Zobrazeno 1 - 10
of 507
pro vyhledávání: '"R Muratore"'
Autor:
Lien D. Nguyen, Zhiyun Wei, M. Catarina Silva, Sergio Barberán-Soler, Jiarui Zhang, Rosalia Rabinovsky, Christina R. Muratore, Jonathan M. S. Stricker, Colin Hortman, Tracy L. Young-Pearse, Stephen J. Haggarty, Anna M. Krichevsky
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract MicroRNAs (miRNAs) regulate fundamental biological processes by silencing mRNA targets and are dysregulated in many diseases. Therefore, miRNA replacement or inhibition can be harnessed as potential therapeutics. However, existing strategies
Externí odkaz:
https://doaj.org/article/b8a8e54f65f640bfad7b904c07567fde
Autor:
Luis Fonseca-Ornelas, Jonathan M. S. Stricker, Stephanie Soriano-Cruz, Beatrice Weykopf, Ulf Dettmer, Christina R. Muratore, Clemens R. Scherzer, Dennis J. Selkoe
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract α-Synuclein (αSyn) aggregation in Lewy bodies and neurites defines both familial and ‘sporadic’ Parkinson’s disease. We previously identified α-helically folded αSyn tetramers, in addition to the long-known unfolded monomers, in no
Externí odkaz:
https://doaj.org/article/e13ccbb7dccf40c0b670bee0a405f972
Autor:
Saranna Fanning, Haley Cirka, Jennifer L. Thies, Jooyoung Jeong, Sarah M. Niemi, Joon Yoon, Gary P. H. Ho, Julian A. Pacheco, Ulf Dettmer, Lei Liu, Clary B. Clish, Kevin J. Hodgetts, John N. Hutchinson, Christina R. Muratore, Guy A. Caldwell, Kim A. Caldwell, Dennis Selkoe
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-17 (2022)
Abstract Synucleinopathy (Parkinson’s disease (PD); Lewy body dementia) disease-modifying treatments represent a huge unmet medical need. Although the PD-causing protein α-synuclein (αS) interacts with lipids and fatty acids (FA) physiologically
Externí odkaz:
https://doaj.org/article/a05e96cff1274ee38def6a5cf8769047
Autor:
S. Bertuccio, G. Tardiolo, F. M. Giambò, G. Giuffrè, R. Muratore, C. Settimo, A. Raffa, S. Rigano, A. Bramanti, N. Muscarà, M. C. De Cola
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background The cloud is a promising resource for data sharing and computing. It can optimize several legacy processes involving different units of a company or more companies. Recently, cloud technology applications are spreading out in the
Externí odkaz:
https://doaj.org/article/5b65da94fe764d3bba43f5075affbf68
Autor:
Christina R. Muratore, Constance Zhou, Meichen Liao, Marty A. Fernandez, Walter M. Taylor, Valentina N. Lagomarsino, Richard V. Pearse, II, Heather C. Rice, Joseph M. Negri, Amy He, Priya Srikanth, Dana G. Callahan, Taehwan Shin, Monica Zhou, David A. Bennett, Scott Noggle, J. Christopher Love, Dennis J. Selkoe, Tracy L. Young-Pearse
Publikováno v:
Stem Cell Reports, Vol 9, Iss 6, Pp 1868-1884 (2017)
Summary: Alzheimer's disease (AD) induces memory and cognitive impairment in the absence of motor and sensory deficits during its early and middle course. A major unresolved question is the basis for this selective neuronal vulnerability. Aβ, whic
Externí odkaz:
https://doaj.org/article/9f03abb62b1343ab8aa8f519af659d78
Autor:
Priya Srikanth, Karam Han, Dana G. Callahan, Eugenia Makovkina, Christina R. Muratore, Matthew A. Lalli, Honglin Zhou, Justin D. Boyd, Kenneth S. Kosik, Dennis J. Selkoe, Tracy L. Young-Pearse
Publikováno v:
Cell Reports, Vol 12, Iss 9, Pp 1414-1429 (2015)
Genetic and clinical association studies have identified disrupted in schizophrenia 1 (DISC1) as a candidate risk gene for major mental illness. DISC1 is interrupted by a balanced chr(1;11) translocation in a Scottish family in which the translocatio
Externí odkaz:
https://doaj.org/article/cdc49440096440b5931eddc398674d5f
Autor:
Lien D. Nguyen, Zhiyun Wei, M. Catarina Silva, Sergio Barberán-Soler, Rosalia Rabinovsky, Christina R. Muratore, Jonathan M. S. Stricker, Colin Hortman, Tracy L. Young-Pearse, Stephen J. Haggarty, Anna M. Krichevsky
SUMMARYMicroRNAs (miRNAs) are short RNAs that regulate fundamental biological processes. miR-132, a key miRNA with established functions in Tau homeostasis and neuroprotection, is consistently downregulated in Alzheimer’s disease (AD) and other tau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dc8ab5e5cd01989c43cc4a62ce97ab0
https://doi.org/10.1101/2022.11.01.514550
https://doi.org/10.1101/2022.11.01.514550
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105807 (2014)
Several protocols have been developed for human induced pluripotent stem cell neuronal differentiation. We compare several methods for forebrain cortical neuronal differentiation by assessing cell morphology, immunostaining and gene expression. We ev
Externí odkaz:
https://doaj.org/article/abc1af4d43fa49bf934eabb32e46a59a
Autor:
C. Settimo, S. Bertuccio, G. Giuffrè, R. Muratore, A. Raffa, M. C. De Cola, F. M. Giambò, N. Muscarà, Giuseppe Tardiolo, Alessia Bramanti, S. Rigano
Publikováno v:
BMC Medical Informatics and Decision Making
BMC Medical Informatics and Decision Making, Vol 21, Iss 1, Pp 1-9 (2021)
BMC Medical Informatics and Decision Making, Vol 21, Iss 1, Pp 1-9 (2021)
BackgroundThe cloud is a promising resource for data sharing and computing. It can optimize several legacy processes involving different units of a company or more companies. Recently, cloud technology applications are spreading out in the healthcare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f18c3dc2c396f2777ab161b48b16308
http://europepmc.org/articles/PMC7789295
http://europepmc.org/articles/PMC7789295