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Akademický článek
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Publikováno v:
Biomechanics and Modeling in Mechanobiology. 21:55-77
The aortic valve is a highly dynamic structure characterized by a transvalvular flow that is unsteady, pulsatile, and characterized by episodes of forward and reverse flow patterns. Calcific aortic valve disease (CAVD) resulting in compromised valve
Akademický článek
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Autor:
Kourtney F Smith, Christopher P. Kabb, Sean R. Niemi, Brent S. Sumerlin, Yifan Zhang, Duane Mitchell, S. Tori Ellison, Mathew Sebastian, Catherine Flores, W. Gregory Sawyer, Kyle D. Schulze, David Tran, Thomas E. Angelini, Ginger Moore, Cameron Morley, Christopher S. O’Bryan, Tapomoy Bhattacharjee
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Nature Communications
Nature Communications
With improving biofabrication technology, 3D bioprinted constructs increasingly resemble real tissues. However, the fundamental principles describing how cell-generated forces within these constructs drive deformations, mechanical instabilities, and
Autor:
Curtis R. Taylor, Kyle D. Schulze, Sean R. Niemi, W. Gregory Sawyer, Kyle J. LeBlanc, Alexander I. Bennett, Thomas E. Angelini, Kathryn L. Harris
Publikováno v:
ACS biomaterials scienceengineering. 2(10)
Fluid instabilities limit the ability of features to hold their shape in many types of 3D printing as liquid inks solidify into written structures. By 3D printing directly into a continuum of jammed granular microgels, these instabilities are circumv
Autor:
Angela A. Pitenis, Sean R. Niemi, Eric O. McGhee, Morgan R. Jones, Kyle D. Schulze, Samuel M. Hart, Samantha L. Marshall, Juan Manuel Urueña
Publikováno v:
Tribology Transactions. 62:135-143
Past studies have shown that the inclusion of fillers in a polytetrafluoroethylene (PTFE) matrix can improve wear resistance by nearly four orders of magnitude. These discoveries have prompted seve...
Autor:
Jiho Kim, Samuel M. Hart, Sean R. Niemi, Samantha L. Marshall, Juan Manuel Urueña, Erik R. Reale, Thomas E. Angelini, Eric O. McGhee, W. Gregory Sawyer, Kyle D. Schulze, Angela A. Pitenis, Alexander I. Bennett, Alison C. Dunn
Publikováno v:
Tribology - Materials, Surfaces & Interfaces. 11:180-186
Despite the ubiquitous use of soft materials in everything from transportation to biomedicine, there remain tremendous opportunities for fundamental studies on the governing principles behind their...
Autor:
Thomas E. Angelini, Kyle D. Schulze, Juan Manuel Urueña, Samuel M. Hart, Tapomoy Bhattacharjee, W. Gregory Sawyer, Samantha L. Marshall, Tristan T. Hormel, Angela A. Pitenis, Sean R. Niemi
Publikováno v:
Biotribology. 11:77-83
The tear film is a thin, aqueous, mucin-rich layer on the ocular surface that provides hydration and lubrication for healthy vision. The ability of the tear film to provide a highly lubricious interface during ocular movement is largely attributed to
Autor:
Sidhika Balachandar, Curtis R. Taylor, Thomas E. Angelini, Christopher S. O’Bryan, Nicholas Baldwin, S. Tori Ellison, Tapomoy Bhattacharjee, W. Gregory Sawyer, Sean R. Niemi
Publikováno v:
MRS Bulletin. 42:571-577
Three-dimensional (3D) printing has expanded beyond the mere patterned deposition of melted solids, moving into areas requiring spatially structured soft matter—typically materials composed of polymers, colloids, surfactants, or living cells. The t
Autor:
Derek L. Hood, W. Gregory Sawyer, Kyle D. Schulze, Eric O. McGhee, Samuel M. Hart, Sean R. Niemi, Angela A. Pitenis, Juan Manuel Urueña, Padraic P. Levings
Publikováno v:
Tribology Letters. 66
Tribological evaluation of biological materials, such as cells and tissues, present both opportunities and challenges to experimentalists. When working with living materials, maintaining homeostasis during testing in vitro or in vivo often requires a