Rangel-Zuñiga, Antonio Membrives, José López-Miranda, María M. Malagón, Rocío Guzmán-Ruiz
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3032 (2022)
Background: Obesity is characterized by adipose tissue dysregulation and predisposes individuals to insulin resistance and type 2 diabetes. At the molecular level, adipocyte dysfunction has been linked to obesity-triggered oxidative stress and protei
Externí odkaz:
https://doaj.org/article/97eb2fdde8284d3787e4e5b17753fe6d
Autor:
Cristina M. Pedrero-Prieto, Alicia Flores-Cuadrado, Daniel Saiz-Sánchez, Isabel Úbeda-Bañón, Javier Frontiñán-Rubio, Francisco J. Alcaín, Lourdes Mateos-Hernández, José de la Fuente, Mario Durán-Prado, Margarita Villar, Alino Martínez-Marcos, Juan R. Peinado
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-16 (2019)
Abstract Background Intracerebral inoculation of extracts from post-mortem human Alzheimer’s disease brains into mice produces a prion-like spreading effect of amyloid-β. The differences observed between these extracts and the synthetic peptide, i
Externí odkaz:
https://doaj.org/article/214a4010500d4f259b5f7b96dc6215c3
Autor:
Cristina M. Pedrero-Prieto, Javier Frontiñán-Rubio, Francisco J. Alcaín, Mario Durán-Prado, Juan R. Peinado, Yoana Rabanal-Ruiz
Publikováno v:
Diagnostics, Vol 11, Iss 9, p 1655 (2021)
The fact that cerebrospinal fluid (CSF) deeply irrigates the brain together with the relative simplicity of sample extraction from patients make this biological fluid the best target for biomarker discovery in neurodegenerative diseases. During the l
Externí odkaz:
https://doaj.org/article/df922e9745834e74ad5875429be3e833
Autor:
Charlène Delestre-Delacour, Ophélie Carmon, Fanny Laguerre, Catherine Estay-Ahumada, Maïté Courel, Salah Elias, Lydie Jeandel, Margarita Villar Rayo, Juan R. Peinado, Lucie Sengmanivong, Stéphane Gasman, Evelyne Coudrier, Youssef Anouar, Maité Montero-Hadjadje
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Hormone secretion relies on secretory granules which store hormones in endocrine cells and release them upon cell stimulation. The molecular events leading to hormone sorting and secretory granule formation at the level of the TGN are still
Externí odkaz:
https://doaj.org/article/c658314d9f454de6b972e5ddac4717e6
Akademický článek
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Autor:
Juan R. Peinado, Kriti Chaplot, Timothy S. Jarvela, Edward M. Barbieri, James Shorter, Iris Lindberg
Publikováno v:
ACS Chem Neurosci
As neurons age, protein homeostasis becomes less efficient, resulting in misfolding and aggregation. Chaperone proteins perform vital functions in the maintenance of cellular proteostasis, and chaperone-based therapies that promote sequestration of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c31f44f2ea11339d1d9543e2be63c7c
https://doi.org/10.1021/acschemneuro.2c00156
https://doi.org/10.1021/acschemneuro.2c00156