Zobrazeno 1 - 10
of 55
pro vyhledávání: '"R P Phipps"'
Autor:
P. J. Simpson-Haidaris, S. J. Pollock, S. Ramon, N. Guo, C. F. Woeller, S. E. Feldon, R. P. Phipps
Publikováno v:
PPAR Research, Vol 2010 (2010)
The use of targeted cancer therapies in combination with conventional chemotherapeutic agents and/or radiation treatment has increased overall survival of cancer patients. However, longer survival is accompanied by increased incidence of comorbiditie
Externí odkaz:
https://doaj.org/article/06563ff9dd2c427bb6d386cbda16f3d0
Autor:
M. B. Taubman, C. W. Francis, N. Blumberg, D. L. Springer, G. M. Lehmann, S. Bancos, J. J. O'Brien, S. L. Spinelli, R. P. Phipps
Publikováno v:
PPAR Research, Vol 2008 (2008)
Externí odkaz:
https://doaj.org/article/8cf0d99671be4d4fb2b94c7c3bb82acb
Publikováno v:
The Journal of Immunology. 158:4670-4677
CD40 is an important signaling and activation Ag found on certain bone marrow-derived cells. Recently, CD40 also has been shown to be expressed by mesenchymal cells, including human fibroblasts. Little is known about the role of CD40 in fibroblasts.
Autor:
D M Brown, R P Phipps
Publikováno v:
The Journal of Immunology. 157:1359-1370
Apoptosis is a critical mechanism in the maturation and maintenance of the immune system. However, the process by which cells die remains poorly understood. The proto-oncogene bcl-2 is considered important in determining whether cells enter an apopto
Autor:
M A Borrello, R P Phipps
Publikováno v:
The Journal of Immunology. 155:4155-4161
B lymphocytes and macrophages are considered to be derived from separate lineages and to have specialized functions. However, some malignant B lymphocytes can generate descendants with macrophage-like properties and monocytoid B cells are described i
Publikováno v:
The Journal of Immunology. 154:162-170
The mechanism by which PG of the E series (PGE) promote murine B lymphocyte IgE production was investigated. We previously reported that PGE, and other agents that increase intracellular cAMP, synergize with IL-4 and LPS to induce IgE and IgG1 produc
Publikováno v:
The Journal of Immunology. 152:3606-3614
The purpose of this study was to determine whether or not membrane-bound and soluble forms of IL-4 receptors are expressed by isolated subsets of murine lung fibroblasts and to evaluate the potential functional consequences of IL-4 receptor triggerin
Autor:
R L Roper, R P Phipps
Publikováno v:
The Journal of Immunology. 149:2984-2991
Macrophage-secreted prostaglandins of the E series inhibit numerous immunologic events, including IgM secretion by B lymphocytes. In this study, we investigated whether PGE also regulates the activation of normal quiescent murine B cells and subseque
Autor:
S H Stein, R P Phipps
Publikováno v:
The Journal of Immunology. 148:3943-3949
IFN-gamma secretion by Th1 cells has been shown to preferentially promote the production of IgG2a in LPS-stimulated murine B lymphocytes. We recently reported that PGE2 potentiated the ability of IFN-gamma to augment IgG2a production in both Ag-speci
Autor:
S H Stein, R P Phipps
Publikováno v:
The Journal of Immunology. 147:2500-2506
Immune complexes (IC) can inhibit the differentiation of B lymphocytes into IgM secreting plasma cells in both Ag-specific and polyclonal systems. This report describes the ability of IC and IFN-gamma, or IFN-gamma and PGE2 to regulate the class of I