Zobrazeno 1 - 10
of 4 577
pro vyhledávání: '"R Matthews"'
Autor:
Christopher R. Matthews
Publikováno v:
Humanities & Social Sciences Communications, Vol 11, Iss 1, Pp 1-5 (2024)
Social science is not as it should be – I think we have lost contact with what matters. Many scholars have made similar laments and directed their attention at disciplines in an attempt to mark out a more virtuous and effective future. Such attempt
Externí odkaz:
https://doaj.org/article/635244cd0e4e4093a966359b41767b50
Autor:
Jiang Li, Stephanie L. Rouse, Ian R. Matthews, Yesai Park, Yasmin Eltawil, Elliott H. Sherr, Dylan K. Chan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Cisplatin is a commonly used chemotherapy agent with a nearly universal side effect of sensorineural hearing loss. The cellular mechanisms underlying cisplatin ototoxicity are poorly understood. Efforts in drug development to prevent or reve
Externí odkaz:
https://doaj.org/article/98976efb3a60470ab2c0b28fd24b4739
Autor:
Mathieu Cayla, Christos Spanos, Kirsty McWilliam, Eliza Waskett, Juri Rappsilber, Keith R. Matthews
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Adaptation to a change of environment is an essential process for survival, in particular for parasitic organisms exposed to a wide range of hosts. Such adaptations include rapid control of gene expression through the formation of membranele
Externí odkaz:
https://doaj.org/article/866671752bbf4a37af8f1973150e02ad
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Moderate noise exposure induces cochlear synaptopathy, the loss of afferent ribbon synapses between cochlear hair cells and spiral ganglion neurons, which is associated with functional hearing decline. Prior studies have demonstrated noise-i
Externí odkaz:
https://doaj.org/article/29119580ad1349afb31ce1e9f104784b
Autor:
Isabel Saldanha, Martha Betson, Christina Vrettou, Edith Paxton, James Nixon, Peter Tennant, Adrian Ritchie, Keith R. Matthews, Liam J. Morrison, Stephen J. Torr, Lucas J. Cunningham
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Animal African trypanosomiasis (AAT) is a significant food security and economic burden in sub-Saharan Africa. Current AAT empirical and immunodiagnostic surveillance tools suffer from poor sensitivity and specificity, with blood sampling re
Externí odkaz:
https://doaj.org/article/07898443b1c145f8bea0260d12f3222b
Autor:
Hung-Chin Wu, Shayla Nikzad, Chenxin Zhu, Hongping Yan, Yang Li, Weijun Niu, James R. Matthews, Jie Xu, Naoji Matsuhisa, Prajwal Kammardi Arunachala, Reza Rastak, Christian Linder, Yu-Qing Zheng, Michael F. Toney, Mingqian He, Zhenan Bao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Stretchable polymer semiconductors (PSCs) have seen great advancements alongside the development of soft electronics. But it remains a challenge to simultaneously achieve high charge carrier mobility and stretchability. Herein, we report the
Externí odkaz:
https://doaj.org/article/d12ebbc959464b08aa298d13b32ef74e
Autor:
Mariam Okhovat, Jake VanCampen, Kimberly A. Nevonen, Lana Harshman, Weiyu Li, Cora E. Layman, Samantha Ward, Jarod Herrera, Jackson Wells, Rory R. Sheng, Yafei Mao, Blaise Ndjamen, Ana C. Lima, Katinka A. Vigh-Conrad, Alexandra M. Stendahl, Ran Yang, Lev Fedorov, Ian R. Matthews, Sarah A. Easow, Dylan K. Chan, Taha A. Jan, Evan E. Eichler, Sandra Rugonyi, Donald F. Conrad, Nadav Ahituv, Lucia Carbone
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Topological associating domains (TADs) are self-interacting genomic units crucial for shaping gene regulation patterns. Despite their importance, the extent of their evolutionary conservation and its functional implications remain largely un
Externí odkaz:
https://doaj.org/article/65e9bbc94a464705ac4ea7c071b55e77
Autor:
Federico Bertagna, Shiraz Ahmad, Rebecca Lewis, S. Ravi P. Silva, Johnjoe McFadden, Christopher L.-H. Huang, Hugh R. Matthews, Kamalan Jeevaratnam
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
IntroductionThe loose-patch clamp technique was first developed and used in native amphibian skeletal muscle (SkM), offering useful features complementing conventional sharp micro-electrode, gap, or conventional patch voltage clamping. It demonstrate
Externí odkaz:
https://doaj.org/article/94e8beade09943b6a18bc501602977b3
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1456 (2024)
The hyperactivation of the sympathetic nervous system (SNS) is linked to obesity, hypertension, and type 2 diabetes, which are characterized by elevated norepinephrine (NE) levels. Previous research has shown increased sodium-dependent glucose cotran
Externí odkaz:
https://doaj.org/article/bf22b891c9474a73ac8bd0637020363d
Autor:
Eleanor Silvester, Balazs Szoor, Alasdair Ivens, Georgina Awuah-Mensah, Catarina Gadelha, Bill Wickstead, Keith R Matthews
Publikováno v:
PLoS Pathogens, Vol 20, Iss 2, p e1011889 (2024)
Trypanosomatid parasites undergo developmental regulation to adapt to the different environments encountered during their life cycle. In Trypanosoma brucei, a genome wide selectional screen previously identified a regulator of the protein family ESAG
Externí odkaz:
https://doaj.org/article/d12859edc02f4c27a5132d16e0815e5b