Zobrazeno 1 - 10
of 55
pro vyhledávání: '"R P, Rubin"'
Autor:
J. B. Adams, M. Baral, E. Geis, J. Mitchell, J. Ingram, A. Hensley, I. Zappia, S. Newmark, E. Gehn, R. A. Rubin, K. Mitchell, J. Bradstreet, J. M. El-Dahr
Publikováno v:
Journal of Toxicology, Vol 2009 (2009)
This study investigated the relationship of children's autism symptoms with their toxic metal body burden and red blood cell (RBC) glutathione levels. In children ages 3–8 years, the severity of autism was assessed using four tools: ADOS, PDD-BI, A
Externí odkaz:
https://doaj.org/article/fe0dc4e4de1348b2bf6a4a6f3705379f
Publikováno v:
Agents and Actions. 31:237-242
Nedocromil sodium (10(-10) - 10(-9) M) produced a dose-related inhibition of superoxide anion generation induced by platelet activating factor (PAF) in human polymorphonuclear leukocytes (PMNs). At a higher concentration (3 x 10(-7) M), nedocromil so
Publikováno v:
The Biochemical journal. 340
The present study examines the cellular distribution of the ryanodine receptor/channel (RyR) and inositol 1,4,5-trisphosphate receptor (InsP3R) subtypes in parotid acini. Using fluorescently labelled 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-3-propi
Publikováno v:
Biochemical pharmacology. 52(4)
We investigated the expression, distribution, and activation parameters of protein kinase C (PKC) isozymes in isolated rat parotid acinar cells. By analyzing cellular extracts by western blot analysis and for isozyme-specific RNA, the Ca(2+)-independ
Autor:
R P, Rubin, M A, Adolf
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 268(2)
This study examined the mechanistic basis of the synergistic interaction between the cyclic AMP (cAMP) and phosphoinositide pathways in salivary amylase secretion. cAMP produced a concentration-dependent increase in Ca++ mobilization from saponin-per
Publikováno v:
Molecular pharmacology. 43(2)
Previous data showed that carbachol (CCh) elicits a concentration-dependent increase in phosphatidylinositol (PtdIns) 4-kinase activity in homogenates derived from agonist-stimulated pancreatic acini. In the present study CCh elicited a time-dependen
Autor:
M P Schrey, R P Rubin
Publikováno v:
Journal of Biological Chemistry. 254:11234-11241
Publikováno v:
Biochemical Journal. 233:929-932
Accumulating evidence suggests that the increase in cytosolic Ca2+ induced by receptor agonists is mediated by inositol 1,4,5-trisphosphate, a product of phospholipase C-mediated breakdown of phosphatidylinositol 4,5-bisphosphate. The present study e
Publikováno v:
The Journal of Physiology. 274:367-379
1. The effects of noradrenaline on the secretion of renin and on the efflux of Ca have been investigated in the isolated cat kidney perfused with Locke solution containing the alpha-adrenergic blocking agent, phenoxybenzamine, to block increases in r
Publikováno v:
Biochemical Journal. 219:655-659
The formation of inositol phosphates in response to secretagogues was studied in rat pancreatic acini preincubated with [3H]inositol. Carbachol caused rapid increases in radioactive inositol phosphate, inositol bisphosphate and inositol trisphosphate