Zobrazeno 1 - 10
of 118
pro vyhledávání: '"R N, Curnow"'
A suite of tests to evaluate the statistical significance of protein sequence similarities is developed for use in data bank searches. The tests are based on the Wilbur-Lipman word-search algorithm, and take into account the sequence lengths and comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::384852a46b16041c50dcf7af096c42ed
https://ora.ox.ac.uk/objects/uuid:d86122bb-b155-4bc2-8c59-e78a532ce955
https://ora.ox.ac.uk/objects/uuid:d86122bb-b155-4bc2-8c59-e78a532ce955
An accurate approximation is derived to the distribution of the length of the longest matching word present between two random DNA sequences of finite length, using only elementary probability arguments. The distribution is shown to be consistent wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8817c7c6f7cfa1722f696b8c0b6eddcc
https://ora.ox.ac.uk/objects/uuid:6f0943bf-8a3e-4a7e-9ab4-adc0b7881cff
https://ora.ox.ac.uk/objects/uuid:6f0943bf-8a3e-4a7e-9ab4-adc0b7881cff
A method is developed, based on word-searching, which provides a rapid test for the statistical significance of DNA sequence similarities for use in databank searching. The method makes allowance for the lengths and dinucleotide compositions of the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb8a6c0c8af749f852d0ef269907e4ff
https://ora.ox.ac.uk/objects/uuid:78a25f65-545d-425b-841d-620f3d1c6bb0
https://ora.ox.ac.uk/objects/uuid:78a25f65-545d-425b-841d-620f3d1c6bb0
Publikováno v:
Bulletin of Volcanology. 63:98-111
A method is described that enables a variety of maps, which indicate the probabilities of deposition, to be constructed in a reproducible manner from the stratigraphie information typically available at well-studied stratovoicanoes. These maps can th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d07c500f87125210747d2781e583e8a
https://doi.org/10.1007/s004450100128
https://doi.org/10.1007/s004450100128
Publikováno v:
Genetic Epidemiology. 15:193-200
Several extensions of the transmission/disequilibrium test (TDT) to multi-allelic markers now exist. In some of these, however, separate tests must be performed on male and female parents because of the non-independence of parental transmission patte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a727e59c0bd361d1b4f4ac66aa2de77a
https://doi.org/10.1002/(sici)1098-2272(1998)15:2<193::aid-gepi7>3.0.co
https://doi.org/10.1002/(sici)1098-2272(1998)15:2<193::aid-gepi7>3.0.co
Publikováno v:
Annals of Human Genetics. 61:335-350
A likelihood ratio test of disease-marker association is proposed, based on the observation of marker alleles transmitted from parents to affected children. The proposed association test has the advantage of identifying the population pattern of dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::926d0863cb697d5a77f62a9959218b0b
https://doi.org/10.1017/s0003480097006349
https://doi.org/10.1017/s0003480097006349
Publikováno v:
John Whittaker
ResearcherID
Scopus-Elsevier
ResearcherID
Scopus-Elsevier
A powerful test for population association of a disease with alleles at a bi-allelic marker locus is the transmission/disequilibrium test (TDT). A generalization of the test to multi-allelic marker loci is proposed which utilizes the maximal associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4a769a9c5f16e2d0c9ab2ff98056953
https://doi.org/10.1017/s0003480096005921
https://doi.org/10.1017/s0003480096005921
Autor:
R. N. Curnow
Publikováno v:
American Journal of Medical Genetics. 52:108-114
The number of recessive diseases, such as cystic fibrosis, in which some but not all of the mutations causing the disease can be detected using genetic probes, is certain to increase. For counselling purposes, the probability that a consultand known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ad6dc9e8fea8b27f544210ad05ea74
https://doi.org/10.1002/ajmg.1320520121
https://doi.org/10.1002/ajmg.1320520121
Publikováno v:
Journal of Nutritional Medicine. 4:25-31
The purpose of this paper is to stress the importance of studying the joint effects of several causative factors on a dependent variable. The data analyzed are concerned with the effects of several trace elements measured in the hair and saliva of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36d8938f0ad586be8ab085670956ab98
https://doi.org/10.3109/13590849409034537
https://doi.org/10.3109/13590849409034537
Autor:
Fionn Murtagh, R. N. Curnow, J. Felsenstein, P. H. A. Sneath, Margaret H. Wright, A. W. Bowman, P. M. E. Altham, J. N. R. Jeffers, Martin Crowder, P. M. Bentler, Šarnas Raudys
Publikováno v:
Journal of Classification. 8:115-148
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::212a64844dfb47c7471d70c617c8eb75
https://doi.org/10.1007/bf02616251
https://doi.org/10.1007/bf02616251