Zobrazeno 1 - 10
of 38
pro vyhledávání: '"R P, Kinkel"'
Autor:
Ellen M Mowry, Robert F Carey, Maria R Blasco, Jean Pelletier, Pierre Duquette, Pablo Villoslada, Irina Malikova, Elaine Roger, R Phillip Kinkel, Jamie McDonald, Peter Bacchetti, Emmanuelle Waubant
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75416 (2013)
OBJECTIVE: Patients with early multiple sclerosis (MS) have stereotyped attack severity and recovery. We sought to determine if polymorphisms in MS susceptibility genes are associated with these attack features or with the risk of a second attack. ME
Externí odkaz:
https://doaj.org/article/b4e725b3cd45433f9efe6d01618c7c98
Autor:
Ellen M Mowry, Robert F Carey, Maria R Blasco, Jean Pelletier, Pierre Duquette, Pablo Villoslada, Irina Malikova, Elaine Roger, R Phillip Kinkel, Jamie McDonald, Peter Bacchetti, Emmanuelle Waubant
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75565 (2013)
OBJECTIVE: The anatomic location of subsequent relapses in early multiple sclerosis (MS) appears to be predicted by the first attack location. We sought to determine if genetic polymorphisms associated with MS susceptibility are associated with attac
Externí odkaz:
https://doaj.org/article/57f8bcbe73e143ea9bb7cd94e0009e5a
Autor:
D. Barlett, L. Vining, J. Friedman, F. Munschauer, T. Anderson, J. Wolinsky, J. Lynn, G. Liu, R. Arnoutelis, T. Bental, J. Rose, David I. Kaufman, J. Astruc, E. Cerretta, M. Petrie, A. Goodman, R. P. Kinkel, J. Herbert, M. Kaufman, D. Snider, J. Guarnaccia, M. Freedman, D. Pfohl, K. Costello, P. Mandalfind, E. Eggenberger, D. Court, D. Stefoski, J. McGee, L. Cappolino, R. Dubois, C. Bever, W. Morrison, S. Galetta, G. Rice, T. Grabowski, D. Patry, H. Rabinowicz, J. Richert, C. Tornatore, E. Carter, J. Kline, S. Putnam, R. Lesser, L. Scheller, E. Holzemer, J. Cohen, L. Pappert, C. Miller, Michael Wall, C. Smith, K. Rammohan, J. Burns, L. M. Metz, W. Stuart, M. Reiss, P. O'Connor, A. Blumenfeld, T. Gray, S. Hamilton, L. Durcan, W. Fenton, D. Arnold, L. Rolak, T. Murray, J. Selhourst, D. Stuart, G. Bernier, David L. Jacobson, A. Wallin, A. Stiffort, J. Rosenberg, L. Jacobs, J. Brillman, J. Oger, M. Kupersmith, David Mattson, F. Bhan, J. Goldstein, B. Apatoff, K. Karlin, J. O'Bannon, U. Webb, G. Glista, K. Arapello, S. Hashimoto, D. Bolibrush, S. Thurston, T. Scott, H. Panitch, P. Duquette, D. McHugh, A. Davis, M. Butler, Jack H. Simon, P. Fleming, D. Kuder, P. Weldon, Staley A. Brod
Publikováno v:
Multiple Sclerosis. 8:330-338
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9da2c92d9cd9352111fe0a0ff96d008
https://doi.org/10.1191/1352458502ms819oa
https://doi.org/10.1191/1352458502ms819oa
Autor:
N. A. Simonian, J H Simon, Roy W. Beck, T J Murray, Lawrence Jacobs, Alfred Sandrock, P J Slasor, C. M. Brownscheidle, R. P. Kinkel
Publikováno v:
New England Journal of Medicine. 343:898-904
Background Treatment with interferon beta has been shown to help patients with established multiple sclerosis, but it is not known whether initiating treatment at the time of a first clinical demyelinating event is of value. Methods We conducted a ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2fe5afbffdc39a928d63a61a89c20be
https://doi.org/10.1056/nejm200009283431301
https://doi.org/10.1056/nejm200009283431301
Autor:
N. A. Simonian, Kathy O'Reilly, J. S. Fischer, Michele K. Mass, Jonathan Braiman, Lawrence Jacobs, K. E. Wende, Frederick E. Munchsauer, Barbara J. Scherokman, Carol M. Brownscheidle, Carl V. Granger, Robert M. Herndon, David S. Dougherty, David M. Bartoszak, Donald E. Goodkin, John R. Richert, Bianca Weinstock-Guttman, Richard A. Rudick, Roger L. Priore, Andres M. Salazar, Diane Cookfair, Stanley L. Cohan, Ruth H. Whitham, Dennis Bourdette, Michael E. Coats, R. P. Kinkel, Richard M. Ransohoff, Patrick M. Pullicino, Jack H. Simon
Publikováno v:
Journal of Neuroimmunology. 93:8-14
Background and objective : This report provides results of CSF analyses done in a subset of relapsing remitting MS patients participating in a placebo-controlled, double-blind, phase III clinical trial of IFNβ-Studies supported by the National Multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::694ae9218bef5793925f24d4e27180ff
https://doi.org/10.1016/s0165-5728(98)00174-x
https://doi.org/10.1016/s0165-5728(98)00174-x
Autor:
Bianca Weinstock-Guttman, M. M. Uccelli, D. Gogol, J. E. Perryman, L. Neilley, R. P. Kinkel, M. Secic, S. VanderBrug Medendorp, Donald E. Goodkin
Publikováno v:
Neurology. 51:239-245
Objective: To compare the tolerability and efficacy of two doses of IV methylprednisolone in patients with secondary-progressive MS. Methods: IV methylprednisolone administered in high or low dose every other month for up to 2 years to 108 patients w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a00a41f6980208fe58b1bbb4f6fb633
https://doi.org/10.1212/wnl.51.1.239
https://doi.org/10.1212/wnl.51.1.239
Autor:
Frederick Munschauer, J. S. Fischer, Michele Mass, Diane Cookfair, John R. Richert, Ruth H. Whitham, Dennis Bourdette, Michael E. Coats, M. Campion, Barbara J. Scherokman, Carol M. Brownscheidle, Carl V. Granger, R. P. Kinkel, Donald E. Goodkin, Robert M. Herndon, Roger L. Priore, Lawrence Jacobs, Bianca Weinstock-Guttman, John J. Alam, RA Rudick, David S. Dougherty, Stanley Cohan, Andres M. Salazar, K. E. Wende, David M. Bartoszak, Patrick M. Pullicino, Jack H. Simon, J. Braiman
Publikováno v:
Multiple Sclerosis. 4:480-486
We compared the ability of the Kurtzke Expanded Disability Status Scale (EDSS) and a composite outcome of non-physician-based measures of time to ambulate 25 feet (TA) and manual dexterity (the Box and Block Test [BBT], and 9-Hole Peg Test [9HPT]) to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2920bfba3e37e14060f1964b94d64338
https://doi.org/10.1191/135245898678845179
https://doi.org/10.1191/135245898678845179
Autor:
Ann Scherzinger, Bianca Weinstock-Guttman, Frederick Munschauer, Carol M. Brownscheidle, Carl V. Granger, Roger L. Priore, Richard A. Rudick, John J. Alam, Patrick M. Pullicino, Lawrence Jacobs, Jack H. Simon, Robert M. Herndon, Michele Mass, Andres M. Salazar, Jeanelle Sheeder, K. E. Wende, N. A. Simonian, Stanley Cohan, Michelle Lajaunie, David S. Dougherty, Jonathan Braiman, Diane Cookfair, J. S. Fischer, Ruth H. Whitham, Michael E. Coats, Mary Joel Meyer, Donald E. Goodkin, David M. Bartoszak, Kim Choi, Dennis Bourdette, Barbara J. Scherokman, John R. Richert, R. P. Kinkel, Anna L. Martens-Davidson, M. Campion
Publikováno v:
Annals of Neurology. 43:79-87
The Multiple Sclerosis Collaborative Research Group trial was a double-blind, randomized, multicenter, phase III, placebo-controlled study of interferon beta-1a (IFNbeta-1a; AVONEX) in relapsing forms of multiple sclerosis. Initial magnetic resonance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0e5eab1a6185ca6b61e8aaa1f979845
https://doi.org/10.1002/ana.410430114
https://doi.org/10.1002/ana.410430114
Autor:
Frederick Munschauer, R. P. Kinkel
Publikováno v:
Clinical Therapeutics. 19:883-893
In separate clinical trials, two preparations of recombinant interferon (IFN)-beta, IFN beta-1a and IFN beta-1b, reduced exacerbation rates in relapsing-remitting multiple sclerosis (RR-MS). Further, IFN beta-1a slows the progression of disability in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::914396101a98a68dc0cbb6b386e24a1f
https://doi.org/10.1016/s0149-2918(97)80042-2
https://doi.org/10.1016/s0149-2918(97)80042-2
Autor:
R. H. Whitham, D. S. Dougherty, P. M. Pullicino, David M. Bartoszak, Michael E. Coats, J. S. Fischer, Jack H. Simon, C. M. Brownscheidle, L. D. Jacobs, Richard A. Rudick, B. Weistock-Guttman, N. A. Simonian, B. J. Scherokman, J. R. Richert, C. V. Granger, Robert M. Herndon, Michele Mass, D. L. Cookfair, Andres M. Salazar, R. L. Priore, J. J. Alam, R. P. Kinkel, Dennis Bourdette, F. E. Munschauer, Jonathan Braiman, S. L. Cohan, Donald E. Goodkin, M. K. Campion
Publikováno v:
Neurology. 49:358-363
Background and Objective: A phase III double-blind, placebo-controlled clinical trial demonstrated that interferon beta-la (IFNβ-1a) (Avonex, Biogen) significantly delayed progression of disability in relapsing MS patients. The primary clinical outc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e29bb515d0eef4fe10f80d9ae4105c35
https://doi.org/10.1212/wnl.49.2.358
https://doi.org/10.1212/wnl.49.2.358