Zobrazeno 1 - 10
of 98
pro vyhledávání: '"R P Schleimer"'
Autor:
L A Beck, S Dalke, K M Leiferman, C A Bickel, R Hamilton, H Rosen, B S Bochner, R P Schleimer
Publikováno v:
The Journal of Immunology. 159:2962-2972
RANTES, a member of the C-C chemokine family, is a potent chemoattractant for T lymphocytes and eosinophils, but not neutrophils. To determine the effect of RANTES on cell recruitment in vivo, we injected up to 4 microg of RANTES intradermally into b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3db60b1e9f136bcb9da31428f9145cc
https://doi.org/10.4049/jimmunol.159.6.2962
https://doi.org/10.4049/jimmunol.159.6.2962
Autor:
L M, Schwiebert, L A, Beck, C, Stellato, C A, Bickel, B S, Bochner, R P, Schleimer, L A, Schwiebert
Publikováno v:
Journal of Allergy and Clinical Immunology. 97:143-152
Summary We believe that there are the following four classes of glucocorticoid-sensitive cytokines that are involved in cell recruitment: (1) those that activate endothelium nonspecifically; (2) those that activate endothelium specifically; (3) those
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed187fc8965edcafd169a94e3420572
https://doi.org/10.1016/s0091-6749(96)80214-4
https://doi.org/10.1016/s0091-6749(96)80214-4
Publikováno v:
The Journal of Immunology. 154:799-803
Previous studies with human umbilical vein endothelial cells (HUVEC) have shown that the cytokine IL-4 induces adherence of human eosinophils, but not neutrophils, because of its ability to selectively induce surface expression of vascular cell adhes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ba45b48389051b9cdaa2aac1bcb25c1
https://doi.org/10.4049/jimmunol.154.2.799
https://doi.org/10.4049/jimmunol.154.2.799
Publikováno v:
The Journal of Immunology. 152:4590-4596
Activation of HUVEC monolayers by IL-1 beta or TNF-alpha induces migration of eosinophils across the endothelial monolayer (i.e., transendothelial migration) in vitro. In the present study, we demonstrate that culture of freshly isolated eosinophils
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::577fe1b5986479a087edb76935620843
https://doi.org/10.4049/jimmunol.152.9.4590
https://doi.org/10.4049/jimmunol.152.9.4590
Autor:
A, Keswani, R T, Chustz, L, Suh, R, Carter, A T, Peters, B K, Tan, R, Chandra, S-H, Kim, T, Azam, C A, Dinarello, R C, Kern, R P, Schleimer, A, Kato
Publikováno v:
Allergy. 67(1)
Chronic rhinosinusitis (CRS) is a heterogeneous disease characterized by local inflammation of the upper airways and sinuses and is frequently divided into polypoid CRS (CRSwNP) and nonpolypoid CRS (CRSsNP). However, the mechanism of inflammation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f75cf8519fe650eac39d0ac0e99e0d9
https://pubmed.ncbi.nlm.nih.gov/21899560
https://pubmed.ncbi.nlm.nih.gov/21899560
Publikováno v:
The Journal of Immunology. 151:4989-4997
Evidence is accumulating that suggests that granulocyte macrophage CSF (GM-CSF) may have inflammatory actions in addition to its effects as a hematopoietic growth factor. In these studies, the effects of culture of purified human eosinophils with GM-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be89dd29919ff7d287840f3eb056516c
https://doi.org/10.4049/jimmunol.151.9.4989
https://doi.org/10.4049/jimmunol.151.9.4989
Publikováno v:
The Journal of Immunology. 150:1084-1092
The cytokines IL-3 and granulocyte-macrophage CSF (GM-CSF) activate and/or prime monocytes, basophils, and eosinophils for a number of proinflammatory events in vitro. It was hypothesized that IL-3 and GM-CSF might also participate in the local infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15f329f00dedd584ee9850ce4630c034
https://doi.org/10.4049/jimmunol.150.3.1084
https://doi.org/10.4049/jimmunol.150.3.1084
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 40(4)
Discussions of eosinophils are often descriptions of end-stage effector cells with destructive capabilities mediated predominantly by released cytotoxic cationic granule proteins. Moreover, eosinophils in the medical literature are invariably associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ec4a878768d918c33c815cb3ae85a5b
https://pubmed.ncbi.nlm.nih.gov/20447076
https://pubmed.ncbi.nlm.nih.gov/20447076
Publikováno v:
The Journal of Immunology. 149:4021-4028
IL-1 beta promotes adhesiveness in human umbilical vein endothelial cells (HuVEC) for eosinophils through expression of adhesion molecules including intercellular adhesion molecules-1 (ICAM-1), E-selectin, and vascular cell adhesion molecule-1 (VCAM-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fe9757645d8331f71e7aa1efabf3692
https://doi.org/10.4049/jimmunol.149.12.4021
https://doi.org/10.4049/jimmunol.149.12.4021
Autor:
P T Peachell, B J Undem, R P Schleimer, D W MacGlashan, L M Lichtenstein, L B Cieslinski, T J Torphy
Publikováno v:
The Journal of Immunology. 148:2503-2510
We attempted to identify and establish the role of cyclic nucleotide phosphodiesterase (PDE) isozymes in human basophils by using standard biochemical techniques as well as describing the effects of isozyme-selective and nonselective inhibitors of PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::633ba8a89d8d16cfd324e1fff2f41a2e
https://doi.org/10.4049/jimmunol.148.8.2503
https://doi.org/10.4049/jimmunol.148.8.2503