Výsledky vyhledávání - "R N, Stepanenko"

Synthesis of a conjugate of 3´-sialyllactoside with recombinant flagellin as a carrier protein and assessment of its immunological activity in comparison with that of a similar hemocyanin-based conjugate

Autor: O. A. Zeynalov, Yu. E. Tsvetkov, D. A. Goncharuk, R. N. Stepanenko, E. M. Novikova, Nikolay E. Nifantiev, N. A. Razvalyaeva, Elena A. Khatuntseva

Publikováno v: Russian Chemical Bulletin. 64:1640-1647

In the framework of a project directed to the design of synthetic cancer vaccines based on carbohydrate chains of tumor-associated gangliosides, a new prototype cancer vaccine, a polyvalent carbohydrate-protein conjugate 1 with ∼11 3´-sialyllactos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dfb830a9629a42893a34d4d7d8a18c45
https://doi.org/10.1007/s11172-015-1054-8

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Antitumor effect of the conjugate of synthetic carbohydrate moiety of the tumor-associated ganglioside GM3 with hemocyanin in combination with the cytostatic cyclophosphamide

Autor: Elena A. Khatuntseva, O. V. Kozyreva, Nikolay E. Nifantiev, E. M. Novikova, Yu. E. Tsvetkov, R. N. Stepanenko

Publikováno v: Russian Chemical Bulletin. 63:1431-1437

Based on the carbohydrate chains of tumor-associated ganglioside, polyvalent carbohydrate-protein conjugate 1 was synthesized suitable as a prototype of a cancer vaccine containing ∼400 residues of 3′-(N-acetyl-a-neuraminyl)lactose (3′-sialylla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc96f0d6cb67473776c801d13dd8ecf7
https://doi.org/10.1007/s11172-014-0614-7

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Synthesis of 2-aminoethyl 3′-(N-glycolylneuraminyl)-β-actoside and neoglycoconjugates based thereon — a prototype of a cancer vaccine and artificial antigens for the control of immune response

Autor: R. V. Petrov, Elena A. Khatuntseva, R. N. Stepanenko, R. Ya. Vlasenko, Nikolay E. Nifantiev, Yu. E. Tsvetkov

Publikováno v: Russian Chemical Bulletin. 58:450-456

The 2-aminoethyl β-glycoside of the trisaccharide 3′-(N-glycolylneuraminyl)lactose was synthesized in the framework of studies of approaches to the preparation of synthetic tumor vaccines based on carbohydrate chains of tumor-associated gangliosid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c0a477a2f8889e551096b5856bf8352
https://doi.org/10.1007/s11172-010-0032-4

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Synthesis of 3-aminopropyl β-glycoside of sialyl-3′-lactose and derived neoglycoconjugates as a tumor vaccine prototype and artificial antigens for the control of immune response

Autor: Yu. E. Tsvetkov, V. L. Lvov, Alexey A. Grachev, R. N. Stepanenko, Olga N. Yudina, R. Ya. Vlasenko, Nikolay E. Nifantiev, Elena A. Khatuntseva

Publikováno v: Russian Chemical Bulletin. 55:2095-2102

Starting from the biotechnologically available trisaccharide sialyl-3′-lactose, representing the carbohydrate portion of the tumor-associated ganglioside GM3, the corresponding 3-aminopropyl β-glycoside (1) and 3-(4-maleimidobutanoylamino)propyl g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::64878d2038dcfd39364a2f05219e8fe2
https://doi.org/10.1007/s11172-006-0554-y

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A conjugate of an oligosaccharide fragment of tumor-associated ganglioside antigen with hemocyanin is a prototype antitumor vaccine

Autor: V. L. Lvov, Nikolay E. Nifant'ev, R. N. Stepanenko, R. Ya. Vlasenko, Elena A. Khatuntseva, Yu. E. Tsvetkov, R. V. Petrov

Publikováno v: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections. 415

Specific stimulation of the immune system against tumor antigens, which may result in elimination of malignant cells, may be performed with the use of vaccines containing a specific native or synthetic tumorassociated antigen. To develop a prototype

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b71cc53442af58f1994220e17fb4399
https://pubmed.ncbi.nlm.nih.gov/17929671

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Comparison of the proliferative and immunoglobulin-secreting ability of peripheral blood lymphocytes of healthy subjects and patients with B-cell immunoproliferative disease

Autor: A. E. Kopylov, L. V. Koval'chuk, R. N. Stepanenko, A. K. Golenkov, I. N. Nazarova

Publikováno v: Bulletin of Experimental Biology and Medicine. 112:1781-1783

The proliferative response and in vitro immunoglobulin production induced polyclonal activators were studied in 12 patients with multiple myeloma (MM) and in 15 healthy individuals. The spontaneous production of IgM was decreased. PWM-induced immunog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cd60ca44a6b07c2968139f612dd4abd9
https://doi.org/10.1007/bf00840523

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