Zobrazeno 1 - 10
of 23
pro vyhledávání: '"R N, Mishaeva"'
Publikováno v:
Russian Chemical Bulletin. 62:918-927
The review covers studies of the reactions of glutaraldehyde with dipolar ions of amino acids and proteins in neutral aqueous solutions. The formation of imines and the accompanying aldol condensation of glutaraldehyde are acid-catalyzed reactions.
Publikováno v:
Russian Chemical Bulletin. 62:6-19
Development of the scientific principles involved in the creation of soluble macromolecular modifications of the native protein, hemoglobin, is surveyed. The main goal of the research is practical application of the results to develop blood substitut
Autor:
E. F. Panarin, L. R. Gudkin, N. P. Kuznetsova, R. N. Mishaeva, T. E. Sukhanova, E. A. Berezetskaya, M. E. Vylegzhanina
Publikováno v:
Scopus-Elsevier
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The process of association-dissociation of hemoglobin molecules into dimers of its subunits in water and water-saline solutions is studied by the method of gel-penetrating chromatography and ultrafiltration. The quantitative assessment of stabilizati
Publikováno v:
Russian Journal of Applied Chemistry. 80:1598-1603
A procedure was developed for purification of concentrated hemoglobin solutions from hemolyzate of human erythrocytes to remove soluble cellular impurities using a frontal chromatographic process on an anion exchanger under conditions of selective ab
Publikováno v:
Applied Biochemistry and Microbiology. 42:354-359
Polycondensation of a catalase (EC 1.11.1.6) with glutaraldehyde in order to stabilize the quaternary structure of an enzyme, maintain its activity, and protect it from thermal denaturation was studied. Synthesis showed a superequivalent utilization
Publikováno v:
Russian Journal of Applied Chemistry. 76:1798-1802
Condensation of glutaric aldehyde with amino acids to form oligomers of glutaric aldehyde was studied by differential microcalorimetry and analysis for the functional groups.
Publikováno v:
Russian Journal of Applied Chemistry. 75:974-979
Formation of glutaraldehyde oligomers (tri- and pentamers) in reaction of glutaraldehyde with bipolar ions (monoaminoacetic, α-aminoglutaric, and α,e-diaminocaproic acids and glutatione tripeptide) was studied.
Publikováno v:
ChemInform. 45
The review covers studies of the reactions of glutaraldehyde with dipolar ions of amino acids and proteins in neutral aqueous solutions. The formation of imines and the accompanying aldol condensation of glutaraldehyde are acid-catalyzed reactions.
Publikováno v:
ChemInform. 45
Development of the scientific principles involved in the creation of soluble macromolecular modifications of the native protein, hemoglobin, is surveyed. The main goal of the research is practical application of the results to develop blood substitut
Autor:
L. M. Stragovich, L. M. Bistrova, N. P. Kuznetsova, Selivanov Ea, L. R. Gudkin, R. N. Mishaeva
Publikováno v:
Artificial Cells, Blood Substitutes, and Biotechnology. 26:213-222
Polymer aspects of polycondensation of pyridoxylated hemoglobin with glutaraldehyde have been considered. On the basis of the investigation of reaction kinetics, the mechanism of chemical crosslinking of hemoglobin molecules into oligohemoglobin is p