Zobrazeno 1 - 10
of 130
pro vyhledávání: '"R N, Dehaven"'
Autor:
D L, DeHaven-Hudkins, L C, Burgos, J A, Cassel, J D, Daubert, R N, DeHaven, E, Mansson, H, Nagasaka, G, Yu, T, Yaksh
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 289(1)
The antihyperalgesic properties of the opiate antidiarrheal agent loperamide (ADL 2-1294) were investigated in a variety of inflammatory pain models in rodents. Loperamide exhibited potent affinity and selectivity for the cloned micro (Ki = 3 nM) com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::51369809fda9afbede3587cdc02f18ec
https://pubmed.ncbi.nlm.nih.gov/10087042
https://pubmed.ncbi.nlm.nih.gov/10087042
Identification of allosteric antagonists of receptor-guanine nucleotide-binding protein interactions
Publikováno v:
Molecular pharmacology. 37(2)
A series of compounds that inhibit the coupling of the alpha 2-adrenergic receptor and the beta 2-adrenergic receptor to the guanine nucleotide-binding proteins (G proteins) Gi and Gs, respectively, have been identified. This inhibition of G protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1152d1fef65dcaa3db1a133143f0f1e5
https://pubmed.ncbi.nlm.nih.gov/2154676
https://pubmed.ncbi.nlm.nih.gov/2154676
Autor:
T. R. Jones, Y. Guindon, R. Young, E. Champion, L. Charette, D. Denis, D. Ethier, R. Hamel, A. W. Ford-Hutchinson, R. Fortin, G. Letts, P. Masson, C. McFarlane, H. Piechuta, J. Rokach, C. Yoakim, R. N. DeHaven, A. Maycock, S. S. Pong
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 64:1535-1542
L-648,051, sodium 4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propylsulfonyl]-γ-oxo-benzenebutanoate is a selective and competitive inhibitor of [3H]leukotriene D4 (KB value of 4.0 μM) and to a lesser extent [3H]leukotriene C4 (Ki value of 36.7 μM) b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba167439a9118e83128f33320226650
https://doi.org/10.1139/y86-258
https://doi.org/10.1139/y86-258
Publikováno v:
Journal of Biological Chemistry. 258:9616-9619
A high affinity binding site for leukotriene C4 (LTC4), one component of slow reacting substance of anaphylaxis, has been identified in a membrane preparation from rat lung. As measured by a filtration technique, [3H]LTC4 binding was saturable, speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a74ecabb74c9a5a726f7d43acb10fb87
https://doi.org/10.1016/s0021-9258(17)44539-x
https://doi.org/10.1016/s0021-9258(17)44539-x
Publikováno v:
Chemical Communications; 8/14/2024, Vol. 60 Issue 63, p8224-8227, 4p
Autor:
T R, Jones, Y, Guindon, E, Champion, L, Charette, R N, DeHaven, D, Denis, D, Ethier, A W, Ford-Hutchinson, R, Fortin, R, Frenette
Publikováno v:
Advances in prostaglandin, thromboxane, and leukotriene research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aec7218d6533f9a3eb64c2cf9197be66
https://pubmed.ncbi.nlm.nih.gov/2823551
https://pubmed.ncbi.nlm.nih.gov/2823551
Autor:
R N, Young, Y, Guindon, T R, Jones, A W, Ford-Hutchinson, P, Bélanger, E, Champion, L, Charette, R N, DeHaven, D, Denis, R, Fortin
Publikováno v:
Advances in prostaglandin, thromboxane, and leukotriene research. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8dd993bc1b0e26a5f5030425f443337e
https://pubmed.ncbi.nlm.nih.gov/3028100
https://pubmed.ncbi.nlm.nih.gov/3028100
Autor:
T. R. Jones, R. Young, E. Champion, L. Charette, D. Denis, A. W. Ford-Hutchinson, R. Frenette, J-Y. Gauthier, Y. Guindon, M. Kakushima, P. Masson, C. McFarlane, H. Piechuta, J. Rokach, R. Zamboni, R. N. DeHaven, A. Maycock, S. S. Pong
Publikováno v:
Canadian journal of physiology and pharmacology. 64(8)
L-649,923, Sodium (βs*, γR*)-4-(3-(4-acetyi-3-hydroxy-2-propylphenoxy)propylthio)-γ-hydroxy-β-methylbenzenebutanoate is a selective and competitive inhibitor of [3H]leukotriene D4 (Ki value of 400 nM) and to a lesser extent [3H]leukotriene C4 (Ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae85759b0ae24402eaea966f7f9d2685
https://pubmed.ncbi.nlm.nih.gov/3024787
https://pubmed.ncbi.nlm.nih.gov/3024787
Publikováno v:
The Journal of biological chemistry. 258(16)
A high affinity binding site for leukotriene C4 (LTC4), one component of slow reacting substance of anaphylaxis, has been identified in a membrane preparation from rat lung. As measured by a filtration technique, [3H]LTC4 binding was saturable, speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b1f3ea802694cf628e4a2b86904ed92
https://pubmed.ncbi.nlm.nih.gov/6885762
https://pubmed.ncbi.nlm.nih.gov/6885762
Autor:
R N, Young, T R, Jones, J G, Atkinson, P, Bélanger, E, Champion, D, Denis, R N, DeHaven, A W, Ford-Hutchinson, R, Fortin, R, Frenette
Publikováno v:
Advances in prostaglandin, thromboxane, and leukotriene research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba9233541ee7dbfacc47e43c0d590793
https://pubmed.ncbi.nlm.nih.gov/2959111
https://pubmed.ncbi.nlm.nih.gov/2959111