Zobrazeno 1 - 10
of 31
pro vyhledávání: '"R N, DuBois"'
Autor:
O. Margalit, R. N. DuBois, Murali Ravoori, Sanjaya Singh, Vikas Kundra, David G. Menter, Sun-Hee Kim, Wei Wei
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Quantifying tumor burden is important for following the natural history of orthotopic colon cancer and therapeutic efficacy. Bioluminescence imaging (BLI) is commonly used for such assessment and has both advantages and limitations. We compared BLI a
Autor:
R. N. Dubois
Publikováno v:
Alimentary Pharmacology & Therapeutics. 14:64-67
Summary Use of nonsteroidal anti-inflammatory drugs such as aspirin, which are known to inhibit cyclooxygenase activity, reduces the relative risk of colorectal cancer in humans by 40–50%. Animal and human studies have shown a 50–80% reduction in
Autor:
H M, Kandil, R N, Dubois
Publikováno v:
Methods in molecular medicine. 50
Most epidemiological studies (1-7) support a protective role of aspirin and nonsteroidal antiinflammatory drugs (NSAIDs) against colorectal cancer. People who (by their report) take aspirin regularly have about a 50% decrease in the incidence (3,4) a
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(10)
It has been proposed that Cyclooxygenase (COX)-2 inhibitors may be able to enhance the effects of chemotherapeutic or radiation treatment; however, currently few studies have been reported that define the radiation-enhancing effect of COX-2 inhibitor
Autor:
J M, Kurie, R N, Dubois
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(9)
Publikováno v:
Digestive diseases and sciences. 46(4)
Barrett's epithelium is a recognized premalignant condition for esophageal adenocarcinoma. Nonsteroidal antiinflammatory drugs (NSAIDs) decrease the relative risk of colon cancer in humans and the esophageal tumor load in carcinogen-treated mice. Pre
Publikováno v:
Cancer research. 61(6)
Cyclooxygenase (COX) 2 expression is regulated via the Ras signaling pathway, and induction of mutated Ras rapidly increases COX-2 levels in intestinal epithelial cells. Protein kinase B (Akt/PKB) is an important effector of Ras signaling and a criti
Publikováno v:
Cancer research. 60(21)
Nonsteroidal anti-inflammatory drugs have potential for use in the prevention and/or treatment of colorectal cancer. We have studied the cytotoxic effect of a specific COX-2 inhibitor, celecoxib, against LLC, HCA-7, and HCT-15 cells grown in cell cul
Autor:
P E, Lipsky, S B, Abramson, F C, Breedveld, P, Brook, R, Burmester, F, Buttgereit, G W, Cannon, F, Catella-Lawson, L J, Crofford, M, Doherty, M, Dougados, R N, DuBois, J, Froelich, L A, Garcia Rodriguez, A, Gibofsky, S, Hernandez-Diaz, M C, Hochberg, A, Krause, M H, Liang, K, Machold, P M, Peloso, L G, Raisz, B, Schayes, J M, Scheiman, L S, Simon, J, Smolen
Publikováno v:
The Journal of rheumatology. 27(6)
Autor:
R N, Dubois
Publikováno v:
Alimentary pharmacologytherapeutics. 14
Use of nonsteroidal anti-inflammatory drugs such as aspirin, which are known to inhibit cyclooxygenase activity, reduces the relative risk of colorectal cancer in humans by 40-50%. Animal and human studies have shown a 50-80% reduction in tumour mult