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pro vyhledávání: '"R Marcel Kling"'
Autor:
Laura Andrau, Margarita Kurek, R Marcel Kling, Andrew Craig Donohue, Harrison Sikanyika, David M. Shackleford, Andrew F. Wilks, John Thomas Feutrill, Tracy L. Nero, Emmanuelle Fantino, Herbert R. Treutlein, Michelle Farrugia, Ian D Phillips, Michelle Leanne Styles, David Gerard Bourke, Jun Zeng, Thao Kim Nu Nguyen, Christopher J. Burns, James T. Palmer, Max Joffe, Xianyong Bu, Stephen Su, Susan A. Charman
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:5887-5892
A series of phenylaminopyrimidines has been identified as inhibitors of Janus kinases (JAKs). Development of this initial series led to the potent JAK2/JAK1 inhibitor CYT387 (N-(cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]-benzam