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Akademický článek

Cellular events of acute, resolving or progressive COVID-19 in SARS-CoV-2 infected non-human primates

Autor: M. D. Fahlberg, R. V. Blair, L. A. Doyle-Meyers, C. C. Midkiff, G. Zenere, K. E. Russell-Lodrigue, C. J. Monjure, E. H. Haupt, T. P. Penney, G. Lehmicke, B. M. Threeton, N. Golden, P. K. Datta, C. J. Roy, R. P. Bohm, N. J. Maness, T. Fischer, J. Rappaport, M. Vaccari

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)

Here, Fahlberg et al. describe the cellular immune response during acute, resolving or progressive COVID-19 in SARS-CoV-2 infected non-human primates. The study identifies associations of monocytes and macrophage subtypes in lungs with disease outcom

Externí odkaz: https://doaj.org/article/ed379c7b9e49434d81343f5e0569e2da

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Cross-protective immune responses induced in rhesus macaques by immunization with attenuated macrophage-tropic simian immunodeficiency virus

Autor: B Jagerski, D A Hauer, L N Martin, Janice E. Clements, R P Bohm, Stephanie A. Miller, A M Amedee, M C Zink, A M Trichel, Ronald C. Montelaro

Publikováno v: Journal of Virology. 69:2737-2744

The simian immunodeficiency virus (SIV) macaque model of AIDS has provided a valuable system with which to investigate vaccine approaches for protection against human immunodeficiency virus type 1 (HIV-1) infection. In particular, the ability of maca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd9f44a90663bf3dce68ec18e5327fa
https://doi.org/10.1128/jvi.69.5.2737-2744.1995

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Early and early disseminated phases of Lyme disease in the rhesus monkey: a model for infection in humans

Autor: M T, Philipp, M K, Aydintug, R P, Bohm, F B, Cogswell, V A, Dennis, H N, Lanners, R C, Lowrie, E D, Roberts, M D, Conway, M, Karaçorlu, G A, Peyman, D J, Gubler, B J, Johnson, J, Piesman, Y, Gu

Publikováno v: Infection and Immunity. 61:3047-3059

We demonstrate that Borrelia burgdorferi infection in the rhesus monkey mimics the early and early disseminated phases of human Lyme disease. Clinical, bacteriological, immunological, and pathological signs of infection were investigated during 13 we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5753a737838a5500168adc566911a9cd
https://doi.org/10.1128/iai.61.7.3047-3059.1993

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Anti-leprosy protective vaccination of rhesus monkeys with BCG or BCG plus heat-killed Mycobacterium leprae: lepromin skin test results

Autor: B J, Gormus, G B, Baskin, K, Xu, M S, Ratterree, P A, Mack, R P, Bohm, W M, Meyers, G P, Walsh

Publikováno v: Leprosy review. 73(3)

Groups of rhesus monkeys (RM) were vaccinated and boosted with living Mycobacterium bovis Bacillus Calmette-Guerin (BCG) or BCG + low dose (LD) heat-killed Mycobacterium leprae (HKML) or high dose (HD) HKML or were unvaccinated. Animals vaccinated wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e98a45b5ccd436b8a5340dc8eb08d0cc
https://pubmed.ncbi.nlm.nih.gov/12449891

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A method of video-assisted thoracoscopic surgery for collection of thymic biopsies in rhesus monkeys (Macaca mulatta)

Autor: R P, Bohm, R A, Rockar, M S, Ratterree, J L, Blanchard, J, Harouse, A, Gettie, C, Cheng-Mayer

Publikováno v: Contemporary topics in laboratory animal science. 39(6)

To support an infectious disease study, we developed a surgical procedure to collect serial thymic biopsies in rhesus monkeys (Macaca mulatta). In many instances in which thymic tissue is required from living animals, open surgical approaches (thorac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::23617007b551ff7f19f6f6c8fa4eedd6
https://pubmed.ncbi.nlm.nih.gov/11487248

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Antileprosy protective vaccination of sooty mangabey monkeys with BCG or BCG plus heat-killed Mycobacterium leprae: immunologic observations

Autor: B J, Gormus, G B, Baskin, K, Xu, M S, Ratterree, L N, Martin, P A, Mack, R P, Bohm, W M, Meyers, G P, Walsh

Publikováno v: International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 68(4)

Groups of sooty mangabey monkeys (SMM) were vaccinated and boosted with Mycobacterium bovis bacillus Calmette-Guerin (BCG), or BCG + low-dose (LD) or high-dose (HD) heat-killed M. leprae (HKML), or were unvaccinated. Prior to and following vaccinatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::76e8f50fe3f9dbbedcd069f60bea5905
https://pubmed.ncbi.nlm.nih.gov/11332286

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Identification of SIV env-specific CTL in the jejunal mucosa in vaginally exposed, seronegative rhesus macaques (Macaca mulatta)

Autor: L A, Wilson, M, Murphey-Corb, L N, Martin, R M, Harrison, M S, Ratterree, R P, Bohm

Publikováno v: Journal of medical primatology. 29(3-4)

We previously reported major histocompatibility complex Class I-restricted cytotoxic T lymphocytes (CTL) in jejunal lamina propria (LP) of monkeys following colonic exposure to subinfectious SIV doses. Those monkeys with strong mucosal CTL responses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e1d67e9e7472c6aa022a02eb7930889d
https://pubmed.ncbi.nlm.nih.gov/11085580

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Antileprosy protective vaccination of rhesus monkeys with BCG or BCG plus heat-killed Mycobacterium leprae: immunologic observations

Autor: B J, Gormus, G B, Baskin, K, Xu, M S, Ratterree, L N, Martin, P A, Mack, R P, Bohm, W M, Meyers, G P, Walsh

Publikováno v: International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 68(1)

Groups of rhesus monkeys were vaccinated and boosted with Mycobacterium bovis bacillus Calmette Guerin (BCG) or BCG plus low-dose (LD) or high-dose (HD) heat-killed M. leprae (HKML), or were unvaccinated. Prior to and following vaccination-boosting a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8aa8bcd1c974744fb66d827cc8351957
https://pubmed.ncbi.nlm.nih.gov/10834067

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Ethanol suppression of the functional state of polymorphonuclear leukocytes obtained from uninfected and simian immunodeficiency virus infected rhesus macaques

Autor: D A, Stoltz, P, Zhang, S, Nelson, R P, Bohm, M, Murphey-Corb, G J, Bagby

Publikováno v: Alcoholism, clinical and experimental research. 23(5)

Human immunodeficiency virus (HIV) infection and alcohol abuse frequently coexist in the host and are known to suppress individually the host response to a variety of opportunistic infections.This study examined the effects of in vitro ethanol exposu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0d9b3d2aa9bb1630fa6fb975f9b53b49
https://pubmed.ncbi.nlm.nih.gov/10371409

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Chronic lyme disease in the rhesus monkey

Autor: E D, Roberts, R P, Bohm, F B, Cogswell, H N, Lanners, R C, Lowrie, L, Povinelli, J, Piesman, M T, Philipp

Publikováno v: Laboratory investigation; a journal of technical methods and pathology. 72(2)

We have previously reported the clinical, pathologic, and immunologic features of "early" Borrelia burgdorferi infection in rhesus monkeys (3). We have now evaluated these features during the chronic phase of Lyme disease in this animal model.Clinica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::34d0d44ee59a40959d7e59919d589c3d
https://pubmed.ncbi.nlm.nih.gov/7853847

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