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Akademický článek

Hippocampal astrocytes induce sex-dimorphic effects on memory

Autor: Samantha M. Meadows, Fernando Palaguachi, Minwoo Wendy Jang, Avital Licht-Murava, Daniel Barnett, Till S. Zimmer, Constance Zhou, Samantha R. McDonough, Adam L. Orr, Anna G. Orr

Publikováno v: Cell Reports, Vol 43, Iss 6, Pp 114278- (2024)

Summary: Astrocytic receptors influence cognitive function and can promote behavioral deficits in disease. These effects may vary based on variables such as biological sex, but it is not known if the effects of astrocytic receptors are dependent on s

Externí odkaz: https://doaj.org/article/b615039c5bc64967aff8c3199aa8fe35

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Akademický článek

E-cigarette-induced pulmonary inflammation and dysregulated repair are mediated by nAChR α7 receptor: role of nAChR α7 in SARS-CoV-2 Covid-19 ACE2 receptor regulation

Autor: Qixin Wang, Isaac K. Sundar, Dongmei Li, Joseph H. Lucas, Thivanka Muthumalage, Samantha R. McDonough, Irfan Rahman

Publikováno v: Respiratory Research, Vol 21, Iss 1, Pp 1-17 (2020)

Abstract Electronic cigarette (e-cig) vaping is increasing rapidly in the United States, as e-cigs are considered less harmful than combustible cigarettes. However, limited research has been conducted to understand the possible mechanisms that mediat

Externí odkaz: https://doaj.org/article/3ceb37c18cba42e88c358463e17ae8d3

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Akademický článek

Dysregulated repair and inflammatory responses by e‐cigarette‐derived inhaled nicotine and humectant propylene glycol in a sex‐dependent manner in mouse lung

Autor: Qixin Wang, Naushad Ahmad Khan, Thivanka Muthumalage, Gina R. Lawyer, Samantha R. McDonough, Tsai‐Der Chuang, Ming Gong, Isaac K. Sundar, Virender K. Rehan, Irfan Rahman

Publikováno v: FASEB BioAdvances, Vol 1, Iss 10, Pp 609-623 (2019)

Abstract Nicotine inhalation via electronic cigarettes (e‐cigs) is an emerging concern. However, little is known about the acute toxicity in the lungs following inhalation of nicotine‐containing e‐cig aerosols. We hypothesized that acute exposu

Externí odkaz: https://doaj.org/article/d45a458a9c65407fafc9212ed104c9be

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Akademický článek

Systemic biomarkers in electronic cigarette users: implications for noninvasive assessment of vaping-associated pulmonary injuries

Autor: Kameshwar P. Singh, Gina Lawyer, Thivanka Muthumalage, Krishna P. Maremanda, Naushad Ahmad Khan, Samantha R. McDonough, Dongxia Ye, Scott McIntosh, Irfan Rahman

Publikováno v: ERJ Open Research, Vol 5, Iss 4 (2019)

Background Electronic cigarettes (e-cigs) were introduced as electronic nicotine delivery systems, and have become very popular in the USA and globally. There is a paucity of data on systemic injury biomarkers of vaping in e-cig users that can be use

Externí odkaz: https://doaj.org/article/7f634d471d004fbdab276c646ec6075d

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Akademický článek

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