Zobrazeno 1 - 10
of 23
pro vyhledávání: '"R Patrick Weitzel"'
Autor:
Naoya Uchida, R Patrick Weitzel, Anna Shvygin, Luke P Skala, Lydia Raines, Aylin C Bonifacino, Allen E Krouse, Mark E Metzger, Robert E Donahue, John F Tisdale
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Reduced intensity conditioning (RIC) is desirable for hematopoietic stem cell (HSC) gene therapy applications. However, low gene marking was previously observed in gene therapy trials, suggesting that RIC might be insufficient for (i) opening niches
Externí odkaz:
https://doaj.org/article/b2866a0cb9114dddbfe8675ea28d0e4a
Autor:
Greene Donald Royster, Justine C. Harris, Amanda Nelson, Ryan J. Heitmann, John F. Tisdale, Alan H. DeCherney, R. Patrick Weitzel, Yessenia Castro, Erin F. Wolff
Publikováno v:
Reprod Sci
There are few treatments for patients with recurrent pregnancy loss (RPL) or recurrent implantation failure (RIF). Women with RPL and unexplained infertility have lower T regulatory cell (T(reg)) expression when compared to fertile controls. A murine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f65d301266cd69721f268e8f9b7e18b9
https://doi.org/10.1177/1933719119828110
https://doi.org/10.1177/1933719119828110
Autor:
Greene Donald Royster, Harris, Justine C., Nelson, Amanda, Castro, Yessenia, R. Patrick Weitzel, Tisdale, John, Heitmann, Ryan J., DeCherney, Alan H., Wolff, Erin F.
Supplemental Material, TReg_and_Rapamycin_Supplemental_Table_2 for Rapamycin Corrects T Regulatory Cell Depletion and Improves Embryo Implantation and Live Birth Rates in a Murine Model by Greene Donald Royster, Justine C. Harris, Amanda Nelson, Yess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6033df26b8906f88a7af72051f6ed69
Autor:
Akihiro Yachie, Wade H. Ollivierre, Michael Eckhaus, R. Patrick Weitzel, Gennadiy Kovtunovych, Manik C. Ghosh, John F. Tisdale, Tracey A. Rouault
Publikováno v:
Blood. 124:1522-1530
Loss-of-function mutation in the heme oxygenase 1 (Hmox1) gene causes a rare and lethal disease in children, characterized by severe anemia and intravascular hemolysis, with damage to endothelia and kidneys. Previously, we found that macrophages enga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::248910b2aa2e3f54ff3bdb840fa504d3
https://doi.org/10.1182/blood-2014-02-554162
https://doi.org/10.1182/blood-2014-02-554162
Autor:
John F. Tisdale, Ryan J. Heitmann, Erin F. Wolff, James H. Segars, Yanling Feng, R. Patrick Weitzel
Publikováno v:
Reproductive sciences (Thousand Oaks, Calif.). 24(7)
Maternal immune tolerance of fetal engraftment is critical for the establishment and maintenance of pregnancy, but the exact mechanisms permitting this semi-allograft in the maternal host are not completely understood. Further, failure of the embryo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f1ae399bd76fa4ae96fb8960fb0811
https://pubmed.ncbi.nlm.nih.gov/27834288
https://pubmed.ncbi.nlm.nih.gov/27834288
Autor:
Aylin C. Bonifacino, R. Patrick Weitzel, Lydia N. Raines, Luke P Skala, Naoya Uchida, Anna Shvygin, Robert E. Donahue, John F. Tisdale, Allen E. Krouse, Mark E. Metzger
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Reduced intensity conditioning (RIC) is desirable for hematopoietic stem cell (HSC) gene therapy applications. However, low gene marking was previously observed in gene therapy trials, suggesting that RIC might be insufficient for (i) opening niches
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb87c6d4fd679f4a214f240b36e74c47
https://pubmed.ncbi.nlm.nih.gov/27652288
https://pubmed.ncbi.nlm.nih.gov/27652288
Autor:
Silvia F. Hernandez, Bo R. Rueda, Solji Park, R. Patrick Weitzel, N. Vahidi, Erin F. Wolff, John F. Tisdale
Publikováno v:
Nature medicine. 21(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eee57b48558fb7482e00936c6189e65
https://pubmed.ncbi.nlm.nih.gov/26444636
https://pubmed.ncbi.nlm.nih.gov/26444636
Autor:
John F. Tisdale, Wynona Coles, R. Patrick Weitzel, Jonathan D. Powell, Matthew M. Hsieh, Mary E. Link, Xiongce Zhao, Griffin P. Rodgers, Courtney D. Fitzhugh
Publikováno v:
JAMA. 312(1)
Importance Myeloablative allogeneic hematopoietic stem cell transplantation (HSCT) is curative for children with severe sickle cell disease, but toxicity may be prohibitive for adults. Nonmyeloablative transplantation has been attempted with degrees
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab80fc8d052bd3db2a937186363d5593
https://pubmed.ncbi.nlm.nih.gov/25058214
https://pubmed.ncbi.nlm.nih.gov/25058214
Autor:
Josiah Ballantine, Naoya Uchida, R. Patrick Weitzel, Robert E. Donahue, John F. Tisdale, Aylin C. Bonifacino, Sandra D. Price, Charlotte Platner, Allen E. Krouse, Mark E. Metzger
Publikováno v:
Molecular Therapy. 23:S118-S119
Reduced intensity conditioning (RIC) regimens are desirable for hematopoietic stem cell (HSC)-targeted gene therapy. However, in previous gene therapy trials, low gene marking was reported in peripheral blood cells, raising the question that RIC migh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e87d2c57f93ef6bb94825be8b514478e
Autor:
Wynona Coles, John F. Tisdale, Vincent Hathaway, Courtney D. Fitzhugh, Hayato Unno, Xiongce Zhao, Mary E. Link, Elizabeth C. Wright, David F. Stroncek, Gregory J. Kato, Matthew M. Hsieh, R. Patrick Weitzel
Peripheral blood stem cell (PBSC) infusions are associated with complications such as elevated blood pressure and decreased creatinine clearance. Patients with sickle cell disease experience similar manifestations, and some have postulated release of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb1cc4854d84db07e29c416a0e39614
https://europepmc.org/articles/PMC3382927/
https://europepmc.org/articles/PMC3382927/