Zobrazeno 1 - 10
of 18
pro vyhledávání: '"R P Naoumova"'
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 10, Pp 2071-2078 (1997)
Apheresis only partially controls raised low density lipoprotein cholesterol levels in patients with homozygous familial hypercholesterolemia, who usually respond poorly to lipid-lowering drugs. The efficacy and mechanism of action of a new 3-hydroxy
Externí odkaz:
https://doaj.org/article/7b14782859364aa7bc9320dbb9e532ec
Autor:
R P Naoumova, S Dunn, L Rallidis, O Abu-Muhana, C Neuwirth, N B Rendell, G W Taylor, G R Thompson
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 7, Pp 1496-1500 (1997)
HMG-CoA reductase inhibitors or statins are effective in both the primary and secondary prevention of coronary heart disease, the extent of benefit being proportional to the reduction in low density lipoprotein (LDL) cholesterol achieved. Atorvastati
Externí odkaz:
https://doaj.org/article/9c33680c53c2432f91aed90ab9a08bb8
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 3, Pp 439-447 (1996)
The review examines the evidence that the supply of cholesterol available for incorporation into nascent lipoprotein particles exerts a regulatory influence on apolipoprotein (apo) B secretion by the liver. Support for this hypothesis comes both from
Externí odkaz:
https://doaj.org/article/9b44393d361a4495ad45b2f386938a75
Publikováno v:
Journal of Lipid Research, Vol 35, Iss 11, Pp 1946-1955 (1994)
To determine the acute and long-term effects of low density lipoprotein (LDL) reduction on cholesterol biosynthesis, we studied changes in the cholesterol precursors mevalonic acid (MVA) and lathosterol in patients with heterozygous familial hypercho
Externí odkaz:
https://doaj.org/article/5b61708483e046d3a4bf82aa6ae2a686
Autor:
M. A. Boroujerdi, Peter H. Sönksen, E Albany, A. M. Umpleby, M.H. Cummings, Peter J. Lumb, Anthony S. Wierzbicki, David Russell-Jones, Emanuel Christ, R. P. Naoumova
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 84:307-316
Patients with adult GH deficiency are often dyslipidemic and may have an increased risk of cardiovascular disease. The secretion and clearance of very low density lipoprotein apolipoprotein B 100 (VLDL apoB) are important determinants of plasma lipid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e83c6c88f1ee53af7c51b364a6f6a7c3
https://doi.org/10.1210/jcem.84.1.5365
https://doi.org/10.1210/jcem.84.1.5365
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 10, Pp 2071-2078 (1997)
The Journal of Lipid Research
2071-208
The Journal of Lipid Research
2071-208
Apheresis only partially controls raised low density lipoprotein cholesterol levels in patients with homozygous fa- milial hypercholesterolemia, who usually respond poorly to lipid-lowering drugs. The efficacy and mechanism of action of a new 3-hydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b89a3c1b788e836df27e23421e2f9a18
https://doi.org/10.1016/s0022-2275(20)37137-6
https://doi.org/10.1016/s0022-2275(20)37137-6
Autor:
Peter H. Sönksen, Gerald F. Watts, G.R. Thompson, Anne Umpleby, M.H. Cummings, R. P. Naoumova, B.M. Slavin
Publikováno v:
Metabolism. 44:1052-1057
The regulation of apolipoprotein B-100 (apo B) metabolism in man is not fully understood. In vitro studies suggest a key role for the hepatic availability of cholesterol substrate. We therefore examined whether there was a direct association between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4bf121fa1183a3ea532343b1a34ed70
https://doi.org/10.1016/0026-0495(95)90104-3
https://doi.org/10.1016/0026-0495(95)90104-3
Publikováno v:
European journal of clinical investigation. 33(1)
Statins have been shown to have pleiotropic effects extending beyond their ability to lower cholesterol.Seventeen patients with heterozygous familial hypercholesterolaemia participated in a single-blind placebo controlled study. The patients underwen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e2e43d71e24509536b4b64423de49edd
https://pubmed.ncbi.nlm.nih.gov/12492458
https://pubmed.ncbi.nlm.nih.gov/12492458
Publikováno v:
The Journal of clinical endocrinology and metabolism. 84(8)
We investigated the effect of reduction in visceral obesity on the kinetics of apolipoprotein B-100 (apoB) metabolism in a controlled dietary intervention study in 26 obese men. Hepatic secretion of very low density lipoprotein (VLDL) apoB was measur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::da09321a787ceb6fb623cc72dd76fa2c
https://pubmed.ncbi.nlm.nih.gov/10443691
https://pubmed.ncbi.nlm.nih.gov/10443691
Publikováno v:
European journal of clinical investigation. 29(5)
Atorvastatin is a potent inhibitor of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase, but its effect on bile acid synthesis is unknown. The objectives of the study were to determine the effect of atorvastatin on bile acid synthesis in patients in w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5fb41a0e132f05556dc84816589431cc
https://pubmed.ncbi.nlm.nih.gov/10354197
https://pubmed.ncbi.nlm.nih.gov/10354197