Impact of Daily Lower‐Body Negative Pressure or Cycling Followed by Venous Constrictive Thigh Cuffs on Bedrest‐Induced Orthostatic Intolerance

Autor: Jan‐Niklas Hönemann, Fabian Hoffmann, Laura de Boni, Peter Gauger, Edwin Mulder, Stefan Möstl, Karsten Heusser, Marie‐Therese Schmitz, Marcel Halbach, Steven S. Laurie, Stuart M. C. Lee, Brandon R. Macias, Jens Jordan, Jens Tank

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 21 (2024)

Background Orthostatic intolerance occurs following immobilization in patients on Earth and in astronauts after spaceflight. Head‐down tilt bedrest is a terrestrial model for weightlessness and induces orthostatic intolerance. We hypothesized that

Externí odkaz: https://doaj.org/article/eb91adcfe3784f7ba9482e5d52f7ba22

Ricardo Macías Picavea. Valladolid. Ediciones del Ayuntamiento de Valladolid. Colección de Autores vallisoletanos. Serie clásicos R. Macías Picavea I. González Gallego R. Martín de la Guardia G. Pérez Sánchez M. Sánchez Agustí L. Serrano Blanco

Autor: Guerrero, R. Clara Revuelta

Publikováno v: Revista Española de Pedagogía, 2001 Jan 01. 59(218), 177-181.

Externí odkaz: https://www.jstor.org/stable/23765876

Lacking Immunotherapy Biomarkers for Biliary Tract Cancer: A Comprehensive Systematic Literature Review and Meta-Analysis

Autor: Giorgio Frega, Fernando P. Cossio, Jesus M. Banales, Vincenzo Cardinale, Rocio I. R. Macias, Chiara Braconi, Angela Lamarca

Publikováno v: Cells, Vol 12, Iss 16, p 2098 (2023)

Background: Immunotherapy has recently been incorporated into the spectrum of biliary tract cancer (BTC) treatment. The identification of predictive response biomarkers is essential in order to identify those patients who may benefit most from this n

Externí odkaz: https://doaj.org/article/a27456594e9c46b1b086f68ea1e60394

I-SPY COVID adaptive platform trial for COVID-19 acute respiratory failure: rationale, design and operations

Autor: Carolyn S Calfee, Michael A Matthay, Paul Henderson, Martin Eklund, Laura J Esserman, Chirag Patel, Angela Haczku, Michelle Jung, Tony Oliver, Alessio Crippa, Andrea Discacciati, Kathleen D Liu, Ellen L Burnham, Nuala J Meyer, Fady A Youssef, Derek W Russell, Julie Lang, Kevin W Gibbs, Daniel C Files, Sheetal Gandotra, Purnema Madahar, Nathan K Cobb, Timothy E Albertson, Rajiv Sonti, John P Reilly, Alejandra Jauregui, Iván García, Luis E Huerta, Daniel Clark Files, Neil R Aggarwal, Adam L Asare, Jeremy R Beitler, Paul A Berger, George Cimino, Melissa H Coleman, Paul T Henderson, Caroline A G Ittner, Kashif T Khan, Jonathan L Koff, Mary LaRose, Joe Levitt, Ruixiao Lu, Jeffrey D McKeehan, Karl W Thomas, Aaron M Mittel, Albert F Yen, Alexis E Suarez, Alexis L Serra, Alpesh N Amin, Amanda Rosen, Amy L Dzierba, Anna D Barker, Ariel R Weisman, Brian M Daniel, Brian M Morrissey, Caroline AG Ittner, Chayse Jones, Christina Creel-Bulos, Christina M Angelucci, Diana Ng, Fredy Chaparro-Rojas, Gavin H Harris, Harsh V Barot, Heny Su, Jacqueline B Sutter, Jamal Dodin, Jerry S Lee, John Kazianis, Joshua F Detelich, Julie E Lang, Justin Muir, Katarzyna Gosek, Katherine L Nugent, Kimberly Yee, Laura G Rodrigues, Laura R Macias, Lindsey A Orr, Lindsie L Boerger, Lissette Rosario-Remigio, Lucia Kufa, Maged Tanios, Maria B Reyes, Max W Adelman, Maya M Juarez, Michelle Meyers, Mitchell P Sternlieb, Neil Aggarwal, Nilam S Mangalmurti, Patrice Jones, Paul L Saban, Peter S Marshall, Philiip A Robinson, Philip Yang, Rahul Nair, Richard Anthony Lee, Richard G Wunderink, Romina Wahab, Roxana A Lupu, Santhi I Kumar, Sara C Auld, Scott Fields, Se Fum Wong, Skyler J Pearson, Spencer Whealon, Timothy F Obermiller, Anita Darmanian, John Schicchi, Esmeralda Martinez, Farjad Sarafian, Julie Nguyen, Bethany Weiler-Lisowski, Jaime Wyatt, Daniel Blevins, Marylee Melendrez, Brenda Lopez, Hiwet Tzehaie, Omowunmi Amosu, Austin Simonson, Erin Hardy, Brett Lindgren, Gregory Peterfreund, Leigha Landreth, Lisa Parks

Publikováno v: BMJ Open, Vol 12, Iss 6 (2022)

Externí odkaz: https://doaj.org/article/480eafc2c901401aa40873075dcf1eb8

Spaceflight-Associated Vascular Remodeling and Gene Expression in Mouse Calvaria

Autor: Jamila H. Siamwala, Brandon R. Macias, Robert Healey, Brett Bennett, Alan R. Hargens

Publikováno v: Frontiers in Physiology, Vol 13 (2022)

Astronauts suffer from a loss of bone mass at a rate of 1.5% per month from lower regions of the body during the course of long-duration (>30 days) spaceflight, a phenomenon that poses important risks for returning crew. Conversely, a gain in bone ma

Externí odkaz: https://doaj.org/article/3362a6bac6e04576a54601bb823de737