Výsledky vyhledávání

Autor: R N, Taub, M L, Keohan, J C, Chabot, K S, Fountain, M, Plitsas

Publikováno v: Current Treatment Options in Oncology. 1:303-312

Malignant peritoneal mesothelioma is an aggressive neoplasm that rapidly spreads within the confines of the abdominal cavity to involve most accessible peritoneal and omental surfaces. Current treatments are unsatisfactory, and new approaches are nee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a45f39d5b17a833040f3f601c9f155e4
https://doi.org/10.1007/s11864-000-0046-5

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Architectural organization in the interphase nucleus of the protozoan Trypanosoma brucei: location of telomeres and mini-chromosomes

Autor: C. Shea, R. N. Taub, L. H. T. Van Der Ploeg, Doris B. Tse, Hui-Min Chung, S. Fields

Publikováno v: The EMBO Journal. 9:2611-2619

We studied the spatial organization of chromatin in the interphase G1, S and G2 nucleus of the protozoan Trypanosoma brucei, applying in situ hybridization with conventional fluorescence and confocal scanning optical microscopy. The majority of the t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb989461990d0d02b27dd76ef6d3bbe
https://doi.org/10.1002/j.1460-2075.1990.tb07443.x

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Chemotherapy for malignant mesothelioma

Autor: R N, Taub, K H, Antman

Publikováno v: Seminars in thoracic and cardiovascular surgery. 9(4)

The treatment of malignant mesothelioma (MM) has been challenging. Many series from larger single institutions comprise small numbers of selected patients. Positive studies tend to be published, whereas publication of negative studies is delayed, app

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e388e8b9f5b3998d13668225567c0819
https://pubmed.ncbi.nlm.nih.gov/9352953

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Chemotherapy for advanced sarcoma: therapeutic decisions and modalities

Autor: M L, Keohan, R N, Taub

Publikováno v: Seminars in oncology. 24(5)

In patients who have advanced soft tissue sarcoma that is no longer localized, systemic chemotherapy is the most reasonable option for treatment. The decision to treat or to use experimental or conventional agents should be based on the clinical asse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::38a198a1aef0830d946f5f6297d5758f
https://pubmed.ncbi.nlm.nih.gov/9344324

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Homogeneously staining region in anthracycline-resistant HL-60/AR cells not associated with MDR1 amplification

Autor: J E, Gervasoni, R N, Taub, M T, Yu, D, Warburton, M, Sabbath, S, Gilleran, D L, Coppock, J, D'Alessandri, S, Krishna, M, Rosado

Publikováno v: Cancer research. 52(19)

Anthracycline-resistant HL-60/AR cells and their drug-sensitive HL-60/S counterparts were characterized by karyotypic analysis and examined for the overexpression of DNA and mRNA sequences coding for P-glycoprotein (Pgp). The HL-60/S cells were karyo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::78ef23654f14cceb64df82443bf0b1b0
https://pubmed.ncbi.nlm.nih.gov/1394128

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Subcellular distribution of daunorubicin in P-glycoprotein-positive and -negative drug-resistant cell lines using laser-assisted confocal microscopy

Autor: J E, Gervasoni, S Z, Fields, S, Krishna, M A, Baker, M, Rosado, K, Thuraisamy, A A, Hindenburg, R N, Taub

Publikováno v: Cancer research. 51(18)

Four well defined multidrug-resistant cell lines and their drug-sensitive counterparts were examined for intracellular distribution of daunorubicin (DNR) by laser-assisted confocal fluorescence microscopy: P-glycoprotein-negative HL-60/AR cells, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::774b74b72cbce69ecb8b039853fbe980
https://pubmed.ncbi.nlm.nih.gov/1680024

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Human leukemic myeloblasts and myeloblastoid cells contain the enzyme cytidine 5'-monophosphate-N-acetylneuraminic acid:Gal beta 1-3GalNAc alpha (2-3)-sialyltransferase

Autor: A, Kanani, D R, Sutherland, E, Fibach, K L, Matta, A, Hindenburg, I, Brockhausen, W, Kuhns, R N, Taub, D H, van den Eijnden, M A, Baker

Publikováno v: Cancer research. 50(16)

We have examined the role of CMP-NeuAc:Gal beta 1-3GalNAc-R alpha(2-3)-sialyltransferase in fresh leukemia cells and leukemia-derived cell lines. Enzyme activity in normal granulocytes using Gal beta 1-3GalNAc alpha-o-nitrophenyl as substrate was 1.5

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::edab920967e5f2d51ac285d0d4ba586b
https://pubmed.ncbi.nlm.nih.gov/2379165

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