Výsledky vyhledávání - "R N, La Motte"

B7-2 expression on tumor cells is important for the acquisition of cytotoxic T lymphocyte activity by spleen cells from low-dose-melphalan-treated MOPC-315 tumor bearers via a mechanism that requires either B7-1 or B7-2 expression on host antigen-presenting cells

Autor: Dorothy K. Sojka, Margalit B. Mokyr, R N La Motte

Publikováno v: Cancer Immunology, Immunotherapy. 49:10-22

We have previously shown that B7-2 (CD86) and, to a lesser extent, B7-1 (CD80) contribute to the curative effectiveness of low-dose melphalan (L-phenylalanine mustard) for mice bearing a large MOPC-315 tumor under conditions that lead to the acquisit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f71b08243969426c8f7b9eedd7a828
https://doi.org/10.1007/s002620050022

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Therapeutic effectiveness of the immunity elicited by P815 tumor cells engineered to express the B7-2 costimulatory molecule

Autor: R N La Motte, Margalit B. Mokyr, Jeffrey A. Bluestone, Michael Rubin, Jeffrey M. Leiden, E Barr

Publikováno v: Cancer Immunology, Immunotherapy. 42:161-169

It is well accepted that inoculation of B7-1-transfected tumor cells into normal mice leads to tumor rejection and subsequent resistance to challenge. However, the effectiveness of B7-2-transfected tumor cells in eliciting protective antitumor immuni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::987a69518872a7156c00936977361cb4
https://doi.org/10.1007/s002620050266

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Host B7-1 and B7-2 costimulatory molecules contribute to the eradication of B7-1-transfected P815 tumor cells via a CD8+ T cell-dependent mechanism

Autor: R N, La Motte, A H, Sharpe, J A, Bluestone, M B, Mokyr

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 162(8)

B7-1 (CD80)-transfected P815 tumor cells were previously shown to elicit tumor-eradicating immunity that leads to the regression of B7-1+ P815 tumors after transient growth in normal syngeneic (DBA/2) mice. Here, we show that not only the B7-1 molecu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b85e8618dc788fd2be3cbfff9d479e21
https://pubmed.ncbi.nlm.nih.gov/10202025

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Importance of B7-1-expressing host antigen-presenting cells for the eradication of B7-2 transfected P815 tumor cells

Autor: R N, La Motte, A H, Sharpe, J A, Bluestone, M B, Mokyr

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 161(12)

We have previously shown that B7-2 (CD86)-transfected P815 tumor cells elicit tumor-eradicating immunity that leads to the regression of the B7-2+ P815 tumor after transient growth in normal DBA/2 mice. Here, we show that both the B7-2 and B7-1 (CD80

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1e57993fbb6f15f037116c61149966a5
https://pubmed.ncbi.nlm.nih.gov/9862681

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