Zobrazeno 1 - 10
of 14
pro vyhledávání: '"R P, Artymyshyn"'
Publikováno v:
Journal of Biological Chemistry. 269:31850-31857
Exposure of P11 cells to serotonin (5-HT) resulted in a transient increase in levels of 5-HT2A receptor mRNA. Exposure to 5-HT for as short a time as 1 min was sufficient to trigger a delayed increase in receptor mRNA. 5-HT-induced increases in recep
Publikováno v:
The Anatomical Record. 231:548-558
Dopamine D2 receptor mRNAs have recently been cloned and their gross distribution in the central nervous system described. Quantitative in situ hybridization histochemistry with a cRNA probe complementary to the mRNAs encoding approximately 70% of th
Publikováno v:
Journal of Neuroscience Methods. 32:185-192
To avoid repeated production of 125I tissue mash standards and to decrease inter-experiment variability, a set of commercially available, high activity plastic 3H standards was calibrated for use with 125I autoradiographs. Standards with a range of 2
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 295(3)
The regional distribution and cellular localization of dopamine D3 receptors in the rat brain was examined using quantitative autoradiography. [(125)I]7-OH-PIPAT bound in a saturable and reversible manner and exhibited subnanomolar affinity for a sin
Publikováno v:
Brain research. Molecular brain research. 39(1-2)
In this study, the relationship between the expression of 5-HT 2A receptors and level of 5-HT 2A receptor mRNA in discrete regions of rat brain was examined by inactivating 5-HT 2A receptors with the alkylating agent N -ethoxycarbonyl-2-ethoxy-1,2-di
Publikováno v:
The Journal of biological chemistry. 269(50)
Exposure of P11 cells to serotonin (5-HT) resulted in a transient increase in levels of 5-HT2A receptor mRNA. Exposure to 5-HT for as short a time as 1 min was sufficient to trigger a delayed increase in receptor mRNA. 5-HT-induced increases in recep
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 271(3)
Mechanisms underlying agonist- and antagonist-induced up-regulation in HEK-293 cells transfected to express D2 dopamine receptors were investigated. We have reported previously that exposure of cells to agonists and antagonists led to an increase in
Publikováno v:
Molecular pharmacology. 44(2)
Selective expression of subtypes of receptors in mammalian cell lines permits the study of the regulation of receptors in a homogeneous population of cells growing under controlled conditions. cDNAs encoding the human D2L and D2S receptors were ligat
Publikováno v:
Molecular pharmacology. 43(5)
Multiple subtypes of dopamine receptors with similar properties have been described. Ligands that have been shown to interact with a single subtype of receptor do not yet exist. The use of immunologic methods provides an alternative approach to disti
Publikováno v:
Brain research. 584(1-2)
Three outbred (Sprague-Dawley, Wistar and Long-Evans) and five inbred (Brown-Norway, Buffalo, DA, Fisher and Lewis) strains of rat were used to investigate the extent of genetic variation in the expression and organization of the rat D2 receptor locu