Zobrazeno 1 - 10
of 33
pro vyhledávání: '"R P Nordan"'
Autor:
James J. Mulé, David M. Jablons, R. P. Nordan, Joe K. McIntosh, Stuart Rudikoff, Steven A. Rosenberg, Michael T. Lotze
Publikováno v:
Annals of the New York Academy of Sciences. 557:572-575
Autor:
Michael T. Lotze, James J. Mulé, Stuart Rudikoff, David M. Jablons, R. P. Nordan, Joe K. McIntosh
Publikováno v:
Annals of the New York Academy of Sciences. 557:157-161
Publikováno v:
Journal of Clinical Investigation. 92:2152-2159
Neoplastic diseases are frequently associated with metabolic changes collectively known as cancer cachexia. The presence of cachexia complicates therapeutic intervention and is an important cause of death in cancer patients. At present there is no ef
Publikováno v:
The Journal of Immunology. 146:3462-3468
IL-6 and TNF-alpha are synthesized and secreted by normal tonsillar B cells after stimulation with the polyclonal B cell activator Staphylococcus aureus Cowan strain 1 (SAC) and IL-2 as well as spontaneously by in vivo activated B cells from patients
Publikováno v:
Blood. 77:587-593
It has been reported recently that freshly isolated human myeloma cell cultures proliferate in response to added interleukin-6 (IL-6). Endogenous levels of IL-6 found in the same cultures suggested that an autocrine growth loop may contribute to cell
Publikováno v:
Current protocols in immunology.
Interleukin 6 (IL-6) is a pluripotent cytokine with multiple effects on many different cell types. It is produced by a variety of cells in response to immunological and other stimuli. This unit describes a simple and sensitive assay for human, rat, r
Publikováno v:
Molecular and Cellular Biology. 10:2443-2447
IL6-PE40 is a chimeric toxin composed of human interleukin-6 (IL6) linked by a peptide bond to PE40, a form of Pseudomonas exotoxin (PE) devoid of its cell recognition domain. To identify cancer cell lines with high numbers of IL6 receptors and to as
Publikováno v:
Molecular and Cellular Biology. 10:2443-2447
IL6-PE40 is a chimeric toxin composed of human interleukin-6 (IL6) linked by a peptide bond to PE40, a form of Pseudomonas exotoxin (PE) devoid of its cell recognition domain. To identify cancer cell lines with high numbers of IL6 receptors and to as
Publikováno v:
Blood. 96(10)
Interleukin 6 (IL-6), the major growth factor for myeloma cells, signals through the activation of signal transducers and activators of transcription (STAT) proteins. An important step in the malignant progression of murine plasmacytomas is the trans
Publikováno v:
BioTechniques. 27(4)
Monocyte/macrophage cell lines are fastidious cells commonly used in transient transfection experiments. In the course of a study of gene regulation by lipopolysaccharide (LPS), we have compared several methods for DNA-mediated cell transfection to d